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Integrated pan-cancer multi-omics profiling and experimental validation identify LSM12 as a prognostic biomarker and candidate therapeutic target in human cancers.

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Title: Integrated pan-cancer multi-omics profiling and experimental validation identify LSM12 as a prognostic biomarker and candidate therapeutic target in human cancers.
Authors: Eldeen MA; Department of Pathology, College of Korean Medicine, Kyung Hee University, Seoul, 02447, Republic of Korea. dr.muhammadalaa@gmail.com.; ²Division of Computational Genomics and Precision Medicine, EdigenomiX Research Academy, EdigenomiX Scientific Ltd, Zagazig, 44519, Sharqia Governorate, Egypt. dr.muhammadalaa@gmail.com., Refaat AM; Zoology Department, Faculty of Science, Minia University, El-Minia, 61519, Egypt.; Graduate School of Biostudies, Kyoto University, Kyoto, Japan., Ahmed HEM; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Benha University, Benha, Egypt.; Basic Medical Sciences Department, Aqaba Medical Sciences University, Aqaba, Jordan., Hassan HM; 7Department of Pathology, College of Medicine, King Khalid University, Abha, Saudi Arabia., Alshehri M; Department of Child Health, College of Medicine, King Khalid University, Abha, Saudi Arabia., Fayad E; Department of Biotechnology, College of Sciences, Taif University, Taif, 21944, Saudi Arabia., Jafri I; Department of Biotechnology, College of Sciences, Taif University, Taif, 21944, Saudi Arabia., Alshaya DS; Department of Biology, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, 11671, Saudi Arabia., Babteen NA; Department of Biological Sciences, College of Science, University of Jeddah, Jeddah, Saudi Arabia., Sait LM; Biological Sciences Department, College of Science & Arts, King Abdulaziz University, Rabigh, 21911, Saudi Arabia., Alqahtani LS; Department of Biological Sciences, College of Science, University of Jeddah, Jeddah, Saudi Arabia., Kim B; Department of Pathology, College of Korean Medicine, Kyung Hee University, Seoul, 02447, Republic of Korea. bongleekim@khu.ac.kr.; Korean Medicine-Based Drug Repositioning Cancer Research Center, College of Korean Medicine, Kyung Hee University, Seoul, 02447, Republic of Korea. bongleekim@khu.ac.kr.; Samuiwon Startup Center Kyung Hee University, Dr. B Lab Co., Ltd. Room 513, Seoul, 02447, Democratic People's Republic of Korea. bongleekim@khu.ac.kr.; Medical Convergence Research Center, Kyung Hee University Hospital at Gangdong, 23 Kyungheedae-ro, Gangdong-gu, Seoul , 05238, Korea, Republic of (South Korea). bongleekim@khu.ac.kr.
Source: BMC cancer [BMC Cancer] 2026 Jun 23; Vol. 26 (1). Date of Electronic Publication: 2026 Jun 23.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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  Data: Integrated pan-cancer multi-omics profiling and experimental validation identify LSM12 as a prognostic biomarker and candidate therapeutic target in human cancers.
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  Data: <searchLink fieldCode="AU" term="%22Eldeen+MA%22">Eldeen MA</searchLink>; Department of Pathology, College of Korean Medicine, Kyung Hee University, Seoul, 02447, Republic of Korea. dr.muhammadalaa@gmail.com.; ²Division of Computational Genomics and Precision Medicine, EdigenomiX Research Academy, EdigenomiX Scientific Ltd, Zagazig, 44519, Sharqia Governorate, Egypt. dr.muhammadalaa@gmail.com.<br /><searchLink fieldCode="AU" term="%22Refaat+AM%22">Refaat AM</searchLink>; Zoology Department, Faculty of Science, Minia University, El-Minia, 61519, Egypt.; Graduate School of Biostudies, Kyoto University, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Ahmed+HEM%22">Ahmed HEM</searchLink>; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Benha University, Benha, Egypt.; Basic Medical Sciences Department, Aqaba Medical Sciences University, Aqaba, Jordan.<br /><searchLink fieldCode="AU" term="%22Hassan+HM%22">Hassan HM</searchLink>; 7Department of Pathology, College of Medicine, King Khalid University, Abha, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alshehri+M%22">Alshehri M</searchLink>; Department of Child Health, College of Medicine, King Khalid University, Abha, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Fayad+E%22">Fayad E</searchLink>; Department of Biotechnology, College of Sciences, Taif University, Taif, 21944, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Jafri+I%22">Jafri I</searchLink>; Department of Biotechnology, College of Sciences, Taif University, Taif, 21944, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alshaya+DS%22">Alshaya DS</searchLink>; Department of Biology, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, 11671, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Babteen+NA%22">Babteen NA</searchLink>; Department of Biological Sciences, College of Science, University of Jeddah, Jeddah, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Sait+LM%22">Sait LM</searchLink>; Biological Sciences Department, College of Science & Arts, King Abdulaziz University, Rabigh, 21911, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alqahtani+LS%22">Alqahtani LS</searchLink>; Department of Biological Sciences, College of Science, University of Jeddah, Jeddah, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Kim+B%22">Kim B</searchLink>; Department of Pathology, College of Korean Medicine, Kyung Hee University, Seoul, 02447, Republic of Korea. bongleekim@khu.ac.kr.; Korean Medicine-Based Drug Repositioning Cancer Research Center, College of Korean Medicine, Kyung Hee University, Seoul, 02447, Republic of Korea. bongleekim@khu.ac.kr.; Samuiwon Startup Center Kyung Hee University, Dr. B Lab Co., Ltd. Room 513, Seoul, 02447, Democratic People's Republic of Korea. bongleekim@khu.ac.kr.; Medical Convergence Research Center, Kyung Hee University Hospital at Gangdong, 23 Kyungheedae-ro, Gangdong-gu, Seoul , 05238, Korea, Republic of (South Korea). bongleekim@khu.ac.kr.
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  Data: <searchLink fieldCode="JN" term="%22100967800%22">BMC cancer</searchLink> [BMC Cancer] 2026 Jun 23; Vol. 26 (1). <i>Date of Electronic Publication: </i>2026 Jun 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100967800 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1471-2407 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214712407%22">14712407 </searchLink><i>NLM ISO Abbreviation: </i>BMC Cancer <i>Subsets: </i>MEDLINE; In Process
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              Text: 2026 Jun 23
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