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Cerebrospinal fluid NPTX2/p-tau ratio as a biomarker for cognitive decline in neurodegenerative diseases.

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Title: Cerebrospinal fluid NPTX2/p-tau ratio as a biomarker for cognitive decline in neurodegenerative diseases.
Authors: Gomes BF; Department of Psychiatry and Neurochemistry Institute of Neuroscience and Physiology The Sahlgrenska Academy at the University of Gothenburg Mölndal Sweden., Sauer M; Department of Psychiatry and Neurochemistry Institute of Neuroscience and Physiology The Sahlgrenska Academy at the University of Gothenburg Mölndal Sweden., Montoliu-Gaya L; Department of Psychiatry and Neurochemistry Institute of Neuroscience and Physiology The Sahlgrenska Academy at the University of Gothenburg Mölndal Sweden., Franquesa-Mullerat M; Sant Pau Memory Unit, IR SANT PAU Hospital de la Santa Creu i Sant Pau Barcelona Spain., Bejanin A; Sant Pau Memory Unit, IR SANT PAU Hospital de la Santa Creu i Sant Pau Barcelona Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas CIBERNED Madrid Spain., Alcolea D; Sant Pau Memory Unit, IR SANT PAU Hospital de la Santa Creu i Sant Pau Barcelona Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas CIBERNED Madrid Spain., Lleó A; Sant Pau Memory Unit, IR SANT PAU Hospital de la Santa Creu i Sant Pau Barcelona Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas CIBERNED Madrid Spain., Illán-Gala I; Sant Pau Memory Unit, IR SANT PAU Hospital de la Santa Creu i Sant Pau Barcelona Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas CIBERNED Madrid Spain., Fortea J; Sant Pau Memory Unit, IR SANT PAU Hospital de la Santa Creu i Sant Pau Barcelona Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas CIBERNED Madrid Spain.; Barcelona Down Medical Center Fundació Catalana Síndrome de Down Barcelona Spain., Blennow K; Department of Psychiatry and Neurochemistry Institute of Neuroscience and Physiology The Sahlgrenska Academy at the University of Gothenburg Mölndal Sweden.; Clinical Neurochemistry Laboratory Sahlgrenska University Hospital Mölndal Sweden.; Paris Brain Institute ICM Pitié-Salpêtrière Hospital Sorbonne University Paris France.; Neurodegenerative Disorder Research Center Division of Life Sciences and Medicine and Department of Neurology Institute on Aging and Brain Disorders University of Science and Technology of China and First Affiliated Hospital of USTC Hefei P.R. China., Zetterberg H; Department of Psychiatry and Neurochemistry Institute of Neuroscience and Physiology The Sahlgrenska Academy at the University of Gothenburg Mölndal Sweden.; Clinical Neurochemistry Laboratory Sahlgrenska University Hospital Mölndal Sweden.; Department of Neurodegenerative Disease UCL Institute of Neurology London UK.; UK Dementia Research Institute at UCL London UK.; Hong Kong Center for Neurodegenerative Diseases Clear Water Bay Hong Kong China.; Wisconsin Alzheimer's Disease Research Center University of Wisconsin School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA., Nilsson J; Department of Psychiatry and Neurochemistry Institute of Neuroscience and Physiology The Sahlgrenska Academy at the University of Gothenburg Mölndal Sweden., Belbin O; Sant Pau Memory Unit, IR SANT PAU Hospital de la Santa Creu i Sant Pau Barcelona Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas CIBERNED Madrid Spain., Ashton NJ; Department of Psychiatry and Neurochemistry Institute of Neuroscience and Physiology The Sahlgrenska Academy at the University of Gothenburg Mölndal Sweden.; Banner Alzheimer's Institute and University of Arizona Phoenix Arizona USA.; Banner Sun Health Research Institute Sun City Arizona USA.
