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ALBI Grade is a Determinant of Lenvatinib Pharmacokinetics, Efficacy, and Toxicities in Japanese Patients with Hepatocellular Carcinoma.

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Title: ALBI Grade is a Determinant of Lenvatinib Pharmacokinetics, Efficacy, and Toxicities in Japanese Patients with Hepatocellular Carcinoma.
Authors: Suzuki K; Department of Hospital Pharmaceutics, Showa Medical University School of Pharmacy, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan., Otoyama Y; Division of Gastroenterology, Department of Medicine, Showa Medical University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan., Matsumoto N; Department of Cancer Genome and Pharmacotherapy, Showa Medical University Graduate School of Pharmacy, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan.; Division of Cancer Genome and Pharmacotherapy, Department of Clinical Pharmacy, Showa Medical University School of Pharmacy, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan., Masuo Y; Laboratory of Molecular Pharmacotherapeutics, Faculty of Pharmacy, Kanazawa University, Kakuma-machi, Kanazawa, 920-1192, Japan., Nakajima Y; Division of Gastroenterology, Department of Medicine, Showa Medical University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan., Sugiura I; Division of Gastroenterology, Department of Medicine, Showa Medical University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan., Fuji T; Division of Gastroenterology, Department of Medicine, Showa Medical University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan., Nomura E; Division of Gastroenterology, Department of Medicine, Showa Medical University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan., Ichikawa Y; Division of Gastroenterology, Department of Medicine, Showa Medical University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan., Shimozuma Y; Division of Gastroenterology, Department of Medicine, Showa Medical University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan., Uchikoshi M; Division of Gastroenterology, Department of Medicine, Showa Medical University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan., Hayano M; Division of Cancer Genome and Pharmacotherapy, Department of Clinical Pharmacy, Showa Medical University School of Pharmacy, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan., Hanano M; Division of Cancer Genome and Pharmacotherapy, Department of Clinical Pharmacy, Showa Medical University School of Pharmacy, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan., Murase R; Department of Cancer Genome and Pharmacotherapy, Showa Medical University Graduate School of Pharmacy, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan.; Division of Cancer Genome and Pharmacotherapy, Department of Clinical Pharmacy, Showa Medical University School of Pharmacy, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan., Mitomori C; Laboratory of Molecular Pharmacotherapeutics, Faculty of Pharmacy, Kanazawa University, Kakuma-machi, Kanazawa, 920-1192, Japan., Oka K; Laboratory of Molecular Pharmacotherapeutics, Faculty of Pharmacy, Kanazawa University, Kakuma-machi, Kanazawa, 920-1192, Japan., Sakaki M; Division of Gastroenterology, Department of Medicine, Showa Medical University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan., Kato Y; Laboratory of Molecular Pharmacotherapeutics, Faculty of Pharmacy, Kanazawa University, Kakuma-machi, Kanazawa, 920-1192, Japan., Yoshida H; Division of Gastroenterology, Department of Medicine, Showa Medical University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan., Fujita KI; Department of Cancer Genome and Pharmacotherapy, Showa Medical University Graduate School of Pharmacy, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan. k.fujita@med.showa-u.ac.jp.; Division of Cancer Genome and Pharmacotherapy, Department of Clinical Pharmacy, Showa Medical University School of Pharmacy, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan. k.fujita@med.showa-u.ac.jp.
Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2026 Jun 23. Date of Electronic Publication: 2026 Jun 23.
Publication Type: Journal Article
Journal Info: Publisher: Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1926 (Electronic) Linking ISSN: 03125963 NLM ISO Abbreviation: Clin Pharmacokinet Subsets: MEDLINE
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  Data: ALBI Grade is a Determinant of Lenvatinib Pharmacokinetics, Efficacy, and Toxicities in Japanese Patients with Hepatocellular Carcinoma.
