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Argonaute 2 drives resistance to immune checkpoint inhibitors in immunorefractory non-small cell lung cancer.

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Title: Argonaute 2 drives resistance to immune checkpoint inhibitors in immunorefractory non-small cell lung cancer.
Authors: Anobile DP; Innate Immunity in Physiology and Cancer Team, Institut Curie, PSL Research University, INSERM U932, Paris, France.; Translational Immunotherapy Team, Institut Curie, PSL Research University, INSERM U932, Paris, France., Barbar L; Innate Immunity in Physiology and Cancer Team, Institut Curie, PSL Research University, INSERM U932, Paris, France., Maucotel E; Innate Immunity in Physiology and Cancer Team, Institut Curie, PSL Research University, INSERM U932, Paris, France., Cornec A; Innate Immunity in Physiology and Cancer Team, Institut Curie, PSL Research University, INSERM U932, Paris, France., Manriquez V; Translational Immunotherapy Team, Institut Curie, PSL Research University, INSERM U932, Paris, France.; Department of Translational Research, PSL University, Institut Curie Research Center, Paris, France., Richer W; Translational Immunotherapy Team, Institut Curie, PSL Research University, INSERM U932, Paris, France.; Department of Translational Research, PSL University, Institut Curie Research Center, Paris, France., Denizeau J; Translational Immunotherapy Team, Institut Curie, PSL Research University, INSERM U932, Paris, France.; Department of Translational Research, PSL University, Institut Curie Research Center, Paris, France., Sedlik C; Translational Immunotherapy Team, Institut Curie, PSL Research University, INSERM U932, Paris, France.; Department of Translational Research, PSL University, Institut Curie Research Center, Paris, France., Bories C; Innate Immunity in Physiology and Cancer Team, Institut Curie, PSL Research University, INSERM U932, Paris, France., Couderc E; Innate Immunity in Physiology and Cancer Team, Institut Curie, PSL Research University, INSERM U932, Paris, France., Leclere R; Department of Diagnostic and Theragnostic Medicine, BioHub, Pathex, Institut Curie Research Center, Paris, France., Sobas J; Department of Diagnostic and Theragnostic Medicine, BioHub, Pathex, Institut Curie Research Center, Paris, France., Papillon E; Tolerance and Anti-tumour Immunity Team, Institut Curie, PSL Research University, INSERM U932, Paris, France., Mena Osuna R; Translational Immunotherapy Team, Institut Curie, PSL Research University, INSERM U932, Paris, France.; Department of Translational Research, PSL University, Institut Curie Research Center, Paris, France., Tosello-Boari J; Translational Immunotherapy Team, Institut Curie, PSL Research University, INSERM U932, Paris, France.; Department of Translational Research, PSL University, Institut Curie Research Center, Paris, France., Burbage M; Tolerance and Anti-tumour Immunity Team, Institut Curie, PSL Research University, INSERM U932, Paris, France., Piaggio E; Translational Immunotherapy Team, Institut Curie, PSL Research University, INSERM U932, Paris, France.; Department of Translational Research, PSL University, Institut Curie Research Center, Paris, France., Poirier EZ; Innate Immunity in Physiology and Cancer Team, Institut Curie, PSL Research University, INSERM U932, Paris, France.
Source: PLoS biology [PLoS Biol] 2026 Jun 18; Vol. 24 (6), pp. e3003860. Date of Electronic Publication: 2026 Jun 18 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE
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  Data: Argonaute 2 drives resistance to immune checkpoint inhibitors in immunorefractory non-small cell lung cancer.
