The Changing Landscape of Maintenance Therapy in Newly Diagnosed Multiple Myeloma: A Systematic Review With Network Meta-Analysis of the European Myeloma Network (EMN).

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Title: The Changing Landscape of Maintenance Therapy in Newly Diagnosed Multiple Myeloma: A Systematic Review With Network Meta-Analysis of the European Myeloma Network (EMN).
Authors: Ludwig H; Wilhelminen Cancer Research Institute, First Department of Medicine, Center for Oncology, Hematology and Palliative Care, Clinic Ottakring, Vienna, Austria., Terpos E; Department of Clinical Therapeutics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece., Gay F; Myeloma Unit, Division of Hematology, University of Torino, Azienda Ospedaliero-Universitaria Città Della Salute e Della Scienza di Torino, Torino, Italy., van de Donk NWCJ; Department of Hematology, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam, the Netherlands., Bernhard S; Wilhelminen Cancer Research Institute, First Department of Medicine, Center for Oncology, Hematology and Palliative Care, Clinic Ottakring, Vienna, Austria., Engelhardt M; Department of Hematology and Oncology, Interdisciplinary Cancer Center and Comprehensive Cancer Center Freiburg, University of Freiburg, Faculty of Freiburg, Freiburg, Germany., Cook G; NIHR Leeds BRC and CRUK Clinical Trials Unit, Leeds Institute of Clinical Trial Research, Leeds, UK., Schjesvold F; Oslo Myeloma Center, Department of Hematology, Oslo University Hospital, Oslo, Norway., Einsele H; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany., Jackson G; Department of Haematology, Newcastle University, Newcastle, UK., Pawlyn C; The Institute of Cancer Research, London, UK.; The Royal Marsden Hospital NHS Foundation Trust, London, UK., Mateos MV; Department of Hematology, University Hospital of Salamanca/IBSAL, Salamanca, Spain., Zweegman S; Department of Hematology, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam, the Netherlands., Schreder M; First Department of Medicine, Center for Oncology, Hematology, and Palliative Care, Clinic Ottakring, Vienna, Austria., Beksaç M; Department of Hematology, Istinye University, Ankara Liv Hospital, Ankara, Turkey., Driessen C; Department of Oncology/Hematology, Kantonsspital, St. Gallen, Switzerland., Ocio EM; Servicio de Hematología y Hemoterapia, Hospital Universitario Marqués de Valdecilla (IDIVAL), Universidad de Cantabria, Santander, Spain., Popat R; NIHR/UCLH Clinical Research Facility, University College London Hospitals NHS Foundation Trust, London, UK., Rasche L; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany., Touzeau C; Service D'hématologie Clinique, Centre Hospitalier Universitaire Hôtel-Dieu, Nantes, France., Musto P; Department of Precision and Regenerative Medicine and Ionian Area, 'Aldo Moro' University School of Medicine, Bari, Italy.; Unit of Hematology and Stem Cell Transplantation, AOU Consorziale Policlinico, Bari, Italy., Broijl A; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands., Dimopoulos M; Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece.; Department of Medicine, Korea University, Seoul, Republic of Korea., Hajek R; FN Ostrava, Ostrava, Czech Republic., Boccadoro M; European Myeloma Network (EMN), Torino, Italy., Sonneveld P; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Source: American journal of hematology [Am J Hematol] 2026 Jun 18. Date of Electronic Publication: 2026 Jun 18.
Publication Type: Journal Article; Review
Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 7610369 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-8652 (Electronic) Linking ISSN: 03618609 NLM ISO Abbreviation: Am J Hematol Subsets: MEDLINE
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  Data: The Changing Landscape of Maintenance Therapy in Newly Diagnosed Multiple Myeloma: A Systematic Review With Network Meta-Analysis of the European Myeloma Network (EMN).
