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Efficacy and safety of adjuvant tirofiban versus intravenous thrombolysis alone in acute ischemic stroke: an updated meta-analysis of randomized controlled trials.

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Title: Efficacy and safety of adjuvant tirofiban versus intravenous thrombolysis alone in acute ischemic stroke: an updated meta-analysis of randomized controlled trials.
Authors: Leite M; School of Medicine, Santa Marcelina College, Rua Cachoeira Utupanema, 40, São Paulo, Brazil. marianna.leite@usp.br.; University of São Paulo, São Paulo, Brazil. marianna.leite@usp.br., Ribeiro Gonçalves O; Federal University of Piauí, Teresina, Piauí, Brazil., de Almeida Monteiro G; School of Medicine, Federal University of Ceará, Sobral, Brazil., Marinheiro G; School of Medicine, Federal University of Ceará, Sobral, Brazil., Mutarelli A; School of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil., Pereira da Silva AM; Department of Biostatistics and Clinical Epidemiology, Memory Hub, Cognitive and Neurodegenerative Disorders Research Group, São Paulo, Brazil., Andrade Fernandes JV; Medical Sciences Center, Federal University of Paraíba, João Pessoa, Brazil., Pensenstadler K; Helios Klinikum Erfurt, Erfurt, Germany., Singh J; School of Medicine, Creighton University, Omaha (NE), USA., Lee WJ; SUNY Downstate Medical Center, Brooklyn, USA., Pipek L; University of São Paulo, São Paulo, Brazil., Mota Telles JP; University of São Paulo, São Paulo, Brazil.
Source: Journal of thrombosis and thrombolysis [J Thromb Thrombolysis] 2026 Jun 18. Date of Electronic Publication: 2026 Jun 18.
Publication Type: Journal Article; Review
Journal Info: Publisher: Kluwer Academic Publishers Country of Publication: Netherlands NLM ID: 9502018 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-742X (Electronic) Linking ISSN: 09295305 NLM ISO Abbreviation: J Thromb Thrombolysis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Efficacy and safety of adjuvant tirofiban versus intravenous thrombolysis alone in acute ischemic stroke: an updated meta-analysis of randomized controlled trials.
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  Data: <searchLink fieldCode="AU" term="%22Leite+M%22">Leite M</searchLink>; School of Medicine, Santa Marcelina College, Rua Cachoeira Utupanema, 40, São Paulo, Brazil. marianna.leite@usp.br.; University of São Paulo, São Paulo, Brazil. marianna.leite@usp.br.<br /><searchLink fieldCode="AU" term="%22Ribeiro+Gonçalves+O%22">Ribeiro Gonçalves O</searchLink>; Federal University of Piauí, Teresina, Piauí, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Almeida+Monteiro+G%22">de Almeida Monteiro G</searchLink>; School of Medicine, Federal University of Ceará, Sobral, Brazil.<br /><searchLink fieldCode="AU" term="%22Marinheiro+G%22">Marinheiro G</searchLink>; School of Medicine, Federal University of Ceará, Sobral, Brazil.<br /><searchLink fieldCode="AU" term="%22Mutarelli+A%22">Mutarelli A</searchLink>; School of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil.<br /><searchLink fieldCode="AU" term="%22Pereira+da+Silva+AM%22">Pereira da Silva AM</searchLink>; Department of Biostatistics and Clinical Epidemiology, Memory Hub, Cognitive and Neurodegenerative Disorders Research Group, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Andrade+Fernandes+JV%22">Andrade Fernandes JV</searchLink>; Medical Sciences Center, Federal University of Paraíba, João Pessoa, Brazil.<br /><searchLink fieldCode="AU" term="%22Pensenstadler+K%22">Pensenstadler K</searchLink>; Helios Klinikum Erfurt, Erfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Singh+J%22">Singh J</searchLink>; School of Medicine, Creighton University, Omaha (NE), USA.<br /><searchLink fieldCode="AU" term="%22Lee+WJ%22">Lee WJ</searchLink>; SUNY Downstate Medical Center, Brooklyn, USA.<br /><searchLink fieldCode="AU" term="%22Pipek+L%22">Pipek L</searchLink>; University of São Paulo, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Mota+Telles+JP%22">Mota Telles JP</searchLink>; University of São Paulo, São Paulo, Brazil.
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  Data: <searchLink fieldCode="JN" term="%229502018%22">Journal of thrombosis and thrombolysis</searchLink> [J Thromb Thrombolysis] 2026 Jun 18. <i>Date of Electronic Publication: </i>2026 Jun 18.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Kluwer+Academic+Publishers%22">Kluwer Academic Publishers </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>9502018 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-742X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209295305%22">09295305 </searchLink><i>NLM ISO Abbreviation: </i>J Thromb Thrombolysis <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s11239-026-03335-y
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        Text: English
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              Text: 2026 Jun 18
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