Bortezomib-induced gastrointestinal dysfunction, peripheral neuropathy and neuroimmune signalling are influenced by the gut microbiota in mice.
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| Title: | Bortezomib-induced gastrointestinal dysfunction, peripheral neuropathy and neuroimmune signalling are influenced by the gut microbiota in mice. |
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| Authors: | Scott JS; Supportive Oncology Research Group, School of Pharmacy and Biomedical Science, College of Health, Adelaide University, Adelaide, SA, Australia.; Precision Cancer Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA, Australia., Munir S; Precision Cancer Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA, Australia.; Myeloma Research Laboratory, School of Pharmacy and Biomedical Science, College of Health, Adelaide University, Adelaide, SA, Australia., Lynn MA; Precision Cancer Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA, Australia.; Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA, Australia., Duggan JA; Precision Cancer Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA, Australia.; Myeloma Research Laboratory, School of Pharmacy and Biomedical Science, College of Health, Adelaide University, Adelaide, SA, Australia., Castro J; Visceral Pain Research Group, Hopwood Centre for Neurobiology, South Australian Health and Medical Research Institute, Adelaide, SA, Australia.; College of Health, Adelaide University, Adelaide, SA, Australia., Harrington AM; Visceral Pain Research Group, Hopwood Centre for Neurobiology, South Australian Health and Medical Research Institute, Adelaide, SA, Australia.; College of Health, Adelaide University, Adelaide, SA, Australia., Brierley SM; Visceral Pain Research Group, Hopwood Centre for Neurobiology, South Australian Health and Medical Research Institute, Adelaide, SA, Australia.; College of Health, Adelaide University, Adelaide, SA, Australia., Schober G; Visceral Pain Research Group, Hopwood Centre for Neurobiology, South Australian Health and Medical Research Institute, Adelaide, SA, Australia., Cash K; Muscle and Nerve Laboratory, Directorate of Anatomical Pathology, SA Pathology, Adelaide, SA, Australia., Gutschmidt B; Muscle and Nerve Laboratory, Directorate of Anatomical Pathology, SA Pathology, Adelaide, SA, Australia., Hutchinson MR; College of Health, Adelaide University, Adelaide, SA, Australia.; Institute for Photonics and Advanced Sensing, Adelaide University, Adelaide, SA, Australia., Yong A; College of Health, Adelaide University, Adelaide, SA, Australia.; Department of Haematology, Royal Adelaide Hospital, SA Health, Adelaide, SA, Australia., Costello SP; College of Health, Adelaide University, Adelaide, SA, Australia.; Gastroenterology Department, The Queen Elizabeth Hospital, Woodville South, SA, Australia., Sikdar S; Supportive Oncology Research Group, School of Pharmacy and Biomedical Science, College of Health, Adelaide University, Adelaide, SA, Australia.; Precision Cancer Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA, Australia., Tangseefa P; Precision Cancer Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA, Australia.; Myeloma Research Laboratory, School of Pharmacy and Biomedical Science, College of Health, Adelaide University, Adelaide, SA, Australia., Hewett DR; Precision Cancer Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA, Australia.; Myeloma Research Laboratory, School of Pharmacy and Biomedical Science, College of Health, Adelaide University, Adelaide, SA, Australia., Cross CB; Supportive Oncology Research Group, School of Pharmacy and Biomedical Science, College of Health, Adelaide University, Adelaide, SA, Australia.; Precision Cancer Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA, Australia., Park SB; School of Medical Sciences, Faculty of Medicine and Health, and Brain and Mind Centre, University of Sydney, Sydney, NSW, Australia., Ryan FJ; Precision Cancer Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA, Australia.; Computational Multi-Omics Group, Flinders Health and Medical Research Institute, College of Medicine and Public Health, Flinders University, Bedford Park, SA, Australia., Zannettino ACW; Precision Cancer Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA, Australia.; Myeloma Research Laboratory, School of Pharmacy and Biomedical Science, College of Health, Adelaide University, Adelaide, SA, Australia., Lynn DJ; Precision Cancer Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA, Australia.; Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA, Australia., Vandyke K; Precision Cancer Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA, Australia.; Myeloma Research Laboratory, School of Pharmacy and Biomedical Science, College of Health, Adelaide University, Adelaide, SA, Australia., Wardill HR; Supportive Oncology Research Group, School of Pharmacy and Biomedical Science, College of Health, Adelaide University, Adelaide, SA, Australia. hannah.wardill@adelaide.edu.au.; Precision Cancer Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA, Australia. hannah.wardill@adelaide.edu.au., Mrozik KM; Precision Cancer Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA, Australia. krzysztof.mrozik@adelaide.edu.au.; Myeloma Research Laboratory, School of Pharmacy and Biomedical Science, College of Health, Adelaide University, Adelaide, SA, Australia. krzysztof.mrozik@adelaide.edu.au. |
| Source: | Journal of neuroinflammation [J Neuroinflammation] 2026 Jun 23. Date of Electronic Publication: 2026 Jun 23. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-2094 (Electronic) Linking ISSN: 17422094 NLM ISO Abbreviation: J Neuroinflammation Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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