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Metabolism of the antioxidant micronutrient ergothioneine as a plasma biomarker of cognitive resilience in older people with Alzheimer's disease amyloid pathology.

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Title: Metabolism of the antioxidant micronutrient ergothioneine as a plasma biomarker of cognitive resilience in older people with Alzheimer's disease amyloid pathology.
Authors: Chong JR; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117599, Singapore; Memory Aging and Cognition Centre, National University Health System, Singapore, 117597, Singapore., Cheah IK; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117596, Singapore; Life Science Institute, Neurobiology Programme, Centre for Life Sciences, National University of Singapore, Singapore, 117456, Singapore., Tang RM; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117596, Singapore; Life Science Institute, Neurobiology Programme, Centre for Life Sciences, National University of Singapore, Singapore, 117456, Singapore., Halliwell B; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117596, Singapore; Life Science Institute, Neurobiology Programme, Centre for Life Sciences, National University of Singapore, Singapore, 117456, Singapore., Chen CP; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117599, Singapore; Memory Aging and Cognition Centre, National University Health System, Singapore, 117597, Singapore., Lai MKP; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117599, Singapore; Memory Aging and Cognition Centre, National University Health System, Singapore, 117597, Singapore. Electronic address: mitchell.lai@dementia-research.org.
Source: Free radical biology & medicine [Free Radic Biol Med] 2026 Jun 25; Vol. 254, pp. 370-377. Date of Electronic Publication: 2026 Jun 25.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Chong+JR%22">Chong JR</searchLink>; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117599, Singapore; Memory Aging and Cognition Centre, National University Health System, Singapore, 117597, Singapore.<br /><searchLink fieldCode="AU" term="%22Cheah+IK%22">Cheah IK</searchLink>; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117596, Singapore; Life Science Institute, Neurobiology Programme, Centre for Life Sciences, National University of Singapore, Singapore, 117456, Singapore.<br /><searchLink fieldCode="AU" term="%22Tang+RM%22">Tang RM</searchLink>; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117596, Singapore; Life Science Institute, Neurobiology Programme, Centre for Life Sciences, National University of Singapore, Singapore, 117456, Singapore.<br /><searchLink fieldCode="AU" term="%22Halliwell+B%22">Halliwell B</searchLink>; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117596, Singapore; Life Science Institute, Neurobiology Programme, Centre for Life Sciences, National University of Singapore, Singapore, 117456, Singapore.<br /><searchLink fieldCode="AU" term="%22Chen+CP%22">Chen CP</searchLink>; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117599, Singapore; Memory Aging and Cognition Centre, National University Health System, Singapore, 117597, Singapore.<br /><searchLink fieldCode="AU" term="%22Lai+MKP%22">Lai MKP</searchLink>; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117599, Singapore; Memory Aging and Cognition Centre, National University Health System, Singapore, 117597, Singapore. Electronic address: mitchell.lai@dementia-research.org.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8709159 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-4596 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208915849%22">08915849 </searchLink><i>NLM ISO Abbreviation: </i>Free Radic Biol Med <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.freeradbiomed.2026.06.043
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      – TitleFull: Metabolism of the antioxidant micronutrient ergothioneine as a plasma biomarker of cognitive resilience in older people with Alzheimer's disease amyloid pathology.
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              Text: 2026 Jun 25
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