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A secretion-deficient DENV1 DNA vaccine induces durable immunity and confers protection against DENV2.

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Title: A secretion-deficient DENV1 DNA vaccine induces durable immunity and confers protection against DENV2.
Authors: Zhang C; Department of Microbiology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China.; Laboratory for Clinical Medicine, Capital Medical University, Beijing 100069, China., Feng KH; Graduate School, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100005, China., Liu YX; Department of Microbiology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China.; Laboratory for Clinical Medicine, Capital Medical University, Beijing 100069, China., Zhong CY; Department of Microbiology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China.; Laboratory for Clinical Medicine, Capital Medical University, Beijing 100069, China., Lin KQ; Department of Microbiology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China.; Laboratory for Clinical Medicine, Capital Medical University, Beijing 100069, China., Chen H; Department of Microbiology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China., Fan DY; Department of Microbiology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China.; Laboratory for Clinical Medicine, Capital Medical University, Beijing 100069, China., An J; Department of Microbiology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China.; Laboratory for Clinical Medicine, Capital Medical University, Beijing 100069, China. E-mail: anjing@ccmu.edu.cn., Wang PG; Department of Microbiology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China.; Laboratory for Clinical Medicine, Capital Medical University, Beijing 100069, China. E-mail: pgwang@ccmu.edu.cn., Gao N; Department of Microbiology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China.; Laboratory for Clinical Medicine, Capital Medical University, Beijing 100069, China. E-mail: gao_na@ccmu.edu.cn.
Source: Zoological research [Zool Res] 2026 May 18; Vol. 47 (3), pp. 988-1002.
Publication Type: Journal Article
Journal Info: Publisher: Science Press Country of Publication: China NLM ID: 101697192 Publication Model: Print Cited Medium: Internet ISSN: 2095-8137 (Print) Linking ISSN: 20958137 NLM ISO Abbreviation: Zool Res Subsets: MEDLINE; In Process
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  Data: <searchLink fieldCode="AU" term="%22Zhang+C%22">Zhang C</searchLink>; Department of Microbiology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China.; Laboratory for Clinical Medicine, Capital Medical University, Beijing 100069, China.<br /><searchLink fieldCode="AU" term="%22Feng+KH%22">Feng KH</searchLink>; Graduate School, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100005, China.<br /><searchLink fieldCode="AU" term="%22Liu+YX%22">Liu YX</searchLink>; Department of Microbiology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China.; Laboratory for Clinical Medicine, Capital Medical University, Beijing 100069, China.<br /><searchLink fieldCode="AU" term="%22Zhong+CY%22">Zhong CY</searchLink>; Department of Microbiology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China.; Laboratory for Clinical Medicine, Capital Medical University, Beijing 100069, China.<br /><searchLink fieldCode="AU" term="%22Lin+KQ%22">Lin KQ</searchLink>; Department of Microbiology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China.; Laboratory for Clinical Medicine, Capital Medical University, Beijing 100069, China.<br /><searchLink fieldCode="AU" term="%22Chen+H%22">Chen H</searchLink>; Department of Microbiology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China.<br /><searchLink fieldCode="AU" term="%22Fan+DY%22">Fan DY</searchLink>; Department of Microbiology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China.; Laboratory for Clinical Medicine, Capital Medical University, Beijing 100069, China.<br /><searchLink fieldCode="AU" term="%22An+J%22">An J</searchLink>; Department of Microbiology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China.; Laboratory for Clinical Medicine, Capital Medical University, Beijing 100069, China. E-mail: anjing@ccmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Wang+PG%22">Wang PG</searchLink>; Department of Microbiology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China.; Laboratory for Clinical Medicine, Capital Medical University, Beijing 100069, China. E-mail: pgwang@ccmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Gao+N%22">Gao N</searchLink>; Department of Microbiology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China.; Laboratory for Clinical Medicine, Capital Medical University, Beijing 100069, China. E-mail: gao_na@ccmu.edu.cn.
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              Text: 2026 May 18
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