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A self-amplifying RNA vector based on rubella virus for mRNA therapeutics and vaccine applications.

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Title: A self-amplifying RNA vector based on rubella virus for mRNA therapeutics and vaccine applications.
Authors: Jing M; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 636921, Singapore.; NTU Institute of Structural Biology, Nanyang Technological University, Singapore 636921, Singapore., Law MCY; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 636921, Singapore.; NTU Institute of Structural Biology, Nanyang Technological University, Singapore 636921, Singapore.; National Institute of Allergy and Infectious Diseases, Rockville, MD 20852, USA., Phung CD; Department of Pharmacology and Institute for Digital Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117600, Singapore.; Washington University School of Medicine, Washington University in St Louis, St. Louis 63110, Missouri, USA., He Y; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 636921, Singapore.; NTU Institute of Structural Biology, Nanyang Technological University, Singapore 636921, Singapore.; Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, Sichuan 611130, China., Tan YB; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 636921, Singapore.; NTU Institute of Structural Biology, Nanyang Technological University, Singapore 636921, Singapore.; Thrixen, Singapore 138567, Singapore., Le MTN; Department of Pharmacology and Institute for Digital Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117600, Singapore.; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.; Institute of Molecular and Cell Biology, A∗STAR, Singapore 138673, Singapore., Luo D; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 636921, Singapore.; NTU Institute of Structural Biology, Nanyang Technological University, Singapore 636921, Singapore.; National Centre for Infectious Diseases, Singapore 308442, Singapore.
Source: Molecular therapy. Nucleic acids [Mol Ther Nucleic Acids] 2026 May 25; Vol. 37 (2), pp. 102967. Date of Electronic Publication: 2026 May 25 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101581621 Publication Model: eCollection Cited Medium: Print ISSN: 2162-2531 (Print) Linking ISSN: 21622531 NLM ISO Abbreviation: Mol Ther Nucleic Acids Subsets: PubMed not MEDLINE
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  Data: A self-amplifying RNA vector based on rubella virus for mRNA therapeutics and vaccine applications.
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  Data: <searchLink fieldCode="AU" term="%22Jing+M%22">Jing M</searchLink>; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 636921, Singapore.; NTU Institute of Structural Biology, Nanyang Technological University, Singapore 636921, Singapore.<br /><searchLink fieldCode="AU" term="%22Law+MCY%22">Law MCY</searchLink>; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 636921, Singapore.; NTU Institute of Structural Biology, Nanyang Technological University, Singapore 636921, Singapore.; National Institute of Allergy and Infectious Diseases, Rockville, MD 20852, USA.<br /><searchLink fieldCode="AU" term="%22Phung+CD%22">Phung CD</searchLink>; Department of Pharmacology and Institute for Digital Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117600, Singapore.; Washington University School of Medicine, Washington University in St Louis, St. Louis 63110, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22He+Y%22">He Y</searchLink>; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 636921, Singapore.; NTU Institute of Structural Biology, Nanyang Technological University, Singapore 636921, Singapore.; Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, Sichuan 611130, China.<br /><searchLink fieldCode="AU" term="%22Tan+YB%22">Tan YB</searchLink>; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 636921, Singapore.; NTU Institute of Structural Biology, Nanyang Technological University, Singapore 636921, Singapore.; Thrixen, Singapore 138567, Singapore.<br /><searchLink fieldCode="AU" term="%22Le+MTN%22">Le MTN</searchLink>; Department of Pharmacology and Institute for Digital Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117600, Singapore.; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.; Institute of Molecular and Cell Biology, A∗STAR, Singapore 138673, Singapore.<br /><searchLink fieldCode="AU" term="%22Luo+D%22">Luo D</searchLink>; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 636921, Singapore.; NTU Institute of Structural Biology, Nanyang Technological University, Singapore 636921, Singapore.; National Centre for Infectious Diseases, Singapore 308442, Singapore.
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  Data: <searchLink fieldCode="JN" term="%22101581621%22">Molecular therapy. Nucleic acids</searchLink> [Mol Ther Nucleic Acids] 2026 May 25; Vol. 37 (2), pp. 102967. <i>Date of Electronic Publication: </i>2026 May 25 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101581621 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2162-2531 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221622531%22">21622531 </searchLink><i>NLM ISO Abbreviation: </i>Mol Ther Nucleic Acids <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1016/j.omtn.2026.102967
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        Text: English
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              Text: 2026 May 25
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