Efficacy and safety profile of volume-staged stereotactic radiosurgery for ruptured, large pediatric arteriovenous malformations: a multicenter cohort analysis.

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Title: Efficacy and safety profile of volume-staged stereotactic radiosurgery for ruptured, large pediatric arteriovenous malformations: a multicenter cohort analysis.
Authors: Shinya Y; 1Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia., Tos SM; 1Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia., Hajikarimloo B; 1Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia., Mantziaris G; 1Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia., Chan JW; Departments of2Radiation Oncology and., Sneed PK; Departments of2Radiation Oncology and., McDermott MW; 3Neurosurgery, University of California, San Francisco, School of Medicine, San Francisco, California., Seymour ZA; 4Department of Radiation Oncology, Beaumont Health, Oakland University William Beaumont School of Medicine, Oakland, California., Grills I; 4Department of Radiation Oncology, Beaumont Health, Oakland University William Beaumont School of Medicine, Oakland, California., Nabeel AM; 5Gamma Knife Center Cairo, Nasser Institute Hospital, Cairo, Egypt.; 6Department of Neurosurgery, Benha University, Qalubya, Egypt., Reda WA; 5Gamma Knife Center Cairo, Nasser Institute Hospital, Cairo, Egypt.; Departments of7Neurosurgery and., Tawadros SR; 5Gamma Knife Center Cairo, Nasser Institute Hospital, Cairo, Egypt.; Departments of7Neurosurgery and., Abdel Karim K; 5Gamma Knife Center Cairo, Nasser Institute Hospital, Cairo, Egypt.; 8Clinical Oncology, Ain Shams University, Cairo, Egypt., El-Shehaby AMN; 5Gamma Knife Center Cairo, Nasser Institute Hospital, Cairo, Egypt.; Departments of7Neurosurgery and., Emad Eldin R; 5Gamma Knife Center Cairo, Nasser Institute Hospital, Cairo, Egypt.; 9Department of Radiation Oncology, National Cancer Institute, Cairo University, Cairo, Egypt., Bin-Alamer O; 10Department of Neurological Surgery, University of Pittsburgh, Pennsylvania., Lunsford LD; 10Department of Neurological Surgery, University of Pittsburgh, Pennsylvania., Niranjan A; 10Department of Neurological Surgery, University of Pittsburgh, Pennsylvania., Peker S; 11Department of Neurosurgery, Koc University School of Medicine, Istanbul, Turkey., Samanci Y; 11Department of Neurosurgery, Koc University School of Medicine, Istanbul, Turkey., Lee CC; 12Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.; 13School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan., Yang HC; 12Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.; 13School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan., Sheehan D; 1Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia., Sheehan K; 1Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia., Liscak R; 14Department of Stereotactic and Radiation Neurosurgery, Na Homolce Hospital, Prague, Czech Republic., Chytka T; 14Department of Stereotactic and Radiation Neurosurgery, Na Homolce Hospital, Prague, Czech Republic., Alzate J; 15Department of Neurosurgery, NYU Langone, New York, New York., Kondziolka D; 15Department of Neurosurgery, NYU Langone, New York, New York., Meng Y; 15Department of Neurosurgery, NYU Langone, New York, New York., Martinez Moreno N; 16Radiosurgery Unit, Hospital Ruber Internacional, Madrid, Spain., Martinez-Álvarez R; 16Radiosurgery Unit, Hospital Ruber Internacional, Madrid, Spain., Hallan DR; 17Department of Neurosurgery, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania., Fritch C; 17Department of Neurosurgery, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania., Jareczek F; 17Department of Neurosurgery, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania., Sciscent BY; 17Department of Neurosurgery, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania., Mathieu D; 18Department of Neurosurgery, Université de Sherbrooke, Centre de recherche du CHUS, Sherbrooke, Quebec, Canada., Carrier L; 18Department of Neurosurgery, Université de Sherbrooke, Centre de recherche du CHUS, Sherbrooke, Quebec, Canada., Abdelsalam A; Departments of19Neurological Surgery and., Starke RM; Departments of19Neurological Surgery and., Benjamin C; Departments of19Neurological Surgery and., Almeida T; 20Radiation Oncology, University of Miami Health System, Miami, Florida., Singh SP; 21Department of Neurosurgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India., Tripathi M; 21Department of Neurosurgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India., Speckter H; 22Dominican Gamma Knife Center and Radiology Department, CEDIMAT, Santo Domingo, Dominican Republic., Lazo E; 22Dominican Gamma Knife Center and Radiology Department, CEDIMAT, Santo