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  Data: <searchLink fieldCode="AU" term="%22Anobile+DP%22">Anobile DP</searchLink>; Innate Immunity in Physiology and Cancer Team, Institut Curie, PSL Research University, INSERM U932, Paris, France.; Translational Immunotherapy Team, Institut Curie, PSL Research University, INSERM U932, Paris, France.<br /><searchLink fieldCode="AU" term="%22Barbar+L%22">Barbar L</searchLink>; Innate Immunity in Physiology and Cancer Team, Institut Curie, PSL Research University, INSERM U932, Paris, France.<br /><searchLink fieldCode="AU" term="%22Maucotel+E%22">Maucotel E</searchLink>; Innate Immunity in Physiology and Cancer Team, Institut Curie, PSL Research University, INSERM U932, Paris, France.<br /><searchLink fieldCode="AU" term="%22Cornec+A%22">Cornec A</searchLink>; Innate Immunity in Physiology and Cancer Team, Institut Curie, PSL Research University, INSERM U932, Paris, France.<br /><searchLink fieldCode="AU" term="%22Manriquez+V%22">Manriquez V</searchLink>; Translational Immunotherapy Team, Institut Curie, PSL Research University, INSERM U932, Paris, France.; Department of Translational Research, PSL University, Institut Curie Research Center, Paris, France.<br /><searchLink fieldCode="AU" term="%22Richer+W%22">Richer W</searchLink>; Translational Immunotherapy Team, Institut Curie, PSL Research University, INSERM U932, Paris, France.; Department of Translational Research, PSL University, Institut Curie Research Center, Paris, France.<br /><searchLink fieldCode="AU" term="%22Denizeau+J%22">Denizeau J</searchLink>; Translational Immunotherapy Team, Institut Curie, PSL Research University, INSERM U932, Paris, France.; Department of Translational Research, PSL University, Institut Curie Research Center, Paris, France.<br /><searchLink fieldCode="AU" term="%22Sedlik+C%22">Sedlik C</searchLink>; Translational Immunotherapy Team, Institut Curie, PSL Research University, INSERM U932, Paris, France.; Department of Translational Research, PSL University, Institut Curie Research Center, Paris, France.<br /><searchLink fieldCode="AU" term="%22Bories+C%22">Bories C</searchLink>; Innate Immunity in Physiology and Cancer Team, Institut Curie, PSL Research University, INSERM U932, Paris, France.<br /><searchLink fieldCode="AU" term="%22Couderc+E%22">Couderc E</searchLink>; Innate Immunity in Physiology and Cancer Team, Institut Curie, PSL Research University, INSERM U932, Paris, France.<br /><searchLink fieldCode="AU" term="%22Leclere+R%22">Leclere R</searchLink>; Department of Diagnostic and Theragnostic Medicine, BioHub, Pathex, Institut Curie Research Center, Paris, France.<br /><searchLink fieldCode="AU" term="%22Sobas+J%22">Sobas J</searchLink>; Department of Diagnostic and Theragnostic Medicine, BioHub, Pathex, Institut Curie Research Center, Paris, France.<br /><searchLink fieldCode="AU" term="%22Papillon+E%22">Papillon E</searchLink>; Tolerance and Anti-tumour Immunity Team, Institut Curie, PSL Research University, INSERM U932, Paris, France.<br /><searchLink fieldCode="AU" term="%22Mena+Osuna+R%22">Mena Osuna R</searchLink>; Translational Immunotherapy Team, Institut Curie, PSL Research University, INSERM U932, Paris, France.; Department of Translational Research, PSL University, Institut Curie Research Center, Paris, France.<br /><searchLink fieldCode="AU" term="%22Tosello-Boari+J%22">Tosello-Boari J</searchLink>; Translational Immunotherapy Team, Institut Curie, PSL Research University, INSERM U932, Paris, France.; Department of Translational Research, PSL University, Institut Curie Research Center, Paris, France.<br /><searchLink fieldCode="AU" term="%22Burbage+M%22">Burbage M</searchLink>; Tolerance and Anti-tumour Immunity Team, Institut Curie, PSL Research University, INSERM U932, Paris, France.<br /><searchLink fieldCode="AU" term="%22Piaggio+E%22">Piaggio E</searchLink>; Translational Immunotherapy Team, Institut Curie, PSL Research University, INSERM U932, Paris, France.; Department of Translational Research, PSL University, Institut Curie Research Center, Paris, France.<br /><searchLink fieldCode="AU" term="%22Poirier+EZ%22">Poirier EZ</searchLink>; Innate Immunity in Physiology and Cancer Team, Institut Curie, PSL Research University, INSERM U932, Paris, France.
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  Data: <searchLink fieldCode="JN" term="%22101183755%22">PLoS biology</searchLink> [PLoS Biol] 2026 Jun 18; Vol. 24 (6), pp. e3003860. <i>Date of Electronic Publication: </i>2026 Jun 18 (<i>Print Publication: </i>2026).
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