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Protocol for the external validation of machine learning models for risk prediction in early-onset preeclampsia: a multicenter prospective cohort study.

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Title: Protocol for the external validation of machine learning models for risk prediction in early-onset preeclampsia: a multicenter prospective cohort study.
Authors: Domínguez-Del Olmo P; Department of Computer Architecture and Automation, Faculty of Informatics, Complutense University of Madrid, Madrid, Spain.; Spanish Network in Maternal, Neonatal, Child and Developmental Health Research (RICORS-SAMID), RD24/0013/0015, Instituto de Salud Carlos III, Madrid, Spain., Melchor I; Department of Obstetrics and Gynecology, Hospital Universitario Cruces, Instituto de Investigación Sanitaria BioBizkaia, Barakaldo, Bizkaia, Spain., Cánovas E; Department of Obstetrics and Gynecology, Hospital Universitario Virgen de La Arrixaca, IMIB/Arrixaca, Murcia, Spain., García-Manau P; Department of Obstetrics and Gynecology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain., Cahuana MJ; BCNatal - Barcelona Center for Maternal-Fetal and Neonatal Medicine (Hospital Clínic y Hospital Sant Joan de Deu), Institut Clínic de Ginecología, Obstetrícia I Neonatología, Fetal i+D Fetal Medicine Research Center, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Universidad de Barcelona, Barcelona, Spain., Pérez-Marqués M; Department of Obstetrics and Gynecology, Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain., Satorres E; Department of Obstetrics and Gynecology, Hospital Universitari i Politècnic La Fe, Valencia, Spain., Bugatto F; Department of Child and Mother Health and Radiology, School of Medicine, University of Cádiz and Division of Maternal and Fetal Medicine, Department of Obstetrics and Gynecology Puerta del Mar University Hospital, Cádiz, Spain.; Biomedical Research and Innovation Institute of Cádiz (INiBICA), Cádiz, Spain., Villalaín C; Spanish Network in Maternal, Neonatal, Child and Developmental Health Research (RICORS-SAMID), RD24/0013/0015, Instituto de Salud Carlos III, Madrid, Spain.; Department of Obstetrics and Gynecology, Hospital Universitario 12 de Octubre, Madrid, Spain.; Instituto de Investigación Hospital 12 de Octubre (imas12), Madrid, Spain.; Facultad de Medicina, Universidad Complutense de Madrid (UCM), Madrid, Spain., Robisco E; Department of Obstetrics and Gynecology, Hospital Universitario 12 de Octubre, Madrid, Spain.; Instituto de Investigación Hospital 12 de Octubre (imas12), Madrid, Spain., L Ayala J; Department of Computer Architecture and Automation, Faculty of Informatics, Complutense University of Madrid, Madrid, Spain.; Spanish Network in Maternal, Neonatal, Child and Developmental Health Research (RICORS-SAMID), RD24/0013/0015, Instituto de Salud Carlos III, Madrid, Spain., Galindo A; Spanish Network in Maternal, Neonatal, Child and Developmental Health Research (RICORS-SAMID), RD24/0013/0015, Instituto de Salud Carlos III, Madrid, Spain.; Department of Obstetrics and Gynecology, Hospital Universitario 12 de Octubre, Madrid, Spain.; Instituto de Investigación Hospital 12 de Octubre (imas12), Madrid, Spain.; Facultad de Medicina, Universidad Complutense de Madrid (UCM), Madrid, Spain., Herraiz I; Spanish Network in Maternal, Neonatal, Child and Developmental Health Research (RICORS-SAMID), RD24/0013/0015, Instituto de Salud Carlos III, Madrid, Spain. ignacio.herraiz@salud.madrid.org.; Department of Obstetrics and Gynecology, Hospital Universitario 12 de Octubre, Madrid, Spain. ignacio.herraiz@salud.madrid.org.; Instituto de Investigación Hospital 12 de Octubre (imas12), Madrid, Spain. ignacio.herraiz@salud.madrid.org.; Facultad de Medicina, Universidad Complutense de Madrid (UCM), Madrid, Spain. ignacio.herraiz@salud.madrid.org.
Source: BMC pregnancy and childbirth [BMC Pregnancy Childbirth] 2026 Jun 11. Date of Electronic Publication: 2026 Jun 11.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100967799 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-2393 (Electronic) Linking ISSN: 14712393 NLM ISO Abbreviation: BMC Pregnancy Childbirth Subsets: MEDLINE
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  Data: Protocol for the external validation of machine learning models for risk prediction in early-onset preeclampsia: a multicenter prospective cohort study.