Domingo, Dominican Republic., Chen CJ; Departments of23Neurosurgery and., Esquenazi Y; Departments of23Neurosurgery and., Becerril-Gaitan A; Departments of23Neurosurgery and., Amsbaugh MJ; 24Radiation Oncology, The University of Texas Health Science Center, Houston, Texas., Blanco AI; 24Radiation Oncology, The University of Texas Health Science Center, Houston, Texas., Upadhyay R; 25Department of Radiation Oncology, The James Comprehensive Cancer Center Ohio State University, Columbus, Ohio., Palmer JD; 25Department of Radiation Oncology, The James Comprehensive Cancer Center Ohio State University, Columbus, Ohio., Franzini A; 26Department of Neurosurgery, IRCCS Humanitas Research Hospital, Milan, Italy., Picozzi P; 26Department of Neurosurgery, IRCCS Humanitas Research Hospital, Milan, Italy., Lanterna LAA; 27Department of Neurosurgery, ASST Papa Giovanni XXIII Hospital, Bergamo, Italy., Bowden GN; 28Department of Neurosurgery, University of Alberta, Edmonton, Alberta, Canada., Peterson JL; 29Department of Radiation Oncology, Mayo Clinic Florida, Jacksonville, Florida., Chiang VL; 30Department of Neurosurgery, Yale University School of Medicine, New Haven, Connecticut., Pikis S; 1Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia., Xu Z; 1Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia., Sheehan JP; 1Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia.
Source: Journal of neurosurgery. Pediatrics [J Neurosurg Pediatr] 2026 Jun 12, pp. 1-10. Date of Electronic Publication: 2026 Jun 12.
Publication Type: Journal Article
Journal Info: Publisher: American Association of Neurological Surgeons Country of Publication: United States NLM ID: 101463759 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1933-0715 (Electronic) Linking ISSN: 19330707 NLM ISO Abbreviation: J Neurosurg Pediatr Subsets: MEDLINE
Database: MEDLINE Ultimate
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AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: Efficacy and safety profile of volume-staged stereotactic radiosurgery for ruptured, large pediatric arteriovenous malformations: a multicenter cohort analysis.
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  Data: <searchLink fieldCode="AU" term="%22Shinya+Y%22">Shinya Y</searchLink>; 1Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia.<br /><searchLink fieldCode="AU" term="%22Tos+SM%22">Tos SM</searchLink>; 1Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia.<br /><searchLink fieldCode="AU" term="%22Hajikarimloo+B%22">Hajikarimloo B</searchLink>; 1Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia.<br /><searchLink fieldCode="AU" term="%22Mantziaris+G%22">Mantziaris G</searchLink>; 1Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia.<br /><searchLink fieldCode="AU" term="%22Chan+JW%22">Chan JW</searchLink>; Departments of2Radiation Oncology and.<br /><searchLink fieldCode="AU" term="%22Sneed+PK%22">Sneed PK</searchLink>; Departments of2Radiation Oncology and.<br /><searchLink fieldCode="AU" term="%22McDermott+MW%22">McDermott MW</searchLink>; 3Neurosurgery, University of California, San Francisco, School of Medicine, San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Seymour+ZA%22">Seymour ZA</searchLink>; 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11Department of Neurosurgery, Koc University School of Medicine, Istanbul, Turkey.<br /><searchLink fieldCode="AU" term="%22Samanci+Y%22">Samanci Y</searchLink>; 11Department of Neurosurgery, Koc University School of Medicine, Istanbul, Turkey.<br /><searchLink fieldCode="AU" term="%22Lee+CC%22">Lee CC</searchLink>; 12Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.; 13School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yang+HC%22">Yang HC</searchLink>; 12Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.; 13School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Sheehan+D%22">Sheehan D</searchLink>; 1Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia.<br /><searchLink fieldCode="AU" term="%22Sheehan+K%22">Sheehan K</searchLink>; 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            NameFull: Bowden GN
      – PersonEntity:
          Name:
            NameFull: Peterson JL
      – PersonEntity:
          Name:
            NameFull: Chiang VL
      – PersonEntity:
          Name:
            NameFull: Pikis S
      – PersonEntity:
          Name:
            NameFull: Xu Z
      – PersonEntity:
          Name:
            NameFull: Sheehan JP
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 12
              M: 06
              Text: 2026 Jun 12
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1933-0715
          Titles:
            – TitleFull: Journal of neurosurgery. Pediatrics
              Type: main
ResultId 1