Source: Alzheimer's & dementia (Amsterdam, Netherlands) [Alzheimers Dement (Amst)] 2026 Jun 18; Vol. 18 (2), pp. e70391. Date of Electronic Publication: 2026 Jun 18 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Wiley on behalf of the Alzheimer's Association Country of Publication: United States NLM ID: 101654604 Publication Model: eCollection Cited Medium: Print ISSN: 2352-8729 (Print) Linking ISSN: 23528729 NLM ISO Abbreviation: Alzheimers Dement (Amst) Subsets: PubMed not MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Gomes+BF%22">Gomes BF</searchLink>; Department of Psychiatry and Neurochemistry Institute of Neuroscience and Physiology The Sahlgrenska Academy at the University of Gothenburg Mölndal Sweden.<br /><searchLink fieldCode="AU" term="%22Sauer+M%22">Sauer M</searchLink>; Department of Psychiatry and Neurochemistry Institute of Neuroscience and Physiology The Sahlgrenska Academy at the University of Gothenburg Mölndal Sweden.<br /><searchLink fieldCode="AU" term="%22Montoliu-Gaya+L%22">Montoliu-Gaya L</searchLink>; Department of Psychiatry and Neurochemistry Institute of Neuroscience and Physiology The Sahlgrenska Academy at the University of Gothenburg Mölndal Sweden.<br /><searchLink fieldCode="AU" term="%22Franquesa-Mullerat+M%22">Franquesa-Mullerat M</searchLink>; Sant Pau Memory Unit, IR SANT PAU Hospital de la Santa Creu i Sant Pau Barcelona Spain.<br /><searchLink fieldCode="AU" term="%22Bejanin+A%22">Bejanin A</searchLink>; Sant Pau Memory Unit, IR SANT PAU Hospital de la Santa Creu i Sant Pau Barcelona Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas CIBERNED Madrid Spain.<br /><searchLink fieldCode="AU" term="%22Alcolea+D%22">Alcolea D</searchLink>; Sant Pau Memory Unit, IR SANT PAU Hospital de la Santa Creu i Sant Pau Barcelona Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas CIBERNED Madrid Spain.<br /><searchLink fieldCode="AU" term="%22Lleó+A%22">Lleó A</searchLink>; Sant Pau Memory Unit, IR SANT PAU Hospital de la Santa Creu i Sant Pau Barcelona Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas CIBERNED Madrid Spain.<br /><searchLink fieldCode="AU" term="%22Illán-Gala+I%22">Illán-Gala I</searchLink>; Sant Pau Memory Unit, IR SANT PAU Hospital de la Santa Creu i Sant Pau Barcelona Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas CIBERNED Madrid Spain.<br /><searchLink fieldCode="AU" term="%22Fortea+J%22">Fortea J</searchLink>; Sant Pau Memory Unit, IR SANT PAU Hospital de la Santa Creu i Sant Pau Barcelona Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas CIBERNED Madrid Spain.; Barcelona Down Medical Center Fundació Catalana Síndrome de Down Barcelona Spain.<br /><searchLink fieldCode="AU" term="%22Blennow+K%22">Blennow K</searchLink>; Department of Psychiatry and Neurochemistry Institute of Neuroscience and Physiology The Sahlgrenska Academy at the University of Gothenburg Mölndal Sweden.; Clinical Neurochemistry Laboratory Sahlgrenska University Hospital Mölndal Sweden.; Paris Brain Institute ICM Pitié-Salpêtrière Hospital Sorbonne University Paris France.; Neurodegenerative Disorder Research Center Division of Life Sciences and Medicine and Department of Neurology Institute on Aging and Brain Disorders University of Science and Technology of China and First Affiliated Hospital of USTC Hefei P.R. China.<br /><searchLink fieldCode="AU" term="%22Zetterberg+H%22">Zetterberg H</searchLink>; Department of Psychiatry and Neurochemistry Institute of Neuroscience and Physiology The Sahlgrenska Academy at the University of Gothenburg Mölndal Sweden.; Clinical Neurochemistry Laboratory Sahlgrenska University Hospital Mölndal Sweden.; Department of Neurodegenerative Disease UCL Institute of Neurology London UK.; UK Dementia Research Institute at UCL London UK.; Hong Kong Center for Neurodegenerative Diseases Clear Water Bay Hong Kong China.; Wisconsin Alzheimer's Disease Research Center University of Wisconsin School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA.<br /><searchLink fieldCode="AU" term="%22Nilsson+J%22">Nilsson J</searchLink>; Department of Psychiatry and Neurochemistry Institute of Neuroscience and Physiology The Sahlgrenska Academy at the University of Gothenburg Mölndal Sweden.<br /><searchLink fieldCode="AU" term="%22Belbin+O%22">Belbin O</searchLink>; Sant Pau Memory Unit, IR SANT PAU Hospital de la Santa Creu i Sant Pau Barcelona Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas CIBERNED Madrid Spain.<br /><searchLink fieldCode="AU" term="%22Ashton+NJ%22">Ashton NJ</searchLink>; Department of Psychiatry and Neurochemistry Institute of Neuroscience and Physiology The Sahlgrenska Academy at the University of Gothenburg Mölndal Sweden.; Banner Alzheimer's Institute and University of Arizona Phoenix Arizona USA.; Banner Sun Health Research Institute Sun City Arizona USA.
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  Data: <searchLink fieldCode="JN" term="%22101654604%22">Alzheimer's & dementia (Amsterdam, Netherlands)</searchLink> [Alzheimers Dement (Amst)] 2026 Jun 18; Vol. 18 (2), pp. e70391. <i>Date of Electronic Publication: </i>2026 Jun 18 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley+on+behalf+of+the+Alzheimer's+Association%22">Wiley on behalf of the Alzheimer's Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101654604 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2352-8729 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223528729%22">23528729 </searchLink><i>NLM ISO Abbreviation: </i>Alzheimers Dement (Amst) <i>Subsets: </i>PubMed not MEDLINE
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