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Differential impact of host-related factors on survival outcomes between IO+IO and IO+TKI in metastatic renal cell carcinoma: a multicenter retrospective study.

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Title: Differential impact of host-related factors on survival outcomes between IO+IO and IO+TKI in metastatic renal cell carcinoma: a multicenter retrospective study.
Authors: Sugimoto K; Department of Urology, Kindai University Faculty of Medicine, 3-1-14 Mihara-dai, Minami-ku, Sakai City, 589-8511, Osaka, Japan., Toyoda S; Department of Urology, Kindai University Faculty of Medicine, 3-1-14 Mihara-dai, Minami-ku, Sakai City, 589-8511, Osaka, Japan., Inoki L; Department of Urology, Kindai University Faculty of Medicine, 3-1-14 Mihara-dai, Minami-ku, Sakai City, 589-8511, Osaka, Japan., Mori K; Department of Urology, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan., Yanagisawa T; Department of Urology, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan., Tamura K; Department of Urology, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan., Nukaya T; Department of Urology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan., Maenosono R; Department of Urology, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan., Morinaka H; Department of Urology, Kawasaki Medical School, Kurashiki, Okayama, Japan., Nishimura S; Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Okayama, Japan., Bekku K; Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Okayama, Japan., Komura K; Department of Urology, Kawasaki Medical School, Kurashiki, Okayama, Japan., Takahara K; Department of Urology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan., Inamoto T; Department of Urology, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan., Azuma H; Department of Urology, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan., Fujita K; Department of Urology, Kindai University Faculty of Medicine, 3-1-14 Mihara-dai, Minami-ku, Sakai City, 589-8511, Osaka, Japan. kfujita@med.kindai.ac.jp.
Corporate Authors: JK-FOOT study group
Source: International journal of clinical oncology [Int J Clin Oncol] 2026 Jun 11. Date of Electronic Publication: 2026 Jun 11.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Tokyo Country of Publication: Japan NLM ID: 9616295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1437-7772 (Electronic) Linking ISSN: 13419625 NLM ISO Abbreviation: Int J Clin Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Differential impact of host-related factors on survival outcomes between IO+IO and IO+TKI in metastatic renal cell carcinoma: a multicenter retrospective study.
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  Data: <searchLink fieldCode="AU" term="%22Sugimoto+K%22">Sugimoto K</searchLink>; Department of Urology, Kindai University Faculty of Medicine, 3-1-14 Mihara-dai, Minami-ku, Sakai City, 589-8511, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Toyoda+S%22">Toyoda S</searchLink>; Department of Urology, Kindai University Faculty of Medicine, 3-1-14 Mihara-dai, Minami-ku, Sakai City, 589-8511, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Inoki+L%22">Inoki L</searchLink>; Department of Urology, Kindai University Faculty of Medicine, 3-1-14 Mihara-dai, Minami-ku, Sakai City, 589-8511, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Mori+K%22">Mori K</searchLink>; Department of Urology, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Yanagisawa+T%22">Yanagisawa T</searchLink>; Department of Urology, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Tamura+K%22">Tamura K</searchLink>; Department of Urology, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Nukaya+T%22">Nukaya T</searchLink>; Department of Urology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.<br /><searchLink fieldCode="AU" term="%22Maenosono+R%22">Maenosono R</searchLink>; Department of Urology, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Morinaka+H%22">Morinaka H</searchLink>; Department of Urology, Kawasaki Medical School, Kurashiki, Okayama, Japan.<br /><searchLink fieldCode="AU" term="%22Nishimura+S%22">Nishimura S</searchLink>; Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Okayama, Japan.<br /><searchLink fieldCode="AU" term="%22Bekku+K%22">Bekku K</searchLink>; Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Okayama, Japan.<br /><searchLink fieldCode="AU" term="%22Komura+K%22">Komura K</searchLink>; Department of Urology, Kawasaki Medical School, Kurashiki, Okayama, Japan.<br /><searchLink fieldCode="AU" term="%22Takahara+K%22">Takahara K</searchLink>; Department of Urology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.<br /><searchLink fieldCode="AU" term="%22Inamoto+T%22">Inamoto T</searchLink>; Department of Urology, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Azuma+H%22">Azuma H</searchLink>; Department of Urology, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Fujita+K%22">Fujita K</searchLink>; Department of Urology, Kindai University Faculty of Medicine, 3-1-14 Mihara-dai, Minami-ku, Sakai City, 589-8511, Osaka, Japan. kfujita@med.kindai.ac.jp.
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        Text: English
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      – TitleFull: Differential impact of host-related factors on survival outcomes between IO+IO and IO+TKI in metastatic renal cell carcinoma: a multicenter retrospective study.
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