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Asymmetric Synthesis of α-Aryl α-Amino Acids via NHC-Catalyzed Dynamic Kinetic Resolution.

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Title: Asymmetric Synthesis of α-Aryl α-Amino Acids via NHC-Catalyzed Dynamic Kinetic Resolution.
Authors: Li HG; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.; University of Chinese Academy of Sciences, Beijing 100049, P. R. China., Jiang LL; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.; College of Chemistry and Chemical Engineering and Key (Guangdong-Hong Kong Joint) Laboratory for Preparation and Application of Ordered Structural Materials of Guangdong Province, Shantou University, Shantou 515063, P. R. China., Li JL; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.; University of Chinese Academy of Sciences, Beijing 100049, P. R. China., Wang XY; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.; University of Chinese Academy of Sciences, Beijing 100049, P. R. China., Deng X; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.; University of Chinese Academy of Sciences, Beijing 100049, P. R. China., Zhu CM; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.; University of Chinese Academy of Sciences, Beijing 100049, P. R. China., Li CB; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.; University of Chinese Academy of Sciences, Beijing 100049, P. R. China., Li HY; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.; University of Chinese Academy of Sciences, Beijing 100049, P. R. China., Zhong JJ; College of Chemistry and Chemical Engineering and Key (Guangdong-Hong Kong Joint) Laboratory for Preparation and Application of Ordered Structural Materials of Guangdong Province, Shantou University, Shantou 515063, P. R. China., Ye S; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.; University of Chinese Academy of Sciences, Beijing 100049, P. R. China., Gao ZH; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.; University of Chinese Academy of Sciences, Beijing 100049, P. R. China., Meng QY; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.; University of Chinese Academy of Sciences, Beijing 100049, P. R. China.
Source: Organic letters [Org Lett] 2026 Jun 22. Date of Electronic Publication: 2026 Jun 22.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 100890393 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-7052 (Electronic) Linking ISSN: 15237052 NLM ISO Abbreviation: Org Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Asymmetric Synthesis of α-Aryl α-Amino Acids via NHC-Catalyzed Dynamic Kinetic Resolution.
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  Data: <searchLink fieldCode="AU" term="%22Li+HG%22">Li HG</searchLink>; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.; University of Chinese Academy of Sciences, Beijing 100049, P. R. China.<br /><searchLink fieldCode="AU" term="%22Jiang+LL%22">Jiang LL</searchLink>; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.; College of Chemistry and Chemical Engineering and Key (Guangdong-Hong Kong Joint) Laboratory for Preparation and Application of Ordered Structural Materials of Guangdong Province, Shantou University, Shantou 515063, P. R. China.<br /><searchLink fieldCode="AU" term="%22Li+JL%22">Li JL</searchLink>; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.; University of Chinese Academy of Sciences, Beijing 100049, P. R. China.<br /><searchLink fieldCode="AU" term="%22Wang+XY%22">Wang XY</searchLink>; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.; University of Chinese Academy of Sciences, Beijing 100049, P. R. China.<br /><searchLink fieldCode="AU" term="%22Deng+X%22">Deng X</searchLink>; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.; University of Chinese Academy of Sciences, Beijing 100049, P. R. China.<br /><searchLink fieldCode="AU" term="%22Zhu+CM%22">Zhu CM</searchLink>; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.; University of Chinese Academy of Sciences, Beijing 100049, P. R. China.<br /><searchLink fieldCode="AU" term="%22Li+CB%22">Li CB</searchLink>; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.; University of Chinese Academy of Sciences, Beijing 100049, P. R. China.<br /><searchLink fieldCode="AU" term="%22Li+HY%22">Li HY</searchLink>; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.; University of Chinese Academy of Sciences, Beijing 100049, P. R. China.<br /><searchLink fieldCode="AU" term="%22Zhong+JJ%22">Zhong JJ</searchLink>; College of Chemistry and Chemical Engineering and Key (Guangdong-Hong Kong Joint) Laboratory for Preparation and Application of Ordered Structural Materials of Guangdong Province, Shantou University, Shantou 515063, P. R. China.<br /><searchLink fieldCode="AU" term="%22Ye+S%22">Ye S</searchLink>; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.; University of Chinese Academy of Sciences, Beijing 100049, P. R. China.<br /><searchLink fieldCode="AU" term="%22Gao+ZH%22">Gao ZH</searchLink>; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.; University of Chinese Academy of Sciences, Beijing 100049, P. R. China.<br /><searchLink fieldCode="AU" term="%22Meng+QY%22">Meng QY</searchLink>; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.; University of Chinese Academy of Sciences, Beijing 100049, P. R. China.
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        Value: 10.1021/acs.orglett.6c02179
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        Text: English
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      – TitleFull: Asymmetric Synthesis of α-Aryl α-Amino Acids via NHC-Catalyzed Dynamic Kinetic Resolution.
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              M: 06
              Text: 2026 Jun 22
              Type: published
              Y: 2026
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