Impact of preexisting interstitial lung disease on pneumonitis and survival during first-line immune checkpoint inhibitor-based therapy in non-small cell lung cancer.

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Title: Impact of preexisting interstitial lung disease on pneumonitis and survival during first-line immune checkpoint inhibitor-based therapy in non-small cell lung cancer.
Authors: Matsumoto K; Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, the University of Osaka, Osaka, Japan., Yamamoto Y; Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, the University of Osaka, Osaka, Japan., Shiroyama T; Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, the University of Osaka, Osaka, Japan. Electronic address: takayuki.s12@hotmail.co.jp., Kuge T; Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, the University of Osaka, Osaka, Japan; Department of Thoracic Oncology, NHO Osaka Toneyama Medical Center, Osaka, Japan., Miyazaki A; Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka, Japan., Komuta K; Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka, Japan., Tamiya M; Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka, Japan., Nishino K; Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka, Japan., Tsukaguchi A; Department of Internal Medicine, NHO Kinki Chuo Chest Medical Center, Osaka, Japan., Tamiya A; Department of Internal Medicine, NHO Kinki Chuo Chest Medical Center, Osaka, Japan., Mihashi Y; Department of Thoracic Oncology, NHO Osaka Toneyama Medical Center, Osaka, Japan., Uchida J; Department of Thoracic Oncology, NHO Osaka Toneyama Medical Center, Osaka, Japan., Mori M; Department of Thoracic Oncology, NHO Osaka Toneyama Medical Center, Osaka, Japan., Yamauchi K; Department of Thoracic Oncology, Osaka Habikino Medical Center, Osaka, Japan., Suzuki H; Department of Thoracic Oncology, Osaka Habikino Medical Center, Osaka, Japan., Kinehara Y; Department of Respiratory Medicine and Clinical Immunology, Nippon Life Hospital, Osaka, Japan., Moritomo K; Department of Respiratory Medicine, Osaka Keisatsu Hospital, Osaka, Japan., Shoshihara N; Department of Respiratory Medicine, Osaka Keisatsu Hospital, Osaka, Japan., Machiyama H; Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, the University of Osaka, Osaka, Japan., Kanaoka K; Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, the University of Osaka, Osaka, Japan., Tobita S; Department of Respiratory Medicine, Osaka General Medical Center, Osaka, Japan., Ueno K; Department of Respiratory Medicine, Osaka General Medical Center, Osaka, Japan., Niki T; Department of Respiratory Medicine, Nishinomiya Municipal Central Hospital, Hyogo, Japan., Tetsumoto S; Department of Respiratory Medicine and Clinical Immunology, Suita Municipal Hospital, Osaka, Japan., Nishikawa Y; Department of Respiratory Medicine, Toyonaka Municipal Hospital, Osaka, Japan., Morimura O; Department of Respiratory Medicine, Toyonaka Municipal Hospital, Osaka, Japan., Kato S; Department of Respiratory Medicine, Ikeda City Hospital, Osaka, Japan., Yoneda M; Department of Respiratory Medicine, Ikeda City Hospital, Osaka, Japan., Azuma K; Department of Respiratory Medicine, NHO Osaka National Hospital, Osaka, Japan., Osa A; Department of Respiratory Medicine, Kinki Central Hospital, Hyogo, Japan., Minami T; Department of Respiratory Medicine and Hematology, Hyogo Medical University, Hyogo, Japan., Nagatomo I; Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, the University of Osaka, Osaka, Japan., Takeda Y; Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, the University of Osaka, Osaka, Japan., Kumanogoh A; Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, the University of Osaka, Osaka, Japan; Department of Immunopathology, World Premier International (WPI), Immunology Frontier Research Center (iFReC), the University of Osaka, Osaka, Japan; Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives (OTRI), the University of Osaka, Osaka, Japan; Center for Infectious Diseases for Education and Research (CiDER), the University of Osaka, Suita, Osaka, Japan; Japan Agency for Medical Research and Development - Core Research for Evolutional Science and Technology (AMED-CREST), the University of Osaka, Osaka, Japan; Center for Advanced Modalities and DDS (CAMaD), the University of Osaka, Osaka, Japan.
Source: European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2026 Jun 21; Vol. 244, pp. 116902. Date of Electronic Publication: 2026 Jun 21.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9005373 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0852 (Electronic) Linking ISSN: 09598049 NLM ISO Abbreviation: Eur J Cancer Subsets: MEDLINE
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  Data: Impact of preexisting interstitial lung disease on pneumonitis and survival during first-line immune checkpoint inhibitor-based therapy in non-small cell lung cancer.