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  Data: <searchLink fieldCode="AU" term="%22Suzuki+K%22">Suzuki K</searchLink>; Department of Hospital Pharmaceutics, Showa Medical University School of Pharmacy, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Otoyama+Y%22">Otoyama Y</searchLink>; Division of Gastroenterology, Department of Medicine, Showa Medical University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Matsumoto+N%22">Matsumoto N</searchLink>; Department of Cancer Genome and Pharmacotherapy, Showa Medical University Graduate School of Pharmacy, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan.; Division of Cancer Genome and Pharmacotherapy, Department of Clinical Pharmacy, Showa Medical University School of Pharmacy, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Masuo+Y%22">Masuo Y</searchLink>; Laboratory of Molecular Pharmacotherapeutics, Faculty of Pharmacy, Kanazawa University, Kakuma-machi, Kanazawa, 920-1192, Japan.<br /><searchLink fieldCode="AU" term="%22Nakajima+Y%22">Nakajima Y</searchLink>; Division of Gastroenterology, Department of Medicine, Showa Medical University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Sugiura+I%22">Sugiura I</searchLink>; Division of Gastroenterology, Department of Medicine, Showa Medical University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Fuji+T%22">Fuji T</searchLink>; Division of Gastroenterology, Department of Medicine, Showa Medical University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Nomura+E%22">Nomura E</searchLink>; Division of Gastroenterology, Department of Medicine, Showa Medical University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Ichikawa+Y%22">Ichikawa Y</searchLink>; Division of Gastroenterology, Department of Medicine, Showa Medical University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Shimozuma+Y%22">Shimozuma Y</searchLink>; Division of Gastroenterology, Department of Medicine, Showa Medical University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Uchikoshi+M%22">Uchikoshi M</searchLink>; Division of Gastroenterology, Department of Medicine, Showa Medical University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Hayano+M%22">Hayano M</searchLink>; Division of Cancer Genome and Pharmacotherapy, Department of Clinical Pharmacy, Showa Medical University School of Pharmacy, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Hanano+M%22">Hanano M</searchLink>; Division of Cancer Genome and Pharmacotherapy, Department of Clinical Pharmacy, Showa Medical University School of Pharmacy, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Murase+R%22">Murase R</searchLink>; Department of Cancer Genome and Pharmacotherapy, Showa Medical University Graduate School of Pharmacy, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan.; Division of Cancer Genome and Pharmacotherapy, Department of Clinical Pharmacy, Showa Medical University School of Pharmacy, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Mitomori+C%22">Mitomori C</searchLink>; Laboratory of Molecular Pharmacotherapeutics, Faculty of Pharmacy, Kanazawa University, Kakuma-machi, Kanazawa, 920-1192, Japan.<br /><searchLink fieldCode="AU" term="%22Oka+K%22">Oka K</searchLink>; Laboratory of Molecular Pharmacotherapeutics, Faculty of Pharmacy, Kanazawa University, Kakuma-machi, Kanazawa, 920-1192, Japan.<br /><searchLink fieldCode="AU" term="%22Sakaki+M%22">Sakaki M</searchLink>; Division of Gastroenterology, Department of Medicine, Showa Medical University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Kato+Y%22">Kato Y</searchLink>; Laboratory of Molecular Pharmacotherapeutics, Faculty of Pharmacy, Kanazawa University, Kakuma-machi, Kanazawa, 920-1192, Japan.<br /><searchLink fieldCode="AU" term="%22Yoshida+H%22">Yoshida H</searchLink>; Division of Gastroenterology, Department of Medicine, Showa Medical University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Fujita+KI%22">Fujita KI</searchLink>; Department of Cancer Genome and Pharmacotherapy, Showa Medical University Graduate School of Pharmacy, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan. k.fujita@med.showa-u.ac.jp.; Division of Cancer Genome and Pharmacotherapy, Department of Clinical Pharmacy, Showa Medical University School of Pharmacy, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan. k.fujita@med.showa-u.ac.jp.
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