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Engineered Bacillus subtilis for high-yield nattokinase production and therapeutic potential in obesity management.

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Title: Engineered Bacillus subtilis for high-yield nattokinase production and therapeutic potential in obesity management.
Authors: Liu Y; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, National Technology Innovation Center of Synthetic Biology, No. 32, Xiqi Road, Tianjin Airport Economic Park, Tianjin, 300308, China.; Zhang Zhongjing College of Chinese Medicine, Nanyang Institute of Technology, Nanyang, China., Zhu L; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, National Technology Innovation Center of Synthetic Biology, No. 32, Xiqi Road, Tianjin Airport Economic Park, Tianjin, 300308, China., Yao T; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, National Technology Innovation Center of Synthetic Biology, No. 32, Xiqi Road, Tianjin Airport Economic Park, Tianjin, 300308, China., Wang Y; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, National Technology Innovation Center of Synthetic Biology, No. 32, Xiqi Road, Tianjin Airport Economic Park, Tianjin, 300308, China., Xie C; Tianjin Key Laboratory of Animal Molecular Breeding and Biotechnology, Tianjin Livestock and Poultry Health Breeding Technology Engineering Center, Institute of Animal Science and Veterinary, Tianjin Academy of Agricultural Sciences, Tianjin, 300381, China. xie.chunyan@foxmail.com., Gao L; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, National Technology Innovation Center of Synthetic Biology, No. 32, Xiqi Road, Tianjin Airport Economic Park, Tianjin, 300308, China. gao_l@tib.cas.cn.
Source: Journal of animal science and biotechnology [J Anim Sci Biotechnol] 2026 Jun 23; Vol. 17 (1). Date of Electronic Publication: 2026 Jun 23.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101581293 Publication Model: Electronic Cited Medium: Print ISSN: 1674-9782 (Print) Linking ISSN: 16749782 NLM ISO Abbreviation: J Anim Sci Biotechnol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Engineered Bacillus subtilis for high-yield nattokinase production and therapeutic potential in obesity management.
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  Data: <searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, National Technology Innovation Center of Synthetic Biology, No. 32, Xiqi Road, Tianjin Airport Economic Park, Tianjin, 300308, China.; Zhang Zhongjing College of Chinese Medicine, Nanyang Institute of Technology, Nanyang, China.<br /><searchLink fieldCode="AU" term="%22Zhu+L%22">Zhu L</searchLink>; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, National Technology Innovation Center of Synthetic Biology, No. 32, Xiqi Road, Tianjin Airport Economic Park, Tianjin, 300308, China.<br /><searchLink fieldCode="AU" term="%22Yao+T%22">Yao T</searchLink>; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, National Technology Innovation Center of Synthetic Biology, No. 32, Xiqi Road, Tianjin Airport Economic Park, Tianjin, 300308, China.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, National Technology Innovation Center of Synthetic Biology, No. 32, Xiqi Road, Tianjin Airport Economic Park, Tianjin, 300308, China.<br /><searchLink fieldCode="AU" term="%22Xie+C%22">Xie C</searchLink>; Tianjin Key Laboratory of Animal Molecular Breeding and Biotechnology, Tianjin Livestock and Poultry Health Breeding Technology Engineering Center, Institute of Animal Science and Veterinary, Tianjin Academy of Agricultural Sciences, Tianjin, 300381, China. xie.chunyan@foxmail.com.<br /><searchLink fieldCode="AU" term="%22Gao+L%22">Gao L</searchLink>; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, National Technology Innovation Center of Synthetic Biology, No. 32, Xiqi Road, Tianjin Airport Economic Park, Tianjin, 300308, China. gao_l@tib.cas.cn.
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  Data: <searchLink fieldCode="JN" term="%22101581293%22">Journal of animal science and biotechnology</searchLink> [J Anim Sci Biotechnol] 2026 Jun 23; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Jun 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101581293 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>1674-9782 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216749782%22">16749782 </searchLink><i>NLM ISO Abbreviation: </i>J Anim Sci Biotechnol <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1186/s40104-026-01438-3
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      – Code: eng
        Text: English
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      – TitleFull: Engineered Bacillus subtilis for high-yield nattokinase production and therapeutic potential in obesity management.
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            NameFull: Liu Y
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            NameFull: Zhu L
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            NameFull: Yao T
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            NameFull: Wang Y
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            NameFull: Xie C
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            – D: 23
              M: 06
              Text: 2026 Jun 23
              Type: published
              Y: 2026
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              Value: 1674-9782
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              Value: 17
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            – TitleFull: Journal of animal science and biotechnology
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