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Redox-regulated in situ-forming hydrogel informed by single-cell transcriptomics for functional restoration of injured vocal folds.

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Title: Redox-regulated in situ-forming hydrogel informed by single-cell transcriptomics for functional restoration of injured vocal folds.
Authors: Xiong M; Department of Otolaryngology-Head & Neck Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China.; Department of Orthopedic Surgery and Orthopedic Research Institute, Stem Cell and Tissue Engineering Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China., Zou CY; Department of Orthopedic Surgery and Orthopedic Research Institute, Stem Cell and Tissue Engineering Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China.; Tianfu Jincheng Laboratory, Chengdu, Sichuan, PR China., Zhao L; Department of Hematology and Institute of Hematology, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China., Jiang YL; Department of Orthopedic Surgery and Orthopedic Research Institute, Stem Cell and Tissue Engineering Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China.; Tianfu Jincheng Laboratory, Chengdu, Sichuan, PR China., Li QJ; Department of Orthopedic Surgery and Orthopedic Research Institute, Stem Cell and Tissue Engineering Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China.; Tianfu Jincheng Laboratory, Chengdu, Sichuan, PR China., Fan MH; Department of Orthopedic Surgery and Orthopedic Research Institute, Stem Cell and Tissue Engineering Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China.; Tianfu Jincheng Laboratory, Chengdu, Sichuan, PR China., Song YT; Department of Orthopedic Surgery and Orthopedic Research Institute, Stem Cell and Tissue Engineering Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China.; Tianfu Jincheng Laboratory, Chengdu, Sichuan, PR China., Shen ZX; Department of Orthopedic Surgery and Orthopedic Research Institute, Stem Cell and Tissue Engineering Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China.; Tianfu Jincheng Laboratory, Chengdu, Sichuan, PR China., Gao YY; Department of Otolaryngology-Head & Neck Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China., Dong YJ; Department of Otolaryngology-Head & Neck Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China., Tang LQ; Research Core Facility of West China Hospital, Sichuan University, Chengdu, Sichuan, PR China., Liu J; Department of Otolaryngology-Head & Neck Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China., Hu JJ; Department of Otolaryngology-Head & Neck Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China. hujuanjuan@scu.edu.cn.; Department of Orthopedic Surgery and Orthopedic Research Institute, Stem Cell and Tissue Engineering Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China. hujuanjuan@scu.edu.cn., Yang H; Department of Otolaryngology-Head & Neck Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China. yh8806@wchscu.cn., Xie HQ; Department of Orthopedic Surgery and Orthopedic Research Institute, Stem Cell and Tissue Engineering Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China. xiehuiqi@scu.edu.cn.; Tianfu Jincheng Laboratory, Chengdu, Sichuan, PR China. xiehuiqi@scu.edu.cn.
Source: Nature communications [Nat Commun] 2026 Jun 17. Date of Electronic Publication: 2026 Jun 17.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Redox-regulated in situ-forming hydrogel informed by single-cell transcriptomics for functional restoration of injured vocal folds.
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  Data: <searchLink fieldCode="AU" term="%22Xiong+M%22">Xiong M</searchLink>; Department of Otolaryngology-Head & Neck Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China.; Department of Orthopedic Surgery and Orthopedic Research Institute, Stem Cell and Tissue Engineering Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China.<br /><searchLink fieldCode="AU" term="%22Zou+CY%22">Zou CY</searchLink>; Department of Orthopedic Surgery and Orthopedic Research Institute, Stem Cell and Tissue Engineering Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China.; Tianfu Jincheng Laboratory, Chengdu, Sichuan, PR China.<br /><searchLink fieldCode="AU" term="%22Zhao+L%22">Zhao L</searchLink>; Department of Hematology and Institute of Hematology, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China.<br /><searchLink fieldCode="AU" term="%22Jiang+YL%22">Jiang YL</searchLink>; Department of Orthopedic Surgery and Orthopedic Research Institute, Stem Cell and Tissue Engineering Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China.; Tianfu Jincheng Laboratory, Chengdu, Sichuan, PR China.<br /><searchLink fieldCode="AU" term="%22Li+QJ%22">Li QJ</searchLink>; Department of Orthopedic Surgery and Orthopedic Research Institute, Stem Cell and Tissue Engineering Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China.; Tianfu Jincheng Laboratory, Chengdu, Sichuan, PR China.<br /><searchLink fieldCode="AU" term="%22Fan+MH%22">Fan MH</searchLink>; Department of Orthopedic Surgery and Orthopedic Research Institute, Stem Cell and Tissue Engineering Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China.; Tianfu Jincheng Laboratory, Chengdu, Sichuan, PR China.<br /><searchLink fieldCode="AU" term="%22Song+YT%22">Song YT</searchLink>; Department of Orthopedic Surgery and Orthopedic Research Institute, Stem Cell and Tissue Engineering Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China.; Tianfu Jincheng Laboratory, Chengdu, Sichuan, PR China.<br /><searchLink fieldCode="AU" term="%22Shen+ZX%22">Shen ZX</searchLink>; Department of Orthopedic Surgery and Orthopedic Research Institute, Stem Cell and Tissue Engineering Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China.; Tianfu Jincheng Laboratory, Chengdu, Sichuan, PR China.<br /><searchLink fieldCode="AU" term="%22Gao+YY%22">Gao YY</searchLink>; Department of Otolaryngology-Head & Neck Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China.<br /><searchLink fieldCode="AU" term="%22Dong+YJ%22">Dong YJ</searchLink>; Department of Otolaryngology-Head & Neck Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China.<br /><searchLink fieldCode="AU" term="%22Tang+LQ%22">Tang LQ</searchLink>; Research Core Facility of West China Hospital, Sichuan University, Chengdu, Sichuan, PR China.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; Department of Otolaryngology-Head & Neck Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China.<br /><searchLink fieldCode="AU" term="%22Hu+JJ%22">Hu JJ</searchLink>; Department of Otolaryngology-Head & Neck Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China. hujuanjuan@scu.edu.cn.; Department of Orthopedic Surgery and Orthopedic Research Institute, Stem Cell and Tissue Engineering Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China. hujuanjuan@scu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Yang+H%22">Yang H</searchLink>; Department of Otolaryngology-Head & Neck Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China. yh8806@wchscu.cn.<br /><searchLink fieldCode="AU" term="%22Xie+HQ%22">Xie HQ</searchLink>; Department of Orthopedic Surgery and Orthopedic Research Institute, Stem Cell and Tissue Engineering Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China. xiehuiqi@scu.edu.cn.; Tianfu Jincheng Laboratory, Chengdu, Sichuan, PR China. xiehuiqi@scu.edu.cn.
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        Value: 10.1038/s41467-026-74477-z
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