Integrated risk characterization of estragole, aristolochic acids, and pyrrolizidine alkaloids in natural products using margin of exposure and RISK21.
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| Title: | Integrated risk characterization of estragole, aristolochic acids, and pyrrolizidine alkaloids in natural products using margin of exposure and RISK21. |
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| Authors: | Pauzi NAM; Herbal Medicine Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia, 40170, Shah Alam, Selangor, Malaysia. nurazra@moh.gov.my.; Department of Environmental and Occupational Health, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia. nurazra@moh.gov.my., Razali MF; Department of Environmental and Occupational Health, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.; Institute for Public Health, National Institutes of Health, Ministry of Health Malaysia, 40170, Shah Alam, Selangor, Malaysia., Aziz MY; Advanced Medical and Dental Institute, Universiti Sains Malaysia, 13200, Kepala Batas, Pulau Pinang, Malaysia., Mirad R; Agrobiodiversity and Environment Research Center, Genebank Complex, MARDI Headquarter, 43400, Serdang, Selangor, Malaysia., Cheema MS; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia., Ismail A; Department of Nutrition, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia., Ghazali AR; Centre for Toxicology and Health Risk Studies, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, 50300, Kuala Lumpur, Malaysia., Abdullah R; Department of Environmental and Occupational Health, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia. |
| Source: | Scientific reports [Sci Rep] 2026 Jun 22. Date of Electronic Publication: 2026 Jun 22. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42332081 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Integrated risk characterization of estragole, aristolochic acids, and pyrrolizidine alkaloids in natural products using margin of exposure and RISK21. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Pauzi+NAM%22">Pauzi NAM</searchLink>; Herbal Medicine Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia, 40170, Shah Alam, Selangor, Malaysia. nurazra@moh.gov.my.; Department of Environmental and Occupational Health, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia. nurazra@moh.gov.my.<br /><searchLink fieldCode="AU" term="%22Razali+MF%22">Razali MF</searchLink>; Department of Environmental and Occupational Health, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.; Institute for Public Health, National Institutes of Health, Ministry of Health Malaysia, 40170, Shah Alam, Selangor, Malaysia.<br /><searchLink fieldCode="AU" term="%22Aziz+MY%22">Aziz MY</searchLink>; Advanced Medical and Dental Institute, Universiti Sains Malaysia, 13200, Kepala Batas, Pulau Pinang, Malaysia.<br /><searchLink fieldCode="AU" term="%22Mirad+R%22">Mirad R</searchLink>; Agrobiodiversity and Environment Research Center, Genebank Complex, MARDI Headquarter, 43400, Serdang, Selangor, Malaysia.<br /><searchLink fieldCode="AU" term="%22Cheema+MS%22">Cheema MS</searchLink>; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.<br /><searchLink fieldCode="AU" term="%22Ismail+A%22">Ismail A</searchLink>; Department of Nutrition, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.<br /><searchLink fieldCode="AU" term="%22Ghazali+AR%22">Ghazali AR</searchLink>; Centre for Toxicology and Health Risk Studies, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, 50300, Kuala Lumpur, Malaysia.<br /><searchLink fieldCode="AU" term="%22Abdullah+R%22">Abdullah R</searchLink>; Department of Environmental and Occupational Health, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2026 Jun 22. <i>Date of Electronic Publication: </i>2026 Jun 22. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101563288 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2045-2322 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220452322%22">20452322 </searchLink><i>NLM ISO Abbreviation: </i>Sci Rep <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42332081 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41598-026-56929-0 Languages: – Code: eng Text: English Titles: – TitleFull: Integrated risk characterization of estragole, aristolochic acids, and pyrrolizidine alkaloids in natural products using margin of exposure and RISK21. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Pauzi NAM – PersonEntity: Name: NameFull: Razali MF – PersonEntity: Name: NameFull: Aziz MY – PersonEntity: Name: NameFull: Mirad R – PersonEntity: Name: NameFull: Cheema MS – PersonEntity: Name: NameFull: Ismail A – PersonEntity: Name: NameFull: Ghazali AR – PersonEntity: Name: NameFull: Abdullah R IsPartOfRelationships: – BibEntity: Dates: – D: 22 M: 06 Text: 2026 Jun 22 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2045-2322 Titles: – TitleFull: Scientific reports Type: main |
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