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Spatial and multi-omic profiling reveals pericyte-derived CCL19 as a key prognostic factor in CNS lymphoma.

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Title: Spatial and multi-omic profiling reveals pericyte-derived CCL19 as a key prognostic factor in CNS lymphoma.
Authors: Kuehn JC; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine University of Freiburg Freiburg Germany., Miarka L; Institute of Neuropathology, Faculty of Medicine University of Freiburg Freiburg Germany., Sankowski R; Institute of Neuropathology, Faculty of Medicine University of Freiburg Freiburg Germany.; German Cancer Consortium (DKTK) Partner Site Freiburg and German Cancer Research Center (DKFZ) Heidelberg Germany., Mutter J; Department of Medicine, Divisions of Oncology and Hematology Stanford University Stanford California USA., Neidert NN; German Cancer Consortium (DKTK) Partner Site Freiburg and German Cancer Research Center (DKFZ) Heidelberg Germany.; Department of Neurosurgery, Medical Center - University of Freiburg, Faculty of Medicine University of Freiburg Freiburg Germany., Grabis E; Department of Neurosurgery, Medical Center - University of Freiburg, Faculty of Medicine University of Freiburg Freiburg Germany., Zhang J; Department of Neurosurgery, Medical Center - University of Freiburg, Faculty of Medicine University of Freiburg Freiburg Germany., Klingler C; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine University of Freiburg Freiburg Germany., Hummel F; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine University of Freiburg Freiburg Germany., Ranganathan L; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine University of Freiburg Freiburg Germany., Bleul S; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine University of Freiburg Freiburg Germany., Lauer EM; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine University of Freiburg Freiburg Germany., Heiland DH; German Cancer Consortium (DKTK) Partner Site Freiburg and German Cancer Research Center (DKFZ) Heidelberg Germany.; Department of Neurosurgery, Medical Center - University of Freiburg, Faculty of Medicine University of Freiburg Freiburg Germany.; Department of Neurosurgery, University Hospital Erlangen Friedrich-Alexander University Erlangen-Nürnberg Erlangen Germany.; Department of Neurological Surgery, Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine Northwestern University Chicago Illinois USA., Müller K; Department of Neurology, University Hospital LMU Munich Munich Germany., Reinhardt HC; Department of Hematology and Stem Cell Transplantation University Hospital Essen, University Duisburg-Essen, West German Cancer Center, German Cancer Consortium (DKTK Partner Site Essen), Center for Molecular Biotechnology Essen Germany., Dietrich S; Department of Hematology, Oncology and Clinical Immunology University Hospital Düsseldorf Düsseldorf Germany., Illerhaus G; Clinic of Hematology, Oncology, Stem Cell Transplantation and Palliative Care, Klinikum Stuttgart Stuttgart Germany., von Baumgarten L; Department of Neurology, University Hospital LMU Munich Munich Germany., Alig S; Department of Hematology and Stem Cell Transplantation University Hospital Essen, University Duisburg-Essen, West German Cancer Center, German Cancer Consortium (DKTK Partner Site Essen), Center for Molecular Biotechnology Essen Germany., Diehn M; Department of Radiation Oncology Stanford University Medical Center Stanford California USA., Sajonz BEA; Department of Stereotactic and Functional Neurosurgery, Medical Center - University of Freiburg, Faculty of Medicine University of Freiburg Freiburg Germany., Beck J; Department of Neurosurgery, Medical Center - University of Freiburg, Faculty of Medicine University of Freiburg Freiburg Germany., Coenen VA; Department of Stereotactic and Functional Neurosurgery, Medical Center - University of Freiburg, Faculty of Medicine University of Freiburg Freiburg Germany., Prinz M; Institute of Neuropathology, Faculty of Medicine University of Freiburg Freiburg Germany.; Signalling Research Centres BIOSS and CIBSS University of Freiburg Freiburg Germany., Schorb E; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine University of Freiburg Freiburg Germany., Alizadeh AA; Department of Medicine, Divisions of Oncology and Hematology Stanford University Stanford California USA., Duyster J; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine University of Freiburg Freiburg Germany., Reinacher P; Department of Stereotactic and Functional Neurosurgery, Medical Center - University of Freiburg, Faculty of Medicine University of Freiburg Freiburg Germany.; Fraunhofer Institute for Laser Technology (ILT) Aachen Germany., Scherer F; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine University of Freiburg Freiburg Germany.; German Cancer Consortium (DKTK) Partner Site Freiburg and German Cancer Research Center (DKFZ) Heidelberg Germany.
Source: HemaSphere [Hemasphere] 2026 Jun 22; Vol. 10 (6), pp. e70412. Date of Electronic Publication: 2026 Jun 22 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101740619 Publication Model: eCollection Cited Medium: Internet ISSN: 2572-9241 (Electronic) Linking ISSN: 25729241 NLM ISO Abbreviation: Hemasphere Subsets: PubMed not MEDLINE
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