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Exploring the mechanism of action of Qufengzhitong pills in treating rheumatoid arthritis via the PI3K/AKT, NF-κB, and MAPK pathways.

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Title: Exploring the mechanism of action of Qufengzhitong pills in treating rheumatoid arthritis via the PI3K/AKT, NF-κB, and MAPK pathways.
Authors: Li J; School of Pharmacy, Wannan Medical University, Wuhu, Anhui 241002, China.; School of Biological and Food Engineering, Engineering Research Center for Development and High Value Utilization of Genuine Medicinal Materials in North Anhui Province, Suzhou University, Suzhou, Anhui 234000, China., Li R; School of Biological and Food Engineering, Engineering Research Center for Development and High Value Utilization of Genuine Medicinal Materials in North Anhui Province, Suzhou University, Suzhou, Anhui 234000, China., Wang Y; School of Biological and Food Engineering, Engineering Research Center for Development and High Value Utilization of Genuine Medicinal Materials in North Anhui Province, Suzhou University, Suzhou, Anhui 234000, China., Rashed MMA; School of Biological and Food Engineering, Engineering Research Center for Development and High Value Utilization of Genuine Medicinal Materials in North Anhui Province, Suzhou University, Suzhou, Anhui 234000, China., Qi D; School of Biological and Food Engineering, Engineering Research Center for Development and High Value Utilization of Genuine Medicinal Materials in North Anhui Province, Suzhou University, Suzhou, Anhui 234000, China., He Y; School of Biological and Food Engineering, Engineering Research Center for Development and High Value Utilization of Genuine Medicinal Materials in North Anhui Province, Suzhou University, Suzhou, Anhui 234000, China., He C; Xinjiang Institute of Materia Medica, Key Laboratory of Xinjiang Uygur Medicine, Urumqi, Xinjiang Uygur Autonomous Region 830010, China., Chang Y; State Key Laboratory of Chinese Medicine Modernization, Tianjin University of Traditional Chinese Medicine, Tianjin, Tianjin Municipality 301617, China., Nian S; School of Pharmacy, Wannan Medical University, Wuhu, Anhui 241002, China., Duan H; School of Biological and Food Engineering, Engineering Research Center for Development and High Value Utilization of Genuine Medicinal Materials in North Anhui Province, Suzhou University, Suzhou, Anhui 234000, China., Hu H; General Clinical Research Center, Anhui Wanbei Coal-Electricity Group General Hospital, Suzhou, Anhui Province 234000,  China., Zhai K; School of Pharmacy, Wannan Medical University, Wuhu, Anhui 241002, China.; School of Biological and Food Engineering, Engineering Research Center for Development and High Value Utilization of Genuine Medicinal Materials in North Anhui Province, Suzhou University, Suzhou, Anhui 234000, China.
Source: The Journal of pharmacy and pharmacology [J Pharm Pharmacol] 2026 Jun 02; Vol. 78 (6).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0376363 Publication Model: Print Cited Medium: Internet ISSN: 2042-7158 (Electronic) Linking ISSN: 00223573 NLM ISO Abbreviation: J Pharm Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; School of Pharmacy, Wannan Medical University, Wuhu, Anhui 241002, China.; School of Biological and Food Engineering, Engineering Research Center for Development and High Value Utilization of Genuine Medicinal Materials in North Anhui Province, Suzhou University, Suzhou, Anhui 234000, China.<br /><searchLink fieldCode="AU" term="%22Li+R%22">Li R</searchLink>; School of Biological and Food Engineering, Engineering Research Center for Development and High Value Utilization of Genuine Medicinal Materials in North Anhui Province, Suzhou University, Suzhou, Anhui 234000, China.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; School of Biological and Food Engineering, Engineering Research Center for Development and High Value Utilization of Genuine Medicinal Materials in North Anhui Province, Suzhou University, Suzhou, Anhui 234000, China.<br /><searchLink fieldCode="AU" term="%22Rashed+MMA%22">Rashed MMA</searchLink>; School of Biological and Food Engineering, Engineering Research Center for Development and High Value Utilization of Genuine Medicinal Materials in North Anhui Province, Suzhou University, Suzhou, Anhui 234000, China.<br /><searchLink fieldCode="AU" term="%22Qi+D%22">Qi D</searchLink>; School of Biological and Food Engineering, Engineering Research Center for Development and High Value Utilization of Genuine Medicinal Materials in North Anhui Province, Suzhou University, Suzhou, Anhui 234000, China.<br /><searchLink fieldCode="AU" term="%22He+Y%22">He Y</searchLink>; School of Biological and Food Engineering, Engineering Research Center for Development and High Value Utilization of Genuine Medicinal Materials in North Anhui Province, Suzhou University, Suzhou, Anhui 234000, China.<br /><searchLink fieldCode="AU" term="%22He+C%22">He C</searchLink>; Xinjiang Institute of Materia Medica, Key Laboratory of Xinjiang Uygur Medicine, Urumqi, Xinjiang Uygur Autonomous Region 830010, China.<br /><searchLink fieldCode="AU" term="%22Chang+Y%22">Chang Y</searchLink>; State Key Laboratory of Chinese Medicine Modernization, Tianjin University of Traditional Chinese Medicine, Tianjin, Tianjin Municipality 301617, China.<br /><searchLink fieldCode="AU" term="%22Nian+S%22">Nian S</searchLink>; School of Pharmacy, Wannan Medical University, Wuhu, Anhui 241002, China.<br /><searchLink fieldCode="AU" term="%22Duan+H%22">Duan H</searchLink>; School of Biological and Food Engineering, Engineering Research Center for Development and High Value Utilization of Genuine Medicinal Materials in North Anhui Province, Suzhou University, Suzhou, Anhui 234000, China.<br /><searchLink fieldCode="AU" term="%22Hu+H%22">Hu H</searchLink>; General Clinical Research Center, Anhui Wanbei Coal-Electricity Group General Hospital, Suzhou, Anhui Province 234000,  China.<br /><searchLink fieldCode="AU" term="%22Zhai+K%22">Zhai K</searchLink>; School of Pharmacy, Wannan Medical University, Wuhu, Anhui 241002, China.; School of Biological and Food Engineering, Engineering Research Center for Development and High Value Utilization of Genuine Medicinal Materials in North Anhui Province, Suzhou University, Suzhou, Anhui 234000, China.
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        Value: 10.1093/jpp/rgag067
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            – D: 02
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              Text: 2026 Jun 02
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