Ruxolitinib Pharmacokinetics and Exposure-Toxicity Relationship in Hematologic Malignancies and Immune-Mediated Diseases: A Prospective Observational Study.
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| Title: | Ruxolitinib Pharmacokinetics and Exposure-Toxicity Relationship in Hematologic Malignancies and Immune-Mediated Diseases: A Prospective Observational Study. |
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| Authors: | Tachet J; Service of Clinical Pharmacology, Department of Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Meyer SC; Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland., Grandoni F; Service and Central Laboratory of Hematology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Haefliger E; Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland., Nagy-Hulliger M; Service of Hematology, Hospital of Morges, Morges, Switzerland., Halter JP; Division of Hematology, Basel University Hospital and University of Basel, Basel, Switzerland., Passweg JR; Division of Hematology, Basel University Hospital and University of Basel, Basel, Switzerland., Haefliger D; Service of Clinical Pharmacology, Department of Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Bardinet C; Laboratory of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Decosterd LA; Laboratory of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Guidi M; Service of Clinical Pharmacology, Department of Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Center for Research and Innovation in Clinical Pharmaceutical Sciences, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, University of Lausanne, Geneva, Lausanne, Switzerland., Girardin FR; Service of Clinical Pharmacology, Department of Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Laboratory of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland. |
| Source: | Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2026 Jun 24. Date of Electronic Publication: 2026 Jun 24. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42338396 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Ruxolitinib Pharmacokinetics and Exposure-Toxicity Relationship in Hematologic Malignancies and Immune-Mediated Diseases: A Prospective Observational Study. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Tachet+J%22">Tachet J</searchLink>; Service of Clinical Pharmacology, Department of Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Meyer+SC%22">Meyer SC</searchLink>; Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Grandoni+F%22">Grandoni F</searchLink>; Service and Central Laboratory of Hematology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Haefliger+E%22">Haefliger E</searchLink>; Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Nagy-Hulliger+M%22">Nagy-Hulliger M</searchLink>; Service of Hematology, Hospital of Morges, Morges, Switzerland.<br /><searchLink fieldCode="AU" term="%22Halter+JP%22">Halter JP</searchLink>; Division of Hematology, Basel University Hospital and University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Passweg+JR%22">Passweg JR</searchLink>; Division of Hematology, Basel University Hospital and University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Haefliger+D%22">Haefliger D</searchLink>; Service of Clinical Pharmacology, Department of Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bardinet+C%22">Bardinet C</searchLink>; Laboratory of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Decosterd+LA%22">Decosterd LA</searchLink>; Laboratory of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Guidi+M%22">Guidi M</searchLink>; Service of Clinical Pharmacology, Department of Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Center for Research and Innovation in Clinical Pharmaceutical Sciences, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, University of Lausanne, Geneva, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Girardin+FR%22">Girardin FR</searchLink>; Service of Clinical Pharmacology, Department of Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Laboratory of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220372741%22">Clinical pharmacology and therapeutics</searchLink> [Clin Pharmacol Ther] 2026 Jun 24. <i>Date of Electronic Publication: </i>2026 Jun 24. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley%22">Wiley </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0372741 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1532-6535 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200099236%22">00099236 </searchLink><i>NLM ISO Abbreviation: </i>Clin Pharmacol Ther <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42338396 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/cpt.70367 Languages: – Code: eng Text: English Titles: – TitleFull: Ruxolitinib Pharmacokinetics and Exposure-Toxicity Relationship in Hematologic Malignancies and Immune-Mediated Diseases: A Prospective Observational Study. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Tachet J – PersonEntity: Name: NameFull: Meyer SC – PersonEntity: Name: NameFull: Grandoni F – PersonEntity: Name: NameFull: Haefliger E – PersonEntity: Name: NameFull: Nagy-Hulliger M – PersonEntity: Name: NameFull: Halter JP – PersonEntity: Name: NameFull: Passweg JR – PersonEntity: Name: NameFull: Haefliger D – PersonEntity: Name: NameFull: Bardinet C – PersonEntity: Name: NameFull: Decosterd LA – PersonEntity: Name: NameFull: Guidi M – PersonEntity: Name: NameFull: Girardin FR IsPartOfRelationships: – BibEntity: Dates: – D: 24 M: 06 Text: 2026 Jun 24 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1532-6535 Titles: – TitleFull: Clinical pharmacology and therapeutics Type: main |
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