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Response to "Concerns Regarding Model Robustness and Clinical Generalizability in the Proposed Nomogram for Osteoradionecrosis After Fibula Free Flap Reconstruction".

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Title: Response to "Concerns Regarding Model Robustness and Clinical Generalizability in the Proposed Nomogram for Osteoradionecrosis After Fibula Free Flap Reconstruction".
Authors: Costantino A; Otorhinolaryngology Unit, IRCCS Humanitas Research Hospital, Milan, Italy., Festa B; Otorhinolaryngology Unit, IRCCS Humanitas Research Hospital, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Milan, Italy., Marchi F; Unit of Otorhinolaryngology-Head and Neck Surgery, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy., Tsao CK; Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital & Chang Gung University College of Medicine, Taoyuan, Taiwan.; Center for Tissue Engineering, Chang Gung Memorial Hospital, Taoyuan, Taiwan., Pellini R; Department of Otorhinolaryngology-Head and Neck Surgery, IRCCS Regina Elena National Cancer Institute, Rome, Italy., Gazzini L; Department of Otolaryngology Head and Neck Surgery, Hospital of Bolzano (SABES-ASDAA), Bolzano, Italy.; Teaching Hospital of the Paracelsus Medical Private University (PMU), Bolzano, Italy., Dzięgielewski PT; Department of Otolaryngology, University of Florida, Gainesville, Florida, USA., Ciniglio M; Department of Otorhinolaryngology, Head and Neck Surgery, USL Toscana Centro, Prato, Italy., Mazzola F; Department of Otorhinolaryngology-Head and Neck Surgery, IRCCS Regina Elena National Cancer Institute, Rome, Italy., Calabrese L; Department of Otolaryngology Head and Neck Surgery, Hospital of Bolzano (SABES-ASDAA), Bolzano, Italy.; Teaching Hospital of the Paracelsus Medical Private University (PMU), Bolzano, Italy., Sarno A; Department of Otorhinolaryngology, Head and Neck Surgery, USL Toscana Centro, Prato, Italy., Parrinello G; Unit of Otorhinolaryngology-Head and Neck Surgery, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Chow L; Albert Einstein College of Medicine, New York, New York, USA., Chen JK; Department of Oral and Maxillofacial Surgery, Chang Gung Memorial Hospital, Taipei, Taiwan., Peretti G; Unit of Otorhinolaryngology-Head and Neck Surgery, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy., De Virgilio A; Department of Organs of Sense, 'Sapienza' University of Rome, Rome, Italy.
Source: Head & neck [Head Neck] 2026 Jun 12. Date of Electronic Publication: 2026 Jun 12.
Publication Type: Letter
Journal Info: Publisher: John Wiley And Sons Country of Publication: United States NLM ID: 8902541 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0347 (Electronic) Linking ISSN: 10433074 NLM ISO Abbreviation: Head Neck Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Editorial & Opinion
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  Data: Response to "Concerns Regarding Model Robustness and Clinical Generalizability in the Proposed Nomogram for Osteoradionecrosis After Fibula Free Flap Reconstruction".
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  Data: <searchLink fieldCode="AU" term="%22Costantino+A%22">Costantino A</searchLink>; Otorhinolaryngology Unit, IRCCS Humanitas Research Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Festa+B%22">Festa B</searchLink>; Otorhinolaryngology Unit, IRCCS Humanitas Research Hospital, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Marchi+F%22">Marchi F</searchLink>; Unit of Otorhinolaryngology-Head and Neck Surgery, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Tsao+CK%22">Tsao CK</searchLink>; Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital & Chang Gung University College of Medicine, Taoyuan, Taiwan.; Center for Tissue Engineering, Chang Gung Memorial Hospital, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Pellini+R%22">Pellini R</searchLink>; Department of Otorhinolaryngology-Head and Neck Surgery, IRCCS Regina Elena National Cancer Institute, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Gazzini+L%22">Gazzini L</searchLink>; Department of Otolaryngology Head and Neck Surgery, Hospital of Bolzano (SABES-ASDAA), Bolzano, Italy.; Teaching Hospital of the Paracelsus Medical Private University (PMU), Bolzano, Italy.<br /><searchLink fieldCode="AU" term="%22Dzięgielewski+PT%22">Dzięgielewski PT</searchLink>; Department of Otolaryngology, University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Ciniglio+M%22">Ciniglio M</searchLink>; Department of Otorhinolaryngology, Head and Neck Surgery, USL Toscana Centro, Prato, Italy.<br /><searchLink fieldCode="AU" term="%22Mazzola+F%22">Mazzola F</searchLink>; Department of Otorhinolaryngology-Head and Neck Surgery, IRCCS Regina Elena National Cancer Institute, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Calabrese+L%22">Calabrese L</searchLink>; Department of Otolaryngology Head and Neck Surgery, Hospital of Bolzano (SABES-ASDAA), Bolzano, Italy.; Teaching Hospital of the Paracelsus Medical Private University (PMU), Bolzano, Italy.<br /><searchLink fieldCode="AU" term="%22Sarno+A%22">Sarno A</searchLink>; Department of Otorhinolaryngology, Head and Neck Surgery, USL Toscana Centro, Prato, Italy.<br /><searchLink fieldCode="AU" term="%22Parrinello+G%22">Parrinello G</searchLink>; Unit of Otorhinolaryngology-Head and Neck Surgery, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Chow+L%22">Chow L</searchLink>; Albert Einstein College of Medicine, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Chen+JK%22">Chen JK</searchLink>; Department of Oral and Maxillofacial Surgery, Chang Gung Memorial Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Peretti+G%22">Peretti G</searchLink>; Unit of Otorhinolaryngology-Head and Neck Surgery, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22De+Virgilio+A%22">De Virgilio A</searchLink>; Department of Organs of Sense, 'Sapienza' University of Rome, Rome, Italy.
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        Text: English
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      – TitleFull: Response to "Concerns Regarding Model Robustness and Clinical Generalizability in the Proposed Nomogram for Osteoradionecrosis After Fibula Free Flap Reconstruction".
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              Text: 2026 Jun 12
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