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Regional sex differences in human cortical anatomy vary in their morphometric bases and overlap with sex chromosomal and gonadal influences.

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Title: Regional sex differences in human cortical anatomy vary in their morphometric bases and overlap with sex chromosomal and gonadal influences.
Authors: Lee HM; Section on Developmental Neurogenomics, National Institute of Mental Health, Bethesda, MD, USA., Liu S; Section on Developmental Neurogenomics, National Institute of Mental Health, Bethesda, MD, USA., Guma E; Section on Developmental Neurogenomics, National Institute of Mental Health, Bethesda, MD, USA.; Department of Pediatrics, Massachusetts General Hospital, Boston, MA, USA., Levitis E; Section on Developmental Neurogenomics, National Institute of Mental Health, Bethesda, MD, USA.; Center for Medical Image Computing, Department of Computer Science, University College London, London, UK.; Department of Child and Adolescent Psychiatry and Behavioral Science, The Children's Hospital of Philadelphia, Philadelphia, PA, USA., Shafee R; Section on Developmental Neurogenomics, National Institute of Mental Health, Bethesda, MD, USA., Dugan G; Section on Developmental Neurogenomics, National Institute of Mental Health, Bethesda, MD, USA., Lalonde FM; Section on Developmental Neurogenomics, National Institute of Mental Health, Bethesda, MD, USA., Clasen L; Section on Developmental Neurogenomics, National Institute of Mental Health, Bethesda, MD, USA., DeCasien A; Section on Developmental Neurogenomics, National Institute of Mental Health, Bethesda, MD, USA.; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD, USA., Chakravarty MM; Department of Psychiatry, McGill University, Montreal, QC, Canada.; Cerebral Imaging Centre, Douglas Research Centre, Montreal, QC, Canada., Lerch JP; Mouse Imaging Centre, Toronto, ON, Canada.; The Hospital for Sick Children, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.; Wellcome Centre for Integrative Neuroimaging, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK., Wagstyl K; School of Biomedical Engineering & Imaging Sciences, King's College London, London, UK.; UCL Great Ormond Street Institute of Child Health, London, UK., Delaney A; Division of Endocrinology, Department of Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, USA., Raznahan A; Section on Developmental Neurogenomics, National Institute of Mental Health, Bethesda, MD, USA. raznahana@mail.nih.gov.
Source: Nature communications [Nat Commun] 2026 Jun 13. Date of Electronic Publication: 2026 Jun 13.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Lee+HM%22">Lee HM</searchLink>; Section on Developmental Neurogenomics, National Institute of Mental Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Liu+S%22">Liu S</searchLink>; Section on Developmental Neurogenomics, National Institute of Mental Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Guma+E%22">Guma E</searchLink>; Section on Developmental Neurogenomics, National Institute of Mental Health, Bethesda, MD, USA.; Department of Pediatrics, Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Levitis+E%22">Levitis E</searchLink>; Section on Developmental Neurogenomics, National Institute of Mental Health, Bethesda, MD, USA.; Center for Medical Image Computing, Department of Computer Science, University College London, London, UK.; Department of Child and Adolescent Psychiatry and Behavioral Science, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Shafee+R%22">Shafee R</searchLink>; Section on Developmental Neurogenomics, National Institute of Mental Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Dugan+G%22">Dugan G</searchLink>; Section on Developmental Neurogenomics, National Institute of Mental Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Lalonde+FM%22">Lalonde FM</searchLink>; Section on Developmental Neurogenomics, National Institute of Mental Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Clasen+L%22">Clasen L</searchLink>; Section on Developmental Neurogenomics, National Institute of Mental Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22DeCasien+A%22">DeCasien A</searchLink>; Section on Developmental Neurogenomics, National Institute of Mental Health, Bethesda, MD, USA.; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Chakravarty+MM%22">Chakravarty MM</searchLink>; Department of Psychiatry, McGill University, Montreal, QC, Canada.; Cerebral Imaging Centre, Douglas Research Centre, Montreal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Lerch+JP%22">Lerch JP</searchLink>; Mouse Imaging Centre, Toronto, ON, Canada.; The Hospital for Sick Children, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.; Wellcome Centre for Integrative Neuroimaging, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Wagstyl+K%22">Wagstyl K</searchLink>; School of Biomedical Engineering & Imaging Sciences, King's College London, London, UK.; UCL Great Ormond Street Institute of Child Health, London, UK.<br /><searchLink fieldCode="AU" term="%22Delaney+A%22">Delaney A</searchLink>; Division of Endocrinology, Department of Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Raznahan+A%22">Raznahan A</searchLink>; Section on Developmental Neurogenomics, National Institute of Mental Health, Bethesda, MD, USA. raznahana@mail.nih.gov.
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