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Symptom-linked disruption of the vaginal Lactobacillus-IL-2/IFN-γ axis in genitourinary syndrome of menopause related symptoms.

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Title: Symptom-linked disruption of the vaginal Lactobacillus-IL-2/IFN-γ axis in genitourinary syndrome of menopause related symptoms.
Authors: Kim H; Department of Obstetrics and Gynecology, Severance Hospital, Yonsei University College of Medicine, Institute for Innovation in Digital Healthcare, Yonsei University, Seoul, Republic of Korea.; Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Republic of Korea., Choi J; Institute for Immunology and Immunological Disease, Yonsei University College of Medicine, Seoul, Republic of Korea., Hitayezu E; Center for Natural Product Systems Biology, Korea Institute of Science and Technology (KIST), Gangneung, 25451, Republic of Korea.; Department of Food Science, College of Life Sciences, Gangneung-Wonju National University, Gangneung, Republic of Korea., Chang L; Department of Microbiology and Immunology, Graduate School of Medical Science, Yonsei University College of Medicine, Brain Korea21 Project, Seoul, Republic of Korea., Chung YS; Department of Obstetrics and Gynecology, Severance Hospital, Yonsei University College of Medicine, Institute for Innovation in Digital Healthcare, Yonsei University, Seoul, Republic of Korea.; Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Republic of Korea., Baek JK; Department of Obstetrics and Gynecology, Severance Hospital, Yonsei University College of Medicine, Institute for Innovation in Digital Healthcare, Yonsei University, Seoul, Republic of Korea.; Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Republic of Korea., Yun BH; Department of Obstetrics and Gynecology, Severance Hospital, Yonsei University College of Medicine, Institute for Innovation in Digital Healthcare, Yonsei University, Seoul, Republic of Korea.; Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Republic of Korea., Cha KH; Center for Natural Product Systems Biology, Korea Institute of Science and Technology (KIST), Gangneung, 25451, Republic of Korea. chakh79@kist.re.kr.; Natural Product Applied Science, KIST School, University of Science and Technology, Gangneung, Republic of Korea. chakh79@kist.re.kr., Seo SK; Department of Obstetrics and Gynecology, Severance Hospital, Yonsei University College of Medicine, Institute for Innovation in Digital Healthcare, Yonsei University, Seoul, Republic of Korea. tudeolseo@yuhs.ac.; Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Republic of Korea. tudeolseo@yuhs.ac., Kwon HK; Institute for Immunology and Immunological Disease, Yonsei University College of Medicine, Seoul, Republic of Korea. HK@yuhs.ac.; Department of Microbiology and Immunology, Graduate School of Medical Science, Yonsei University College of Medicine, Brain Korea21 Project, Seoul, Republic of Korea. HK@yuhs.ac.
Source: Scientific reports [Sci Rep] 2026 Jun 14. Date of Electronic Publication: 2026 Jun 14.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Kim+H%22">Kim H</searchLink>; Department of Obstetrics and Gynecology, Severance Hospital, Yonsei University College of Medicine, Institute for Innovation in Digital Healthcare, Yonsei University, Seoul, Republic of Korea.; Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+J%22">Choi J</searchLink>; Institute for Immunology and Immunological Disease, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Hitayezu+E%22">Hitayezu E</searchLink>; Center for Natural Product Systems Biology, Korea Institute of Science and Technology (KIST), Gangneung, 25451, Republic of Korea.; Department of Food Science, College of Life Sciences, Gangneung-Wonju National University, Gangneung, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Chang+L%22">Chang L</searchLink>; Department of Microbiology and Immunology, Graduate School of Medical Science, Yonsei University College of Medicine, Brain Korea21 Project, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Chung+YS%22">Chung YS</searchLink>; Department of Obstetrics and Gynecology, Severance Hospital, Yonsei University College of Medicine, Institute for Innovation in Digital Healthcare, Yonsei University, Seoul, Republic of Korea.; Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Baek+JK%22">Baek JK</searchLink>; Department of Obstetrics and Gynecology, Severance Hospital, Yonsei University College of Medicine, Institute for Innovation in Digital Healthcare, Yonsei University, Seoul, Republic of Korea.; Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yun+BH%22">Yun BH</searchLink>; Department of Obstetrics and Gynecology, Severance Hospital, Yonsei University College of Medicine, Institute for Innovation in Digital Healthcare, Yonsei University, Seoul, Republic of Korea.; Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Cha+KH%22">Cha KH</searchLink>; Center for Natural Product Systems Biology, Korea Institute of Science and Technology (KIST), Gangneung, 25451, Republic of Korea. chakh79@kist.re.kr.; Natural Product Applied Science, KIST School, University of Science and Technology, Gangneung, Republic of Korea. chakh79@kist.re.kr.<br /><searchLink fieldCode="AU" term="%22Seo+SK%22">Seo SK</searchLink>; Department of Obstetrics and Gynecology, Severance Hospital, Yonsei University College of Medicine, Institute for Innovation in Digital Healthcare, Yonsei University, Seoul, Republic of Korea. tudeolseo@yuhs.ac.; Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Republic of Korea. tudeolseo@yuhs.ac.<br /><searchLink fieldCode="AU" term="%22Kwon+HK%22">Kwon HK</searchLink>; Institute for Immunology and Immunological Disease, Yonsei University College of Medicine, Seoul, Republic of Korea. HK@yuhs.ac.; Department of Microbiology and Immunology, Graduate School of Medical Science, Yonsei University College of Medicine, Brain Korea21 Project, Seoul, Republic of Korea. HK@yuhs.ac.
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              Text: 2026 Jun 14
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