Carob pod aqueous extract potentiates cisplatin efficacy and reduces toxicity in experimental hepatocellular carcinoma via mitochondrial and inflammatory pathway modulation.
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| Title: | Carob pod aqueous extract potentiates cisplatin efficacy and reduces toxicity in experimental hepatocellular carcinoma via mitochondrial and inflammatory pathway modulation. |
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| Authors: | Darwish WS; Chemistry Department, Faculty of Science, Menoufia University, Shibin el Kom, Menoufia, 32511, Egypt.; Department of Basic Science, College of Dentistry, Al Maaqal University, Al Basrah, 61003, Iraq., El Sayed Khadr A; Chemistry Department, Faculty of Science, Menoufia University, Shibin el Kom, Menoufia, 32511, Egypt., Abd El Naby Kamel M; Biochemistry Department, Medical Research Institute, Alexandria University, Alexandria, 21561, Egypt.; Research Projects unit, Pharos University in Alexandria, Alexandria, 21648, Egypt., Addissouky TA; Chemistry Department, Faculty of Science, Menoufia University, Shibin el Kom, Menoufia, 32511, Egypt. tedesoky@gmail.com.; New Burg El-Arab Hospital, Ministry of Health, Alexandria, Egypt. tedesoky@gmail.com., Ghareeb AZ; Center of Excellence for Drug Preclinical studies (CE-DPS), Pharmaceutical and Fermentation Industries Development Center (PFIDC), City of Scientific Research & Technological Applications (SRTA-City), New Borg El Arab, Egypt.; Egypt Center for Research and Regenerative Medicine (ECRRM), Cairo, Egypt., Eldaim MAA; Department of Biochemistry and Molecular Biology, Faculty of Veterinary Medicine, Menoufia University, Menoufia, 32511, Egypt.; Department of Biochemistry and Molecular Biology, Faculty of Veterinary 10. Medicine, Menoufia National University, Birket El Sabaa, Menoufia, Egypt., Razzaq MK; Department of Biochemistry, College of Medicine, University of Sumer, Thi-Qar, Iraq., El Tantawy El Sayed I; Chemistry Department, Faculty of Science, Menoufia University, Shibin el Kom, Menoufia, 32511, Egypt., Abdel-Bary HM; Chemistry Department, Faculty of Science, Menoufia University, Shibin el Kom, Menoufia, 32511, Egypt., Ghareeb DA; Research Projects unit, Pharos University in Alexandria, Alexandria, 21648, Egypt.; Center of Excellence for Drug Preclinical studies (CE-DPS), Pharmaceutical and Fermentation Industries Development Center (PFIDC), City of Scientific Research & Technological Applications (SRTA-City), New Borg El Arab, Egypt.; Bio-Screening and Preclinical Trial Lab, Biochemistry Department, Faculty of Science, Alexandria University, Alexandria, Egypt. |
| Source: | Bioresources and bioprocessing [Bioresour Bioprocess] 2026 Jun 22; Vol. 13 (1). Date of Electronic Publication: 2026 Jun 22. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer-Verlag, GmbH Country of Publication: Germany NLM ID: 101665551 Publication Model: Electronic Cited Medium: Internet ISSN: 2197-4365 (Electronic) Linking ISSN: 21974365 NLM ISO Abbreviation: Bioresour Bioprocess Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42329491 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Carob pod aqueous extract potentiates cisplatin efficacy and reduces toxicity in experimental hepatocellular carcinoma via mitochondrial and inflammatory pathway modulation. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Darwish+WS%22">Darwish WS</searchLink>; Chemistry Department, Faculty of Science, Menoufia University, Shibin el Kom, Menoufia, 32511, Egypt.; Department of Basic Science, College of Dentistry, Al Maaqal University, Al Basrah, 61003, Iraq.<br /><searchLink fieldCode="AU" term="%22El+Sayed+Khadr+A%22">El Sayed Khadr A</searchLink>; Chemistry Department, Faculty of Science, Menoufia University, Shibin el Kom, Menoufia, 32511, Egypt.<br /><searchLink fieldCode="AU" term="%22Abd+El+Naby+Kamel+M%22">Abd El Naby Kamel M</searchLink>; Biochemistry Department, Medical Research Institute, Alexandria University, Alexandria, 21561, Egypt.; Research Projects unit, Pharos University in Alexandria, Alexandria, 21648, Egypt.