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Impact of high versus low fraction of inspired oxygen for anaesthetic washout and extubation on postoperative pulmonary atelectasis formation and oxygenation: a randomised controlled trial.

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Title: Impact of high versus low fraction of inspired oxygen for anaesthetic washout and extubation on postoperative pulmonary atelectasis formation and oxygenation: a randomised controlled trial.
Authors: Paschold BS; Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA, USA; Center for Anesthesia Research Excellence, Harvard Medical School, Boston, MA, USA; Department of Anaesthesiology and Intensive Care Medicine, Faculty of Medicine, Ulm University, Ulm, Germany., Braeuer BLP; Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA, USA; Center for Anesthesia Research Excellence, Harvard Medical School, Boston, MA, USA., Santer P; Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA, USA., Wichelhaus LM; Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA, USA; Center for Anesthesia Research Excellence, Harvard Medical School, Boston, MA, USA., Alcala G; Department of Medicine, Division of Respirology, University Health Network, Toronto, ON, Canada; Unidade de Terapia Intensiva Respiratoria, Divisao de Pulmonologia, Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Fasculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil., Robitaille MJ; Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA, USA., Woloszynek S; Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA, USA., Pinciroli R; Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA, USA., Sahli S; Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA, USA; Center for Anesthesia Research Excellence, Harvard Medical School, Boston, MA, USA; Institute of Anaesthesiology, University Hospital Zurich, Zurich, Switzerland., Wachtendorf LJ; Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA, USA; Center for Anesthesia Research Excellence, Harvard Medical School, Boston, MA, USA., Karimitar A; Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA, USA., Goodspeed V; Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA, USA; Center for Anesthesia Research Excellence, Harvard Medical School, Boston, MA, USA., Pensier J; Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA, USA; Center for Anesthesia Research Excellence, Harvard Medical School, Boston, MA, USA; Anaesthesiology and Intensive Care, Anaesthesia and Critical Care Department B, Saint Eloi Teaching Hospital, PhyMedExp, University of Montpellier, INSERM U1046, Montpellier, France., Jungwirth B; Department of Anaesthesiology and Intensive Care Medicine, Faculty of Medicine, Ulm University, Ulm, Germany., Baedorf-Kassis E; Center for Anesthesia Research Excellence, Harvard Medical School, Boston, MA, USA; Division of Pulmonary and Critical Care Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA., Amato MBP; Center for Anesthesia Research Excellence, Harvard Medical School, Boston, MA, USA; Unidade de Terapia Intensiva Respiratoria, Divisao de Pulmonologia, Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Fasculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil., Talmor D; Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA, USA; Center for Anesthesia Research Excellence, Harvard Medical School, Boston, MA, USA., Schaefer MS; Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA, USA; Center for Anesthesia Research Excellence, Harvard Medical School, Boston, MA, USA. Electronic address: msschaef@bidmc.harvard.edu.
Source: British journal of anaesthesia [Br J Anaesth] 2026 Jun 15. Date of Electronic Publication: 2026 Jun 15.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 0372541 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-6771 (Electronic) Linking ISSN: 00070912 NLM ISO Abbreviation: Br J Anaesth Subsets: MEDLINE
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  Data: Impact of high versus low fraction of inspired oxygen for anaesthetic washout and extubation on postoperative pulmonary atelectasis formation and oxygenation: a randomised controlled trial.
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  Data: <searchLink fieldCode="AU" term="%22Paschold+BS%22">Paschold BS</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA, USA; Center for Anesthesia Research Excellence, Harvard Medical School, Boston, MA, USA; Department of Anaesthesiology and Intensive Care Medicine, Faculty of Medicine, Ulm University, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Braeuer+BLP%22">Braeuer BLP</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA, USA; Center for Anesthesia Research Excellence, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Santer+P%22">Santer P</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Wichelhaus+LM%22">Wichelhaus LM</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA, USA; Center for Anesthesia Research Excellence, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Alcala+G%22">Alcala G</searchLink>; Department of Medicine, Division of Respirology, University Health Network, Toronto, ON, Canada; Unidade de Terapia Intensiva Respiratoria, Divisao de Pulmonologia, Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Fasculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Robitaille+MJ%22">Robitaille MJ</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Woloszynek+S%22">Woloszynek S</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Pinciroli+R%22">Pinciroli R</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Sahli+S%22">Sahli S</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA, USA; Center for Anesthesia Research Excellence, Harvard Medical School, Boston, MA, USA; Institute of Anaesthesiology, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Wachtendorf+LJ%22">Wachtendorf LJ</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA, USA; Center for Anesthesia Research Excellence, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Karimitar+A%22">Karimitar A</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Goodspeed+V%22">Goodspeed V</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA, USA; Center for Anesthesia Research Excellence, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Pensier+J%22">Pensier J</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA, USA; Center for Anesthesia Research Excellence, Harvard Medical School, Boston, MA, USA; Anaesthesiology and Intensive Care, Anaesthesia and Critical Care Department B, Saint Eloi Teaching Hospital, PhyMedExp, University of Montpellier, INSERM U1046, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Jungwirth+B%22">Jungwirth B</searchLink>; Department of Anaesthesiology and Intensive Care Medicine, Faculty of Medicine, Ulm University, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Baedorf-Kassis+E%22">Baedorf-Kassis E</searchLink>; Center for Anesthesia Research Excellence, Harvard Medical School, Boston, MA, USA; Division of Pulmonary and Critical Care Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Amato+MBP%22">Amato MBP</searchLink>; Center for Anesthesia Research Excellence, Harvard Medical School, Boston, MA, USA; Unidade de Terapia Intensiva Respiratoria, Divisao de Pulmonologia, Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Fasculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Talmor+D%22">Talmor D</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA, USA; Center for Anesthesia Research Excellence, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Schaefer+MS%22">Schaefer MS</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA, USA; Center for Anesthesia Research Excellence, Harvard Medical School, Boston, MA, USA. Electronic address: msschaef@bidmc.harvard.edu.
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        Value: 10.1016/j.bja.2026.04.056
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              Text: 2026 Jun 15
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