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Abdominal fat distribution phenotypes and metabolic risk in premenopausal Asian women: insights beyond general adiposity measures.

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Title: Abdominal fat distribution phenotypes and metabolic risk in premenopausal Asian women: insights beyond general adiposity measures.
Authors: Kway YM; Institute for Human Development and Potential, Agency for Science, Technology and Research, Singapore, Singapore. yeshekway@u.nus.edu.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. yeshekway@u.nus.edu., Michael N; Institute for Human Development and Potential, Agency for Science, Technology and Research, Singapore, Singapore., Kothandaraman N; Institute for Human Development and Potential, Agency for Science, Technology and Research, Singapore, Singapore., Yaligar J; Institute for Human Development and Potential, Agency for Science, Technology and Research, Singapore, Singapore., Tint MT; Institute for Human Development and Potential, Agency for Science, Technology and Research, Singapore, Singapore., Tan KH; Graduate Medical School, Duke-National University of Singapore, Singapore, Singapore.; Department of Maternal Fetal Medicine, KK Women's and Children's Hospital, Singapore, Singapore., Godfrey KM; MRC Lifecourse Epidemiology Centre & NIHR Southampton Biomedical Research Centre, University of Southampton & University Hospital Southampton NHS Foundation Trust, Southampton, UK., Gluckman PD; Institute for Human Development and Potential, Agency for Science, Technology and Research, Singapore, Singapore.; Centre for Human Evolution, Adaptation and Disease, Liggins Institute, University of Auckland, Auckland, New Zealand., Chong YS; Institute for Human Development and Potential, Agency for Science, Technology and Research, Singapore, Singapore.; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Leow MK; Institute for Human Development and Potential, Agency for Science, Technology and Research, Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University (NTU), Singapore, Singapore.; Human Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Department of Endocrinology, Division of Medicine, Tan Tock Seng Hospital (TTSH), Singapore, Singapore., Chan JKY; Department of Reproductive Medicine, KK Women's and Children's Hospital, Singapore, Singapore.; Experimental Fetal Medicine Group, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Chan SY; Institute for Human Development and Potential, Agency for Science, Technology and Research, Singapore, Singapore.; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Fortier MV; Institute for Human Development and Potential, Agency for Science, Technology and Research, Singapore, Singapore.; Graduate Medical School, Duke-National University of Singapore, Singapore, Singapore.; Department of Diagnostic and Interventional Imaging, KK Women's and Children's Hospital, Singapore, Singapore., Eriksson JG; Institute for Human Development and Potential, Agency for Science, Technology and Research, Singapore, Singapore.; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Human Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Folkhälsan Research Center, Helsinki, Finland., Huang J; Institute for Human Development and Potential, Agency for Science, Technology and Research, Singapore, Singapore.; Graduate Medical School, Duke-National University of Singapore, Singapore, Singapore., Lee YS; Institute for Human Development and Potential, Agency for Science, Technology and Research, Singapore, Singapore.; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Division of Paediatric Endocrinology, Department of Paediatrics, Khoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore, Singapore., Feng M; Institute of Data Science, National University of Singapore, Singapore, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, National University Health System, Singapore, Singapore., Velan SS; Institute for Human Development and Potential, Agency for Science, Technology and Research, Singapore, Singapore.; Institute for Applied Life Sciences, Human Magnetic Resonance Center, University of Massachusetts Amherst, Amherst, USA., Sadananthan SA; Institute for Human Development and Potential, Agency for Science, Technology and Research, Singapore, Singapore.; Human Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Source: Scientific reports [Sci Rep] 2026 Jun 18. Date of Electronic Publication: 2026 Jun 18.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Kway+YM%22">Kway YM</searchLink>; Institute for Human Development and Potential, Agency for Science, Technology and Research, Singapore, Singapore. yeshekway@u.nus.edu.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. yeshekway@u.nus.edu.<br /><searchLink fieldCode="AU" term="%22Michael+N%22">Michael N</searchLink>; Institute for Human Development and Potential, Agency for Science, Technology and Research, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Kothandaraman+N%22">Kothandaraman N</searchLink>; Institute for Human Development and Potential, Agency for Science, Technology and Research, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Yaligar+J%22">Yaligar J</searchLink>; Institute for Human Development and Potential, Agency for Science, Technology and Research, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Tint+MT%22">Tint MT</searchLink>; Institute for Human Development and Potential, Agency for Science, Technology and Research, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Tan+KH%22">Tan KH</searchLink>; Graduate Medical School, Duke-National University of Singapore, Singapore, Singapore.; Department of Maternal Fetal Medicine, KK Women's and Children's Hospital, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Godfrey+KM%22">Godfrey KM</searchLink>; MRC Lifecourse Epidemiology Centre & NIHR Southampton Biomedical Research Centre, University of Southampton & University Hospital Southampton NHS Foundation Trust, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Gluckman+PD%22">Gluckman PD</searchLink>; Institute for Human Development and Potential, Agency for Science, Technology and Research, Singapore, Singapore.; Centre for Human Evolution, Adaptation and Disease, Liggins Institute, University of Auckland, Auckland, New Zealand.<br /><searchLink fieldCode="AU" term="%22Chong+YS%22">Chong YS</searchLink>; Institute for Human Development and Potential, Agency for Science, Technology and Research, Singapore, Singapore.; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Leow+MK%22">Leow MK</searchLink>; Institute for Human Development and Potential, Agency for Science, Technology and Research, Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University (NTU), Singapore, Singapore.; Human Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Department of Endocrinology, Division of Medicine, Tan Tock Seng Hospital (TTSH), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Chan+JKY%22">Chan JKY</searchLink>; Department of Reproductive Medicine, KK Women's and Children's Hospital, Singapore, Singapore.; Experimental Fetal Medicine Group, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Chan+SY%22">Chan SY</searchLink>; Institute for Human Development and Potential, Agency for Science, Technology and Research, Singapore, Singapore.; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Fortier+MV%22">Fortier MV</searchLink>; Institute for Human Development and Potential, Agency for Science, Technology and Research, Singapore, Singapore.; Graduate Medical School, Duke-National University of Singapore, Singapore, Singapore.; Department of Diagnostic and Interventional Imaging, KK Women's and Children's Hospital, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Eriksson+JG%22">Eriksson JG</searchLink>; Institute for Human Development and Potential, Agency for Science, Technology and Research, Singapore, Singapore.; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Human Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Folkhälsan Research Center, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Huang+J%22">Huang J</searchLink>; Institute for Human Development and Potential, Agency for Science, Technology and Research, Singapore, Singapore.; Graduate Medical School, Duke-National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Lee+YS%22">Lee YS</searchLink>; Institute for Human Development and Potential, Agency for Science, Technology and Research, Singapore, Singapore.; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Division of Paediatric Endocrinology, Department of Paediatrics, Khoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Feng+M%22">Feng M</searchLink>; Institute of Data Science, National University of Singapore, Singapore, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, National University Health System, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Velan+SS%22">Velan SS</searchLink>; Institute for Human Development and Potential, Agency for Science, Technology and Research, Singapore, Singapore.; Institute for Applied Life Sciences, Human Magnetic Resonance Center, University of Massachusetts Amherst, Amherst, USA.<br /><searchLink fieldCode="AU" term="%22Sadananthan+SA%22">Sadananthan SA</searchLink>; Institute for Human Development and Potential, Agency for Science, Technology and Research, Singapore, Singapore.; Human Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
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