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Glycosylated extracellular matrix drives immune suppression by modulating macrophage-T cell crosstalk in triple-negative breast cancer.

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Title: Glycosylated extracellular matrix drives immune suppression by modulating macrophage-T cell crosstalk in triple-negative breast cancer.
Authors: Tarantola L; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK., Tyler EJ; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK., Liu Y; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK., Maniati E; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK., Thornton KA; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK., Martín-Otal C; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK., Hanna D; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK., Kumar R; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK., Gauthier V; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK., Hirani P; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK., Burger Ramos M; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK., Roth NJ; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK., Bragg J; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK., Puttock EH; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK., McDermott J; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK., Rajeeve V; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK., Cutillas P; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK., Maiques O; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK., Soulier A; Neobe Therapeutics, Salisbury House, Station Road, Cambridge, UK., Correa de Sampaio P; Neobe Therapeutics, Salisbury House, Station Road, Cambridge, UK., Jones LJ; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK., Davies DM; Leucid Bio, Guy's Hospital, Great Maze Pond, London, UK., Maher J; Leucid Bio, Guy's Hospital, Great Maze Pond, London, UK., Haslam SM; Department of Life Sciences, Imperial College London, London, UK., Läubli H; Department of Biomedicine and Division of Medical Oncology, University Hospital Basel, Basel, Switzerland., Pearce OMT; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK. o.pearce@qmul.ac.uk.
Source: Nature communications [Nat Commun] 2026 Jun 16; Vol. 17 (1). Date of Electronic Publication: 2026 Jun 16.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Glycosylated extracellular matrix drives immune suppression by modulating macrophage-T cell crosstalk in triple-negative breast cancer.
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  Data: <searchLink fieldCode="AU" term="%22Tarantola+L%22">Tarantola L</searchLink>; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Tyler+EJ%22">Tyler EJ</searchLink>; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Maniati+E%22">Maniati E</searchLink>; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Thornton+KA%22">Thornton KA</searchLink>; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Martín-Otal+C%22">Martín-Otal C</searchLink>; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Hanna+D%22">Hanna D</searchLink>; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Kumar+R%22">Kumar R</searchLink>; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Gauthier+V%22">Gauthier V</searchLink>; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Hirani+P%22">Hirani P</searchLink>; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Burger+Ramos+M%22">Burger Ramos M</searchLink>; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Roth+NJ%22">Roth NJ</searchLink>; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Bragg+J%22">Bragg J</searchLink>; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Puttock+EH%22">Puttock EH</searchLink>; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22McDermott+J%22">McDermott J</searchLink>; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Rajeeve+V%22">Rajeeve V</searchLink>; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Cutillas+P%22">Cutillas P</searchLink>; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Maiques+O%22">Maiques O</searchLink>; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Soulier+A%22">Soulier A</searchLink>; Neobe Therapeutics, Salisbury House, Station Road, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Correa+de+Sampaio+P%22">Correa de Sampaio P</searchLink>; Neobe Therapeutics, Salisbury House, Station Road, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Jones+LJ%22">Jones LJ</searchLink>; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Davies+DM%22">Davies DM</searchLink>; Leucid Bio, Guy's Hospital, Great Maze Pond, London, UK.<br /><searchLink fieldCode="AU" term="%22Maher+J%22">Maher J</searchLink>; Leucid Bio, Guy's Hospital, Great Maze Pond, London, UK.<br /><searchLink fieldCode="AU" term="%22Haslam+SM%22">Haslam SM</searchLink>; Department of Life Sciences, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Läubli+H%22">Läubli H</searchLink>; Department of Biomedicine and Division of Medical Oncology, University Hospital Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Pearce+OMT%22">Pearce OMT</searchLink>; Queen Mary University of London, Barts Cancer Institute, John Vane Science Centre, London, UK. o.pearce@qmul.ac.uk.
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