Single-Cell Transcriptomic and Metabolic Signatures in Exhausted and Classical Memory B Cells-An Exploratory Analysis in Systemic Lupus Erythematosus and Lupus Nephritis.

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Title: Single-Cell Transcriptomic and Metabolic Signatures in Exhausted and Classical Memory B Cells-An Exploratory Analysis in Systemic Lupus Erythematosus and Lupus Nephritis.
Authors: Zhu L; Division of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.; National Clinical Research Center for Kidney Disease, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.; State Key Laboratory of Multi-Organ Injury Prevention and Treatment, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.; Guangdong Provincial Institute of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.; Guangdong Provincial Key Laboratory of Renal Failure Research, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China., Lin T; Clinical Pharmacy Center, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.; Cancer Research Institute, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China., Cheong LY; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China., Sher JKH; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China., Yam IYL; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China., Cheung W; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China., Yung S; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China., Chan TM; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China., Yap DYH; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China.
Source: Biomedicines [Biomedicines] 2026 May 25; Vol. 14 (6). Date of Electronic Publication: 2026 May 25.
Publication Type: Journal Article
Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101691304 Publication Model: Electronic Cited Medium: Print ISSN: 2227-9059 (Print) Linking ISSN: 22279059 NLM ISO Abbreviation: Biomedicines Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Single-Cell Transcriptomic and Metabolic Signatures in Exhausted and Classical Memory B Cells-An Exploratory Analysis in Systemic Lupus Erythematosus and Lupus Nephritis.
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  Data: <searchLink fieldCode="AU" term="%22Zhu+L%22">Zhu L</searchLink>; Division of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.; National Clinical Research Center for Kidney Disease, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.; State Key Laboratory of Multi-Organ Injury Prevention and Treatment, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.; Guangdong Provincial Institute of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.; Guangdong Provincial Key Laboratory of Renal Failure Research, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Lin+T%22">Lin T</searchLink>; Clinical Pharmacy Center, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.; Cancer Research Institute, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.<br /><searchLink fieldCode="AU" term="%22Cheong+LY%22">Cheong LY</searchLink>; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Sher+JKH%22">Sher JKH</searchLink>; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Yam+IYL%22">Yam IYL</searchLink>; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Cheung+W%22">Cheung W</searchLink>; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Yung+S%22">Yung S</searchLink>; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Chan+TM%22">Chan TM</searchLink>; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Yap+DYH%22">Yap DYH</searchLink>; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China.
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  Data: <searchLink fieldCode="JN" term="%22101691304%22">Biomedicines</searchLink> [Biomedicines] 2026 May 25; Vol. 14 (6). <i>Date of Electronic Publication: </i>2026 May 25.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22MDPI+AG%22">MDPI AG </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101691304 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2227-9059 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2222279059%22">22279059 </searchLink><i>NLM ISO Abbreviation: </i>Biomedicines <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.3390/biomedicines14061188
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      – TitleFull: Single-Cell Transcriptomic and Metabolic Signatures in Exhausted and Classical Memory B Cells-An Exploratory Analysis in Systemic Lupus Erythematosus and Lupus Nephritis.
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            – D: 25
              M: 05
              Text: 2026 May 25
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