IGNITE: a phase III study of tirabrutinib versus rituximab and temozolomide combination therapy in relapsed/refractory primary central nervous system lymphoma.

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Title: IGNITE: a phase III study of tirabrutinib versus rituximab and temozolomide combination therapy in relapsed/refractory primary central nervous system lymphoma.
Authors: Nayak L; Neuro-oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Grommes C; Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Psoinos C; Clinical Development, Deciphera Pharmaceuticals LLC, Waltham, MA, USA., Reu FJ; Clinical Development, Deciphera Pharmaceuticals LLC, Waltham, MA, USA., Takazawa A; Clinical Development, ONO Pharmaceutical Co, Ltd, Osaka, Japan., Uttarwar M; Clinical Development, Deciphera Pharmaceuticals LLC, Waltham, MA, USA., Xia B; Clinical Development, Deciphera Pharmaceuticals LLC, Waltham, MA, USA., Carvajal LA; Clinical Development, Deciphera Pharmaceuticals LLC, Waltham, MA, USA., Kim S; Clinical Development, Deciphera Pharmaceuticals LLC, Waltham, MA, USA., Sherman ML; Clinical Development, Deciphera Pharmaceuticals LLC, Waltham, MA, USA., Batchelor TT; Neurology, Brigham and Women's Hospital, Boston, MA, USA.
Source: Future oncology (London, England) [Future Oncol] 2026 Jun 19, pp. 1-7. Date of Electronic Publication: 2026 Jun 19.
Publication Type: Journal Article
Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101256629 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-8301 (Electronic) Linking ISSN: 14796694 NLM ISO Abbreviation: Future Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: IGNITE: a phase III study of tirabrutinib versus rituximab and temozolomide combination therapy in relapsed/refractory primary central nervous system lymphoma.
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  Data: <searchLink fieldCode="AU" term="%22Nayak+L%22">Nayak L</searchLink>; Neuro-oncology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Grommes+C%22">Grommes C</searchLink>; Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Psoinos+C%22">Psoinos C</searchLink>; Clinical Development, Deciphera Pharmaceuticals LLC, Waltham, MA, USA.<br /><searchLink fieldCode="AU" term="%22Reu+FJ%22">Reu FJ</searchLink>; Clinical Development, Deciphera Pharmaceuticals LLC, Waltham, MA, USA.<br /><searchLink fieldCode="AU" term="%22Takazawa+A%22">Takazawa A</searchLink>; Clinical Development, ONO Pharmaceutical Co, Ltd, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Uttarwar+M%22">Uttarwar M</searchLink>; Clinical Development, Deciphera Pharmaceuticals LLC, Waltham, MA, USA.<br /><searchLink fieldCode="AU" term="%22Xia+B%22">Xia B</searchLink>; Clinical Development, Deciphera Pharmaceuticals LLC, Waltham, MA, USA.<br /><searchLink fieldCode="AU" term="%22Carvajal+LA%22">Carvajal LA</searchLink>; Clinical Development, Deciphera Pharmaceuticals LLC, Waltham, MA, USA.<br /><searchLink fieldCode="AU" term="%22Kim+S%22">Kim S</searchLink>; Clinical Development, Deciphera Pharmaceuticals LLC, Waltham, MA, USA.<br /><searchLink fieldCode="AU" term="%22Sherman+ML%22">Sherman ML</searchLink>; Clinical Development, Deciphera Pharmaceuticals LLC, Waltham, MA, USA.<br /><searchLink fieldCode="AU" term="%22Batchelor+TT%22">Batchelor TT</searchLink>; Neurology, Brigham and Women's Hospital, Boston, MA, USA.
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  Data: <searchLink fieldCode="JN" term="%22101256629%22">Future oncology (London, England)</searchLink> [Future Oncol] 2026 Jun 19, pp. 1-7. <i>Date of Electronic Publication: </i>2026 Jun 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Taylor+%26+Francis%22">Taylor & Francis </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101256629 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1744-8301 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214796694%22">14796694 </searchLink><i>NLM ISO Abbreviation: </i>Future Oncol <i>Subsets: </i>MEDLINE
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        Value: 10.1080/14796694.2026.2683574
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              Text: 2026 Jun 19
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