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Derivation of elephant induced pluripotent stem cells.

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Title: Derivation of elephant induced pluripotent stem cells.
Authors: Appleton E; Colossal Biosciences, Dallas, TX, USA. evan.appleton@gmail.com., Korover N; Colossal Biosciences, Dallas, TX, USA., Hong K; Colossal Biosciences, Dallas, TX, USA., Ambriz-Peña X; Colossal Biosciences, Dallas, TX, USA., Tanaka Y; Colossal Biosciences, Dallas, TX, USA.; Maisonneuve-Rosemont Hospital Research Center, Department of Medicine, University of Montreal, Montreal, Quebec, Canada., Ashkenazy-Titelman A; Department of Genetics, Harvard Medical School, Boston, MA, USA., Rasmussen-Ivey C; Colossal Biosciences, Dallas, TX, USA., Rodríguez-Caycedo C; Colossal Biosciences, Dallas, TX, USA., Bhide K; FormBio, Dallas, TX, USA., Bai H; Colossal Biosciences, Dallas, TX, USA., Queiroz A; Department of Genetics, Harvard Medical School, Boston, MA, USA., Nelson JW; Colossal Biosciences, Dallas, TX, USA., Rathod G; Colossal Biosciences, Dallas, TX, USA., Morgan M; Colossal Biosciences, Dallas, TX, USA., Mastracci A; Colossal Biosciences, Dallas, TX, USA., Nelson TM; Department of Physiology and Biophysics and the WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, New York, NY, USA., Knox G; Colossal Biosciences, Dallas, TX, USA., McNutt B; FormBio, Dallas, TX, USA., Malviya N; Colossal Biosciences, Dallas, TX, USA., Zhang K; Colossal Biosciences, Dallas, TX, USA., Kowalczyk A; FormBio, Dallas, TX, USA., Bow A; Colossal Biosciences, Dallas, TX, USA., McLendon B; Colossal Biosciences, Dallas, TX, USA., Slamecka J; Colossal Biosciences, Dallas, TX, USA., Ryon K; Department of Physiology and Biophysics and the WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, New York, NY, USA., Proszynski J; Department of Physiology and Biophysics and the WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, New York, NY, USA., Houerbi N; Department of Physiology and Biophysics and the WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, New York, NY, USA., Kleinman AS; Department of Physiology and Biophysics and the WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, New York, NY, USA., Poon CL; Department of Physiology and Biophysics and the WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, New York, NY, USA.; Computational Oncology Service, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Kiso W; Colossal Biosciences, Dallas, TX, USA., James M; Colossal Biosciences, Dallas, TX, USA., Park IH; Department of Genetics and Neuroscience, Yale Stem Cell Center, Yale University, New Haven, CT, USA., Gray C; African Lion Safari, Hamilton, Ontario, Canada., Pearson VR; Fox Chase Cancer Center, Philadelphia, PA, USA., Mason CE; Department of Physiology and Biophysics and the WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, New York, NY, USA.; The Trivedi Institute of Space and Global Biomedicine, Pittsburgh, PA, USA., Cantarel BL; Colossal Biosciences, Dallas, TX, USA.; FormBio, Dallas, TX, USA., Koehler KR; Departments of Department of Otolaryngology - Head and Neck Surgery, Harvard Medical School, Boston, MA, USA.; Departments of Otolaryngology, Plastic and Oral Surgery, and the F.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA., Shapiro B; Colossal Biosciences, Dallas, TX, USA., Kehler J; Colossal Biosciences, Dallas, TX, USA.; UT Southwestern Medical Center, Dallas, TX, USA., Lamm B; Colossal Biosciences, Dallas, TX, USA.; FormBio, Dallas, TX, USA., Church G; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA, USA., Hysolli E; Colossal Biosciences, Dallas, TX, USA. eriona.hysolli@gmail.com.
Source: Nature methods [Nat Methods] 2026 Jun 22. Date of Electronic Publication: 2026 Jun 22.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101215604 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1548-7105 (Electronic) Linking ISSN: 15487091 NLM ISO Abbreviation: Nat Methods Subsets: MEDLINE
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Department of Physiology and Biophysics and the WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, New York, NY, USA.; The Trivedi Institute of Space and Global Biomedicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Cantarel+BL%22">Cantarel BL</searchLink>; Colossal Biosciences, Dallas, TX, USA.; FormBio, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Koehler+KR%22">Koehler KR</searchLink>; Departments of Department of Otolaryngology - Head and Neck Surgery, Harvard Medical School, Boston, MA, USA.; Departments of Otolaryngology, Plastic and Oral Surgery, and the F.M. 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