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  Data: <searchLink fieldCode="AU" term="%22Domínguez-Del+Olmo+P%22">Domínguez-Del Olmo P</searchLink>; Department of Computer Architecture and Automation, Faculty of Informatics, Complutense University of Madrid, Madrid, Spain.; Spanish Network in Maternal, Neonatal, Child and Developmental Health Research (RICORS-SAMID), RD24/0013/0015, Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Melchor+I%22">Melchor I</searchLink>; Department of Obstetrics and Gynecology, Hospital Universitario Cruces, Instituto de Investigación Sanitaria BioBizkaia, Barakaldo, Bizkaia, Spain.<br /><searchLink fieldCode="AU" term="%22Cánovas+E%22">Cánovas E</searchLink>; Department of Obstetrics and Gynecology, Hospital Universitario Virgen de La Arrixaca, IMIB/Arrixaca, Murcia, Spain.<br /><searchLink fieldCode="AU" term="%22García-Manau+P%22">García-Manau P</searchLink>; Department of Obstetrics and Gynecology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Cahuana+MJ%22">Cahuana MJ</searchLink>; BCNatal - Barcelona Center for Maternal-Fetal and Neonatal Medicine (Hospital Clínic y Hospital Sant Joan de Deu), Institut Clínic de Ginecología, Obstetrícia I Neonatología, Fetal i+D Fetal Medicine Research Center, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Universidad de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Pérez-Marqués+M%22">Pérez-Marqués M</searchLink>; Department of Obstetrics and Gynecology, Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain.<br /><searchLink fieldCode="AU" term="%22Satorres+E%22">Satorres E</searchLink>; Department of Obstetrics and Gynecology, Hospital Universitari i Politècnic La Fe, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Bugatto+F%22">Bugatto F</searchLink>; Department of Child and Mother Health and Radiology, School of Medicine, University of Cádiz and Division of Maternal and Fetal Medicine, Department of Obstetrics and Gynecology Puerta del Mar University Hospital, Cádiz, Spain.; Biomedical Research and Innovation Institute of Cádiz (INiBICA), Cádiz, Spain.<br /><searchLink fieldCode="AU" term="%22Villalaín+C%22">Villalaín C</searchLink>; Spanish Network in Maternal, Neonatal, Child and Developmental Health Research (RICORS-SAMID), RD24/0013/0015, Instituto de Salud Carlos III, Madrid, Spain.; Department of Obstetrics and Gynecology, Hospital Universitario 12 de Octubre, Madrid, Spain.; Instituto de Investigación Hospital 12 de Octubre (imas12), Madrid, Spain.; Facultad de Medicina, Universidad Complutense de Madrid (UCM), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Robisco+E%22">Robisco E</searchLink>; Department of Obstetrics and Gynecology, Hospital Universitario 12 de Octubre, Madrid, Spain.; Instituto de Investigación Hospital 12 de Octubre (imas12), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22L+Ayala+J%22">L Ayala J</searchLink>; Department of Computer Architecture and Automation, Faculty of Informatics, Complutense University of Madrid, Madrid, Spain.; Spanish Network in Maternal, Neonatal, Child and Developmental Health Research (RICORS-SAMID), RD24/0013/0015, Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Galindo+A%22">Galindo A</searchLink>; Spanish Network in Maternal, Neonatal, Child and Developmental Health Research (RICORS-SAMID), RD24/0013/0015, Instituto de Salud Carlos III, Madrid, Spain.; Department of Obstetrics and Gynecology, Hospital Universitario 12 de Octubre, Madrid, Spain.; Instituto de Investigación Hospital 12 de Octubre (imas12), Madrid, Spain.; Facultad de Medicina, Universidad Complutense de Madrid (UCM), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Herraiz+I%22">Herraiz I</searchLink>; Spanish Network in Maternal, Neonatal, Child and Developmental Health Research (RICORS-SAMID), RD24/0013/0015, Instituto de Salud Carlos III, Madrid, Spain. ignacio.herraiz@salud.madrid.org.; Department of Obstetrics and Gynecology, Hospital Universitario 12 de Octubre, Madrid, Spain. ignacio.herraiz@salud.madrid.org.; Instituto de Investigación Hospital 12 de Octubre (imas12), Madrid, Spain. ignacio.herraiz@salud.madrid.org.; Facultad de Medicina, Universidad Complutense de Madrid (UCM), Madrid, Spain. ignacio.herraiz@salud.madrid.org.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100967799 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1471-2393 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214712393%22">14712393 </searchLink><i>NLM ISO Abbreviation: </i>BMC Pregnancy Childbirth <i>Subsets: </i>MEDLINE
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