Delivering effective non-invasive ventilation in amyotrophic lateral sclerosis using intensive remote support (DENIM): protocol for an embedded process evaluation in a hybrid type 3 implementation-effectiveness trial.

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Title: Delivering effective non-invasive ventilation in amyotrophic lateral sclerosis using intensive remote support (DENIM): protocol for an embedded process evaluation in a hybrid type 3 implementation-effectiveness trial.
Authors: Girling C; School of Medicine and Population Health, University of Sheffield, Sheffield, UK. c.girling@sheffield.ac.uk., Ryan G; School of Medicine and Population Health, University of Sheffield, Sheffield, UK., Bradburn M; School of Medicine and Population Health, University of Sheffield, Sheffield, UK., Caprioli T; School of Medicine and Population Health, University of Sheffield, Sheffield, UK., Dawson S; School of Medicine and Population Health, University of Sheffield, Sheffield, UK., Fisher E; School of Medicine and Population Health, University of Sheffield, Sheffield, UK., Haynes N; School of Medicine and Population Health, University of Sheffield, Sheffield, UK., Herbert E; School of Medicine and Population Health, University of Sheffield, Sheffield, UK., Hill H; School of Medicine and Population Health, University of Sheffield, Sheffield, UK., Hind D; Faculty of Medicine and Health, University of Leeds, Leeds, UK., May C; Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, UK., Bianchi S; Sheffield Teaching Hospitals NHS Trust, Sheffield, UK., Cox M; Sheffield Teaching Hospitals NHS Trust, Sheffield, UK., Kaltsakas G; Lane Fox Clinical Respiratory Physiology Centre, Guy's and St Thomas' NHS Foundation Trust, London, UK., Massey C; School of Medicine and Population Health, University of Sheffield, Sheffield, UK.; Sheffield Teaching Hospitals NHS Trust, Sheffield, UK., Mayberry E; School of Medicine and Population Health, University of Sheffield, Sheffield, UK.; Sheffield Teaching Hospitals NHS Trust, Sheffield, UK., Messer B; North East Assisted Ventilation Service, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Needham D; Better Outcomes in MND Patient and Public Involvement Group, School of Medicine and Population Health, University of Sheffield, Sheffield, UK., Playle R; Better Outcomes in MND Patient and Public Involvement Group, School of Medicine and Population Health, University of Sheffield, Sheffield, UK., McDermott C; School of Medicine and Population Health, University of Sheffield, Sheffield, UK.; Sheffield Teaching Hospitals NHS Trust, Sheffield, UK., Griffiths AW; School of Medicine and Population Health, University of Sheffield, Sheffield, UK., Hobson E; School of Medicine and Population Health, University of Sheffield, Sheffield, UK. e.hobson@sheffield.ac.uk.; Sheffield Teaching Hospitals NHS Trust, Sheffield, UK. e.hobson@sheffield.ac.uk.
Source: Implementation science communications [Implement Sci Commun] 2026 Jun 20. Date of Electronic Publication: 2026 Jun 20.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101764360 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-2211 (Electronic) Linking ISSN: 26622211 NLM ISO Abbreviation: Implement Sci Commun
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Girling+C%22">Girling C</searchLink>; School of Medicine and Population Health, University of Sheffield, Sheffield, UK. c.girling@sheffield.ac.uk.<br /><searchLink fieldCode="AU" term="%22Ryan+G%22">Ryan G</searchLink>; School of Medicine and Population Health, University of Sheffield, Sheffield, UK.<br /><searchLink fieldCode="AU" term="%22Bradburn+M%22">Bradburn M</searchLink>; School of Medicine and Population Health, University of Sheffield, Sheffield, UK.<br /><searchLink fieldCode="AU" term="%22Caprioli+T%22">Caprioli T</searchLink>; School of Medicine and Population Health, University of Sheffield, Sheffield, UK.<br /><searchLink fieldCode="AU" term="%22Dawson+S%22">Dawson S</searchLink>; School of Medicine and Population Health, University of Sheffield, Sheffield, UK.<br /><searchLink fieldCode="AU" term="%22Fisher+E%22">Fisher E</searchLink>; School of Medicine and Population Health, University of Sheffield, Sheffield, UK.<br /><searchLink fieldCode="AU" term="%22Haynes+N%22">Haynes N</searchLink>; School of Medicine and Population Health, University of Sheffield, Sheffield, UK.<br /><searchLink fieldCode="AU" term="%22Herbert+E%22">Herbert E</searchLink>; School of Medicine and Population Health, University of Sheffield, Sheffield, UK.<br /><searchLink fieldCode="AU" term="%22Hill+H%22">Hill H</searchLink>; School of Medicine and Population Health, University of Sheffield, Sheffield, UK.<br /><searchLink fieldCode="AU" term="%22Hind+D%22">Hind D</searchLink>; Faculty of Medicine and Health, University of Leeds, Leeds, UK.<br /><searchLink fieldCode="AU" term="%22May+C%22">May C</searchLink>; Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, UK.<br /><searchLink fieldCode="AU" term="%22Bianchi+S%22">Bianchi S</searchLink>; Sheffield Teaching Hospitals NHS Trust, Sheffield, UK.<br /><searchLink fieldCode="AU" term="%22Cox+M%22">Cox M</searchLink>; Sheffield Teaching Hospitals NHS Trust, Sheffield, UK.<br /><searchLink fieldCode="AU" term="%22Kaltsakas+G%22">Kaltsakas G</searchLink>; Lane Fox Clinical Respiratory Physiology Centre, Guy's and St Thomas' NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Massey+C%22">Massey C</searchLink>; School of Medicine and Population Health, University of Sheffield, Sheffield, UK.; Sheffield Teaching Hospitals NHS Trust, Sheffield, UK.<br /><searchLink fieldCode="AU" term="%22Mayberry+E%22">Mayberry E</searchLink>; School of Medicine and Population Health, University of Sheffield, Sheffield, UK.; Sheffield Teaching Hospitals NHS Trust, Sheffield, UK.<br /><searchLink fieldCode="AU" term="%22Messer+B%22">Messer B</searchLink>; North East Assisted Ventilation Service, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Needham+D%22">Needham D</searchLink>; Better Outcomes in MND Patient and Public Involvement Group, School of Medicine and Population Health, University of Sheffield, Sheffield, UK.<br /><searchLink fieldCode="AU" term="%22Playle+R%22">Playle R</searchLink>; Better Outcomes in MND Patient and Public Involvement Group, School of Medicine and Population Health, University of Sheffield, Sheffield, UK.<br /><searchLink fieldCode="AU" term="%22McDermott+C%22">McDermott C</searchLink>; School of Medicine and Population Health, University of Sheffield, Sheffield, UK.; Sheffield Teaching Hospitals NHS Trust, Sheffield, UK.<br /><searchLink fieldCode="AU" term="%22Griffiths+AW%22">Griffiths AW</searchLink>; School of Medicine and Population Health, University of Sheffield, Sheffield, UK.<br /><searchLink fieldCode="AU" term="%22Hobson+E%22">Hobson E</searchLink>; School of Medicine and Population Health, University of Sheffield, Sheffield, UK. e.hobson@sheffield.ac.uk.; Sheffield Teaching Hospitals NHS Trust, Sheffield, UK. e.hobson@sheffield.ac.uk.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101764360 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2662-2211 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226622211%22">26622211 </searchLink><i>NLM ISO Abbreviation: </i>Implement Sci Commun
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              Text: 2026 Jun 20
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