CLEC4G Promotes Pancreatic Cancer Progression by Suppressing Cathepsin B-Mediated Ferroptosis: Evidence From Mendelian Randomization Study and Experimental Validation.
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| Title: | CLEC4G Promotes Pancreatic Cancer Progression by Suppressing Cathepsin B-Mediated Ferroptosis: Evidence From Mendelian Randomization Study and Experimental Validation. |
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| Authors: | Jiang Z; General Surgery, Cancer Center, Department of Gastrointestinal and Pancreatic Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China, hznu.edu.cn.; Key Laboratory of Gastroenterology of Zhejiang Province, Hangzhou, Zhejiang, China., Ma P; General Surgery, Cancer Center, Department of Gastrointestinal and Pancreatic Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China, hznu.edu.cn.; Key Laboratory of Gastroenterology of Zhejiang Province, Hangzhou, Zhejiang, China., Zhang S; State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, cacms.ac.cn., Jin Z; General Surgery, Cancer Center, Department of Gastrointestinal and Pancreatic Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China, hznu.edu.cn., Wang Y; General Surgery, Cancer Center, Department of Gastrointestinal and Pancreatic Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China, hznu.edu.cn.; Key Laboratory of Gastroenterology of Zhejiang Province, Hangzhou, Zhejiang, China., Zhou Y; General Surgery, Cancer Center, Department of Gastrointestinal and Pancreatic Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China, hznu.edu.cn.; Key Laboratory of Gastroenterology of Zhejiang Province, Hangzhou, Zhejiang, China., Zhu Q; General Surgery, Cancer Center, Department of Gastrointestinal and Pancreatic Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China, hznu.edu.cn.; Key Laboratory of Gastroenterology of Zhejiang Province, Hangzhou, Zhejiang, China., Lu C; General Surgery, Cancer Center, Department of Gastrointestinal and Pancreatic Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China, hznu.edu.cn.; Key Laboratory of Gastroenterology of Zhejiang Province, Hangzhou, Zhejiang, China., Tu N; General Surgery, Cancer Center, Department of Gastrointestinal and Pancreatic Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China, hznu.edu.cn., Zhang ZA; General Surgery, Cancer Center, Department of Gastrointestinal and Pancreatic Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China, hznu.edu.cn., Mou Y; General Surgery, Cancer Center, Department of Gastrointestinal and Pancreatic Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China, hznu.edu.cn.; Key Laboratory of Gastroenterology of Zhejiang Province, Hangzhou, Zhejiang, China., Jin W; General Surgery, Cancer Center, Department of Gastrointestinal and Pancreatic Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China, hznu.edu.cn.; Key Laboratory of Gastroenterology of Zhejiang Province, Hangzhou, Zhejiang, China. |
| Source: | Human mutation [Hum Mutat] 2026 Jun 10; Vol. 2026, pp. 7359548. Date of Electronic Publication: 2026 Jun 10 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley-Liss Country of Publication: United States NLM ID: 9215429 Publication Model: eCollection Cited Medium: Internet ISSN: 1098-1004 (Electronic) Linking ISSN: 10597794 NLM ISO Abbreviation: Hum Mutat Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42282992 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: CLEC4G Promotes Pancreatic Cancer Progression by Suppressing Cathepsin B-Mediated Ferroptosis: Evidence From Mendelian Randomization Study and Experimental Validation. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Jiang+Z%22">Jiang Z</searchLink>; General Surgery, Cancer Center, Department of Gastrointestinal and Pancreatic Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China, hznu.edu.cn.; Key Laboratory of Gastroenterology of Zhejiang Province, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Ma+P%22">Ma P</searchLink>; General Surgery, Cancer Center, Department of Gastrointestinal and Pancreatic Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China, hznu.edu.cn.; Key Laboratory of Gastroenterology of Zhejiang Province, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Zhang+S%22">Zhang S</searchLink>; State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, cacms.ac.cn.<br /><searchLink fieldCode="AU" term="%22Jin+Z%22">Jin Z</searchLink>; General Surgery, Cancer Center, Department of Gastrointestinal and Pancreatic Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China, hznu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; General Surgery, Cancer Center, Department of Gastrointestinal and Pancreatic Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China, hznu.edu.cn.; Key Laboratory of Gastroenterology of Zhejiang Province, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Zhou+Y%22">Zhou Y</searchLink>; General Surgery, Cancer Center, Department of Gastrointestinal and Pancreatic Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China, hznu.edu.cn.; Key Laboratory of Gastroenterology of Zhejiang Province, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Zhu+Q%22">Zhu Q</searchLink>; General Surgery, Cancer Center, Department of Gastrointestinal and Pancreatic Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China, hznu.edu.cn.; Key Laboratory of Gastroenterology of Zhejiang Province, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Lu+C%22">Lu C</searchLink>; General Surgery, Cancer Center, Department of Gastrointestinal and Pancreatic Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China, hznu.edu.cn.; Key Laboratory of Gastroenterology of Zhejiang Province, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Tu+N%22">Tu N</searchLink>; General Surgery, Cancer Center, Department of Gastrointestinal and Pancreatic Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China, hznu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Zhang+ZA%22">Zhang ZA</searchLink>; General Surgery, Cancer Center, Department of Gastrointestinal and Pancreatic Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China, hznu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Mou+Y%22">Mou Y</searchLink>; General Surgery, Cancer Center, Department of Gastrointestinal and Pancreatic Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China, hznu.edu.cn.; Key Laboratory of Gastroenterology of Zhejiang Province, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Jin+W%22">Jin W</searchLink>; General Surgery, Cancer Center, Department of Gastrointestinal and Pancreatic Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China, hznu.edu.cn.; Key Laboratory of Gastroenterology of Zhejiang Province, Hangzhou, Zhejiang, China. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229215429%22">Human mutation</searchLink> [Hum Mutat] 2026 Jun 10; Vol. 2026, pp. 7359548. <i>Date of Electronic Publication: </i>2026 Jun 10 (<i>Print Publication: </i>2026). – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-Liss%22">Wiley-Liss </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9215429 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1098-1004 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210597794%22">10597794 </searchLink><i>NLM ISO Abbreviation: </i>Hum Mutat <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42282992 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1155/humu/7359548 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 7359548 Titles: – TitleFull: CLEC4G Promotes Pancreatic Cancer Progression by Suppressing Cathepsin B-Mediated Ferroptosis: Evidence From Mendelian Randomization Study and Experimental Validation. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Jiang Z – PersonEntity: Name: NameFull: Ma P – PersonEntity: Name: NameFull: Zhang S – PersonEntity: Name: NameFull: Jin Z – PersonEntity: Name: NameFull: Wang Y – PersonEntity: Name: NameFull: Zhou Y – PersonEntity: Name: NameFull: Zhu Q – PersonEntity: Name: NameFull: Lu C – PersonEntity: Name: NameFull: Tu N – PersonEntity: Name: NameFull: Zhang ZA – PersonEntity: Name: NameFull: Mou Y – PersonEntity: Name: NameFull: Jin W IsPartOfRelationships: – BibEntity: Dates: – D: 10 M: 06 Text: 2026 Jun 10 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1098-1004 Numbering: – Type: volume Value: 2026 Titles: – TitleFull: Human mutation Type: main |
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