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Tumor-associated epilepsy at diagnosis in glioblastoma patients reveals an inflammatory molecular signature and is associated with better overall survival.

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Title: Tumor-associated epilepsy at diagnosis in glioblastoma patients reveals an inflammatory molecular signature and is associated with better overall survival.
Authors: Dimova L; Department of Neurosurgery, RWTH Aachen University, Germany., Stritzelberger J; Department of Neurology, University Hospital Erlangen, Friedrich-Alexander University Erlangen Nürnberg, Erlangen, Germany., Dimov D; Department of Neurosurgery, University Hospital OWL, Campus Bielefeld-Bethel, Bielefeld, Germany., Ort J; Department of Neurosurgery, RWTH Aachen University, Germany., Hamou HA; Department of Neurosurgery, RWTH Aachen University, Germany., Clusmann H; Department of Neurosurgery, RWTH Aachen University, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Germany., Schnell O; Department of Neurosurgery, University Hospital Erlangen, Friedrich-Alexander University Erlangen Nürnberg, Erlangen, Germany., Hamer H; Department of Neurology, University Hospital Erlangen, Friedrich-Alexander University Erlangen Nürnberg, Erlangen, Germany., Putz F; Department of Radiooncology, University Hospital Erlangen, Friedrich-Alexander University Erlangen Nürnberg, Erlangen, Germany., Corradini S; Department of Radiooncology, University Hospital Erlangen, Friedrich-Alexander University Erlangen Nürnberg, Erlangen, Germany., Singer L; Department of Neuroradiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Dörfler A; Department of Neuroradiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Ricklefs F; Department of Neurosurgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Drexler R; Department of Neurosurgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of Neurology and Neurology Sciences, Stanford University, Stanford, California, USA., Simon M; Department of Neurosurgery, University Hospital OWL, Campus Bielefeld-Bethel, Bielefeld, Germany., Heiland DH; Department of Neurosurgery, University Hospital Erlangen, Friedrich-Alexander University Erlangen Nürnberg, Erlangen, Germany.; Department of Translational Neurosurgery, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.; Department of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Delev D; Department of Neurosurgery, RWTH Aachen University, Germany.; Department of Neurosurgery, University Hospital Erlangen, Friedrich-Alexander University Erlangen Nürnberg, Erlangen, Germany.
Source: Neuro-oncology [Neuro Oncol] 2026 Jun 19. Date of Electronic Publication: 2026 Jun 19.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 100887420 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-5866 (Electronic) Linking ISSN: 15228517 NLM ISO Abbreviation: Neuro Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Tumor-associated epilepsy at diagnosis in glioblastoma patients reveals an inflammatory molecular signature and is associated with better overall survival.
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  Data: <searchLink fieldCode="AU" term="%22Dimova+L%22">Dimova L</searchLink>; Department of Neurosurgery, RWTH Aachen University, Germany.<br /><searchLink fieldCode="AU" term="%22Stritzelberger+J%22">Stritzelberger J</searchLink>; Department of Neurology, University Hospital Erlangen, Friedrich-Alexander University Erlangen Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Dimov+D%22">Dimov D</searchLink>; Department of Neurosurgery, University Hospital OWL, Campus Bielefeld-Bethel, Bielefeld, Germany.<br /><searchLink fieldCode="AU" term="%22Ort+J%22">Ort J</searchLink>; Department of Neurosurgery, RWTH Aachen University, Germany.<br /><searchLink fieldCode="AU" term="%22Hamou+HA%22">Hamou HA</searchLink>; Department of Neurosurgery, RWTH Aachen University, Germany.<br /><searchLink fieldCode="AU" term="%22Clusmann+H%22">Clusmann H</searchLink>; Department of Neurosurgery, RWTH Aachen University, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Germany.<br /><searchLink fieldCode="AU" term="%22Schnell+O%22">Schnell O</searchLink>; Department of Neurosurgery, University Hospital Erlangen, Friedrich-Alexander University Erlangen Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Hamer+H%22">Hamer H</searchLink>; Department of Neurology, University Hospital Erlangen, Friedrich-Alexander University Erlangen Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Putz+F%22">Putz F</searchLink>; Department of Radiooncology, University Hospital Erlangen, Friedrich-Alexander University Erlangen Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Corradini+S%22">Corradini S</searchLink>; Department of Radiooncology, University Hospital Erlangen, Friedrich-Alexander University Erlangen Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Singer+L%22">Singer L</searchLink>; Department of Neuroradiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Dörfler+A%22">Dörfler A</searchLink>; Department of Neuroradiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Ricklefs+F%22">Ricklefs F</searchLink>; Department of Neurosurgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Drexler+R%22">Drexler R</searchLink>; Department of Neurosurgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of Neurology and Neurology Sciences, Stanford University, Stanford, California, USA.<br /><searchLink fieldCode="AU" term="%22Simon+M%22">Simon M</searchLink>; Department of Neurosurgery, University Hospital OWL, Campus Bielefeld-Bethel, Bielefeld, Germany.<br /><searchLink fieldCode="AU" term="%22Heiland+DH%22">Heiland DH</searchLink>; Department of Neurosurgery, University Hospital Erlangen, Friedrich-Alexander University Erlangen Nürnberg, Erlangen, Germany.; Department of Translational Neurosurgery, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.; Department of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Delev+D%22">Delev D</searchLink>; Department of Neurosurgery, RWTH Aachen University, Germany.; Department of Neurosurgery, University Hospital Erlangen, Friedrich-Alexander University Erlangen Nürnberg, Erlangen, Germany.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100887420 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1523-5866 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215228517%22">15228517 </searchLink><i>NLM ISO Abbreviation: </i>Neuro Oncol <i>Subsets: </i>MEDLINE
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              Text: 2026 Jun 19
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