<br /><searchLink fieldCode="AU" term="%22Addissouky+TA%22">Addissouky TA</searchLink>; Chemistry Department, Faculty of Science, Menoufia University, Shibin el Kom, Menoufia, 32511, Egypt. tedesoky@gmail.com.; New Burg El-Arab Hospital, Ministry of Health, Alexandria, Egypt. tedesoky@gmail.com.<br /><searchLink fieldCode="AU" term="%22Ghareeb+AZ%22">Ghareeb AZ</searchLink>; Center of Excellence for Drug Preclinical studies (CE-DPS), Pharmaceutical and Fermentation Industries Development Center (PFIDC), City of Scientific Research & Technological Applications (SRTA-City), New Borg El Arab, Egypt.; Egypt Center for Research and Regenerative Medicine (ECRRM), Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22Eldaim+MAA%22">Eldaim MAA</searchLink>; Department of Biochemistry and Molecular Biology, Faculty of Veterinary Medicine, Menoufia University, Menoufia, 32511, Egypt.; Department of Biochemistry and Molecular Biology, Faculty of Veterinary 10. Medicine, Menoufia National University, Birket El Sabaa, Menoufia, Egypt.<br /><searchLink fieldCode="AU" term="%22Razzaq+MK%22">Razzaq MK</searchLink>; Department of Biochemistry, College of Medicine, University of Sumer, Thi-Qar, Iraq.<br /><searchLink fieldCode="AU" term="%22El+Tantawy+El+Sayed+I%22">El Tantawy El Sayed I</searchLink>; Chemistry Department, Faculty of Science, Menoufia University, Shibin el Kom, Menoufia, 32511, Egypt.<br /><searchLink fieldCode="AU" term="%22Abdel-Bary+HM%22">Abdel-Bary HM</searchLink>; Chemistry Department, Faculty of Science, Menoufia University, Shibin el Kom, Menoufia, 32511, Egypt.<br /><searchLink fieldCode="AU" term="%22Ghareeb+DA%22">Ghareeb DA</searchLink>; Research Projects unit, Pharos University in Alexandria, Alexandria, 21648, Egypt.; Center of Excellence for Drug Preclinical studies (CE-DPS), Pharmaceutical and Fermentation Industries Development Center (PFIDC), City of Scientific Research & Technological Applications (SRTA-City), New Borg El Arab, Egypt.; Bio-Screening and Preclinical Trial Lab, Biochemistry Department, Faculty of Science, Alexandria University, Alexandria, Egypt. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101665551%22">Bioresources and bioprocessing</searchLink> [Bioresour Bioprocess] 2026 Jun 22; Vol. 13 (1). <i>Date of Electronic Publication: </i>2026 Jun 22. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer-Verlag%2C+GmbH%22">Springer-Verlag, GmbH </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101665551 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2197-4365 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221974365%22">21974365 </searchLink><i>NLM ISO Abbreviation: </i>Bioresour Bioprocess <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42329491 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1186/s40643-026-01029-0 Languages: – Code: eng Text: English Titles: – TitleFull: Carob pod aqueous extract potentiates cisplatin efficacy and reduces toxicity in experimental hepatocellular carcinoma via mitochondrial and inflammatory pathway modulation. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Darwish WS – PersonEntity: Name: NameFull: El Sayed Khadr A – PersonEntity: Name: NameFull: Abd El Naby Kamel M – PersonEntity: Name: NameFull: Addissouky TA – PersonEntity: Name: NameFull: Ghareeb AZ – PersonEntity: Name: NameFull: Eldaim MAA – PersonEntity: Name: NameFull: Razzaq MK – PersonEntity: Name: NameFull: El Tantawy El Sayed I – PersonEntity: Name: NameFull: Abdel-Bary HM – PersonEntity: Name: NameFull: Ghareeb DA IsPartOfRelationships: – BibEntity: Dates: – D: 22 M: 06 Text: 2026 Jun 22 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2197-4365 Numbering: – Type: volume Value: 13 – Type: issue Value: 1 Titles: – TitleFull: Bioresources and bioprocessing Type: main |
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