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Melatonin and cerium oxide nanoparticles additively mitigate capecitabine-induced hepatotoxicity via targeting oxidative stress, apoptosis, and ERK signaling.

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Title: Melatonin and cerium oxide nanoparticles additively mitigate capecitabine-induced hepatotoxicity via targeting oxidative stress, apoptosis, and ERK signaling.
Authors: Mohany KM; Department of Medical Biochemistry, Faculty of Medicine, Assiut University, Assiut, Egypt. khalidmohany@aun.edu.eg.; Department of Medical Biochemistry, Faculty of Medicine, Merit University, Sohag, Egypt. khalidmohany@aun.edu.eg.; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Assiut University, EL Gammaa, P.O: 71515, Assiut City, Egypt. khalidmohany@aun.edu.eg., Elkady HM; Department of Medical Biochemistry, Faculty of Medicine, Merit University, Sohag, Egypt., Hamad N; Department of Pathology, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt., El-Deek SEM; Department of Medical Biochemistry, Faculty of Medicine, Assiut University, Assiut, Egypt.
Source: BMC pharmacology & toxicology [BMC Pharmacol Toxicol] 2026 Jun 11; Vol. 27 (1). Date of Electronic Publication: 2026 Jun 11.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101590449 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-6511 (Electronic) Linking ISSN: 20506511 NLM ISO Abbreviation: BMC Pharmacol Toxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Melatonin and cerium oxide nanoparticles additively mitigate capecitabine-induced hepatotoxicity via targeting oxidative stress, apoptosis, and ERK signaling.
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  Data: <searchLink fieldCode="AU" term="%22Mohany+KM%22">Mohany KM</searchLink>; Department of Medical Biochemistry, Faculty of Medicine, Assiut University, Assiut, Egypt. khalidmohany@aun.edu.eg.; Department of Medical Biochemistry, Faculty of Medicine, Merit University, Sohag, Egypt. khalidmohany@aun.edu.eg.; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Assiut University, EL Gammaa, P.O: 71515, Assiut City, Egypt. khalidmohany@aun.edu.eg.<br /><searchLink fieldCode="AU" term="%22Elkady+HM%22">Elkady HM</searchLink>; Department of Medical Biochemistry, Faculty of Medicine, Merit University, Sohag, Egypt.<br /><searchLink fieldCode="AU" term="%22Hamad+N%22">Hamad N</searchLink>; Department of Pathology, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt.<br /><searchLink fieldCode="AU" term="%22El-Deek+SEM%22">El-Deek SEM</searchLink>; Department of Medical Biochemistry, Faculty of Medicine, Assiut University, Assiut, Egypt.
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  Data: <searchLink fieldCode="JN" term="%22101590449%22">BMC pharmacology & toxicology</searchLink> [BMC Pharmacol Toxicol] 2026 Jun 11; Vol. 27 (1). <i>Date of Electronic Publication: </i>2026 Jun 11.
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        Value: 10.1186/s40360-026-01150-y
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        Text: English
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              Text: 2026 Jun 11
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