Mechanisms of increased Alzheimer's disease pathology with R47H and R62H TREM2 variants.
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| Title: | Mechanisms of increased Alzheimer's disease pathology with R47H and R62H TREM2 variants. |
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| Authors: | Fancy NN; UK Dementia Research Institute at Imperial College, London, UK.; Department of Brain Sciences, Imperial College London, London, UK., Willumsen N; UK Dementia Research Institute at Imperial College, London, UK.; Department of Brain Sciences, Imperial College London, London, UK., Chau VMN; UK Dementia Research Institute at Imperial College, London, UK.; Department of Brain Sciences, Imperial College London, London, UK., Boulger SL; UK Dementia Research Institute at Imperial College, London, UK.; Department of Brain Sciences, Imperial College London, London, UK., Whitwell HJ; Department of Metabolism, Digestion and Reproduction, Section of Bioanalytical Chemistry, Division of Systems Medicine, Sir Alexander Fleming Building, Imperial College London, London, UK.; Department of Metabolism, Digestion and Reproduction, National Phenome Centre and Imperial Clinical Phenotyping Centre, Imperial College London, London, UK., Wang W; Department of Metabolism, Digestion and Reproduction, Section of Bioanalytical Chemistry, Division of Systems Medicine, Sir Alexander Fleming Building, Imperial College London, London, UK.; Department of Metabolism, Digestion and Reproduction, National Phenome Centre and Imperial Clinical Phenotyping Centre, Imperial College London, London, UK., Avot B; UK Dementia Research Institute at Imperial College, London, UK.; Department of Brain Sciences, Imperial College London, London, UK., Thomas M; UK Dementia Research Institute at Imperial College, London, UK.; Department of Brain Sciences, Imperial College London, London, UK., Talbot-Martin J; UK Dementia Research Institute at Imperial College, London, UK.; Department of Brain Sciences, Imperial College London, London, UK., Tsartsalis S; Department of Psychiatry, University Hospitals of Geneva, Switzerland+ Centre for Psychiatric Neuroscience, Lausanne University Hospitals, Lausanne, Switzerland., Khozoie C; UK Dementia Research Institute at Imperial College, London, UK.; Department of Brain Sciences, Imperial College London, London, UK., McGarry A; UK Dementia Research Institute at Imperial College, London, UK.; Department of Brain Sciences, Imperial College London, London, UK.; Department of Basic and Clinical Neuroscience, Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK., Schneegans E; UK Dementia Research Institute at Imperial College, London, UK.; Department of Brain Sciences, Imperial College London, London, UK., Yagoubi R; UK Dementia Research Institute at Imperial College, London, UK.; Department of Brain Sciences, Imperial College London, London, UK., Cheung TKD; UK Dementia Research Institute at Imperial College, London, UK.; Department of Brain Sciences, Imperial College London, London, UK., Papageorgopoulou M; UK Dementia Research Institute at Imperial College, London, UK.; Department of Brain Sciences, Imperial College London, London, UK., Adair E; UK Dementia Research Institute at Imperial College, London, UK.; Department of Brain Sciences, Imperial College London, London, UK., Cooper B; Department of Metabolism, Digestion and Reproduction, National Phenome Centre and Imperial Clinical Phenotyping Centre, Imperial College London, London, UK., Davey K; UK Dementia Research Institute at Imperial College, London, UK.; Department of Brain Sciences, Imperial College London, London, UK.; Department of Basic and Clinical Neuroscience, Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK.; UK Dementia Research Institute at King's College London, London, UK., Smith AM; UK Dementia Research Institute at Imperial College, London, UK.; Department of Brain Sciences, Imperial College London, London, UK.; Department of Pharmacology and Clinical Pharmacology and Centre for Brain Research, University of Auckland, Auckland, New Zealand., Scotton W; Department of Neurodegenerative Disease, University College London (UCL) Institute of Neurology, London, UK.; Department of Biomedical Sciences, School of Infection, Inflammation and Immunology, College of Medicine and Health, University of Birmingham, Birmingham, UK., Hardy J; Department of Neurodegenerative Disease, University College London (UCL) Institute of Neurology, London, UK., Matthews PM; UK Dementia Research Institute at Imperial College, London, UK. p.matthews@imperial.ac.uk.; Department of Brain Sciences, Imperial College London, London, UK. p.matthews@imperial.ac.uk.; Rosalind Franklin Institute, Harwell Science and Innovation Campus, Didcot, Oxon, UK. p.matthews@imperial.ac.uk., Jackson JS; UK Dementia Research Institute at Imperial College, London, UK. johanna.jackson@imperial.ac.uk.; Department of Brain Sciences, Imperial College London, London, UK. johanna.jackson@imperial.ac.uk. |
| Source: | Acta neuropathologica [Acta Neuropathol] 2026 Jun 15; Vol. 151 (1). Date of Electronic Publication: 2026 Jun 15. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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