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  Data: <searchLink fieldCode="AU" term="%22Matsumoto+K%22">Matsumoto K</searchLink>; Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, the University of Osaka, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Yamamoto+Y%22">Yamamoto Y</searchLink>; Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, the University of Osaka, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Shiroyama+T%22">Shiroyama T</searchLink>; Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, the University of Osaka, Osaka, Japan. Electronic address: takayuki.s12@hotmail.co.jp.<br /><searchLink fieldCode="AU" term="%22Kuge+T%22">Kuge T</searchLink>; Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, the University of Osaka, Osaka, Japan; Department of Thoracic Oncology, NHO Osaka Toneyama Medical Center, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Miyazaki+A%22">Miyazaki A</searchLink>; Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Komuta+K%22">Komuta K</searchLink>; Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Tamiya+M%22">Tamiya M</searchLink>; Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Nishino+K%22">Nishino K</searchLink>; Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Tsukaguchi+A%22">Tsukaguchi A</searchLink>; Department of Internal Medicine, NHO Kinki Chuo Chest Medical Center, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Tamiya+A%22">Tamiya A</searchLink>; Department of Internal Medicine, NHO Kinki Chuo Chest Medical Center, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Mihashi+Y%22">Mihashi Y</searchLink>; Department of Thoracic Oncology, NHO Osaka Toneyama Medical Center, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Uchida+J%22">Uchida J</searchLink>; Department of Thoracic Oncology, NHO Osaka Toneyama Medical Center, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Mori+M%22">Mori M</searchLink>; Department of Thoracic Oncology, NHO Osaka Toneyama Medical Center, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Yamauchi+K%22">Yamauchi K</searchLink>; Department of Thoracic Oncology, Osaka Habikino Medical Center, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Suzuki+H%22">Suzuki H</searchLink>; Department of Thoracic Oncology, Osaka Habikino Medical Center, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Kinehara+Y%22">Kinehara Y</searchLink>; Department of Respiratory Medicine and Clinical Immunology, Nippon Life Hospital, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Moritomo+K%22">Moritomo K</searchLink>; Department of Respiratory Medicine, Osaka Keisatsu Hospital, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Shoshihara+N%22">Shoshihara N</searchLink>; Department of Respiratory Medicine, Osaka Keisatsu Hospital, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Machiyama+H%22">Machiyama H</searchLink>; Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, the University of Osaka, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Kanaoka+K%22">Kanaoka K</searchLink>; Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, the University of Osaka, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Tobita+S%22">Tobita S</searchLink>; Department of Respiratory Medicine, Osaka General Medical Center, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Ueno+K%22">Ueno K</searchLink>; Department of Respiratory Medicine, Osaka General Medical Center, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Niki+T%22">Niki T</searchLink>; Department of Respiratory Medicine, Nishinomiya Municipal Central Hospital, Hyogo, Japan.<br /><searchLink fieldCode="AU" term="%22Tetsumoto+S%22">Tetsumoto S</searchLink>; Department of Respiratory Medicine and Clinical Immunology, Suita Municipal Hospital, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Nishikawa+Y%22">Nishikawa Y</searchLink>; Department of Respiratory Medicine, Toyonaka Municipal Hospital, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Morimura+O%22">Morimura O</searchLink>; Department of Respiratory Medicine, Toyonaka Municipal Hospital, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Kato+S%22">Kato S</searchLink>; Department of Respiratory Medicine, Ikeda City Hospital, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Yoneda+M%22">Yoneda M</searchLink>; Department of Respiratory Medicine, Ikeda City Hospital, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Azuma+K%22">Azuma K</searchLink>; Department of Respiratory Medicine, NHO Osaka National Hospital, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Osa+A%22">Osa A</searchLink>; Department of Respiratory Medicine, Kinki Central Hospital, Hyogo, Japan.<br /><searchLink fieldCode="AU" term="%22Minami+T%22">Minami T</searchLink>; Department of Respiratory Medicine and Hematology, Hyogo Medical University, Hyogo, Japan.<br /><searchLink fieldCode="AU" term="%22Nagatomo+I%22">Nagatomo I</searchLink>; Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, the University of Osaka, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Takeda+Y%22">Takeda Y</searchLink>; Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, the University of Osaka, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Kumanogoh+A%22">Kumanogoh A</searchLink>; Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, the University of Osaka, Osaka, Japan; Department of Immunopathology, World Premier International (WPI), Immunology Frontier Research Center (iFReC), the University of Osaka, Osaka, Japan; Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives (OTRI), the University of Osaka, Osaka, Japan; Center for Infectious Diseases for Education and Research (CiDER), the University of Osaka, Suita, Osaka, Japan; Japan Agency for Medical Research and Development - Core Research for Evolutional Science and Technology (AMED-CREST), the University of Osaka, Osaka, Japan; Center for Advanced Modalities and DDS (CAMaD), the University of Osaka, Osaka, Japan.
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  Data: <searchLink fieldCode="JN" term="%229005373%22">European journal of cancer (Oxford, England : 1990)</searchLink> [Eur J Cancer] 2026 Jun 21; Vol. 244, pp. 116902. <i>Date of Electronic Publication: </i>2026 Jun 21.
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