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  Data: <searchLink fieldCode="AU" term="%22Ludwig+H%22">Ludwig H</searchLink>; Wilhelminen Cancer Research Institute, First Department of Medicine, Center for Oncology, Hematology and Palliative Care, Clinic Ottakring, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Terpos+E%22">Terpos E</searchLink>; Department of Clinical Therapeutics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Gay+F%22">Gay F</searchLink>; Myeloma Unit, Division of Hematology, University of Torino, Azienda Ospedaliero-Universitaria Città Della Salute e Della Scienza di Torino, Torino, Italy.<br /><searchLink fieldCode="AU" term="%22van+de+Donk+NWCJ%22">van de Donk NWCJ</searchLink>; Department of Hematology, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Bernhard+S%22">Bernhard S</searchLink>; Wilhelminen Cancer Research Institute, First Department of Medicine, Center for Oncology, Hematology and Palliative Care, Clinic Ottakring, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Engelhardt+M%22">Engelhardt M</searchLink>; Department of Hematology and Oncology, Interdisciplinary Cancer Center and Comprehensive Cancer Center Freiburg, University of Freiburg, Faculty of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Cook+G%22">Cook G</searchLink>; NIHR Leeds BRC and CRUK Clinical Trials Unit, Leeds Institute of Clinical Trial Research, Leeds, UK.<br /><searchLink fieldCode="AU" term="%22Schjesvold+F%22">Schjesvold F</searchLink>; Oslo Myeloma Center, Department of Hematology, Oslo University Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Einsele+H%22">Einsele H</searchLink>; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Jackson+G%22">Jackson G</searchLink>; Department of Haematology, Newcastle University, Newcastle, UK.<br /><searchLink fieldCode="AU" term="%22Pawlyn+C%22">Pawlyn C</searchLink>; The Institute of Cancer Research, London, UK.; The Royal Marsden Hospital NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Mateos+MV%22">Mateos MV</searchLink>; Department of Hematology, University Hospital of Salamanca/IBSAL, Salamanca, Spain.<br /><searchLink fieldCode="AU" term="%22Zweegman+S%22">Zweegman S</searchLink>; Department of Hematology, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Schreder+M%22">Schreder M</searchLink>; First Department of Medicine, Center for Oncology, Hematology, and Palliative Care, Clinic Ottakring, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Beksaç+M%22">Beksaç M</searchLink>; Department of Hematology, Istinye University, Ankara Liv Hospital, Ankara, Turkey.<br /><searchLink fieldCode="AU" term="%22Driessen+C%22">Driessen C</searchLink>; Department of Oncology/Hematology, Kantonsspital, St. Gallen, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ocio+EM%22">Ocio EM</searchLink>; Servicio de Hematología y Hemoterapia, Hospital Universitario Marqués de Valdecilla (IDIVAL), Universidad de Cantabria, Santander, Spain.<br /><searchLink fieldCode="AU" term="%22Popat+R%22">Popat R</searchLink>; NIHR/UCLH Clinical Research Facility, University College London Hospitals NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Rasche+L%22">Rasche L</searchLink>; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Touzeau+C%22">Touzeau C</searchLink>; Service D'hématologie Clinique, Centre Hospitalier Universitaire Hôtel-Dieu, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Musto+P%22">Musto P</searchLink>; Department of Precision and Regenerative Medicine and Ionian Area, 'Aldo Moro' University School of Medicine, Bari, Italy.; Unit of Hematology and Stem Cell Transplantation, AOU Consorziale Policlinico, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Broijl+A%22">Broijl A</searchLink>; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Dimopoulos+M%22">Dimopoulos M</searchLink>; Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece.; Department of Medicine, Korea University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Hajek+R%22">Hajek R</searchLink>; FN Ostrava, Ostrava, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Boccadoro+M%22">Boccadoro M</searchLink>; European Myeloma Network (EMN), Torino, Italy.<br /><searchLink fieldCode="AU" term="%22Sonneveld+P%22">Sonneveld P</searchLink>; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
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