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Trisomy 8 clonal expansion during disease progression and azacitidine resistance in VEXAS syndrome: a case report.

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Title: Trisomy 8 clonal expansion during disease progression and azacitidine resistance in VEXAS syndrome: a case report.
Authors: Sato K; Department of Hematology, Japanese Red Cross Nagano Hospital, Nagano, Japan., Zaimoku Y; Department of Hematology, Kanazawa University Hospital, Kanazawa, Japan.; Innovate Clinical Research Center, Kanazawa University Hospital, Kanazawa, Japan., Kano Y; Department of Clinical Laboratory Science, Division of Health Sciences, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan., Kobayashi M; Department of Clinical Laboratory Science, Division of Health Sciences, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan., Kazama S; Department of Hematology, Japanese Red Cross Nagano Hospital, Nagano, Japan., Morikawa T; Department of Hematology, Japanese Red Cross Nagano Hospital, Nagano, Japan., Kazumoto H; Department of Hematology, Japanese Red Cross Nagano Hospital, Nagano, Japan., Ishii W; Department of Rheumatology, Japanese Red Cross Nagano Hospital, Nagano, Japan., Ueki T; Department of Hematology, Japanese Red Cross Nagano Hospital, Nagano, Japan., Sumi M; Department of Hematology, Japanese Red Cross Nagano Hospital, Nagano, Japan., Kobayashi H; Department of Hematology, Japanese Red Cross Nagano Hospital, Nagano, Japan., Nannya Y; Division of Hematopoietic Disease Control, Institute of Medical Science, The University of Tokyo, Tokyo, Japan., Ogawa S; Department of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan.; Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto, Japan.; Department of Innovative Medicine, Faculty of Medicine, Kindai University, Osakasayama, Japan., Ichikawa N; Department of Medical Oncology, Japanese Red Cross Nagano Hospital, Nagano, Japan.
Source: Frontiers in immunology [Front Immunol] 2026 Jun 10; Vol. 17, pp. 1841156. Date of Electronic Publication: 2026 Jun 10 (Print Publication: 2026).
Publication Type: Case Reports; Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Trisomy 8 clonal expansion during disease progression and azacitidine resistance in VEXAS syndrome: a case report.
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  Data: <searchLink fieldCode="AU" term="%22Sato+K%22">Sato K</searchLink>; Department of Hematology, Japanese Red Cross Nagano Hospital, Nagano, Japan.<br /><searchLink fieldCode="AU" term="%22Zaimoku+Y%22">Zaimoku Y</searchLink>; Department of Hematology, Kanazawa University Hospital, Kanazawa, Japan.; Innovate Clinical Research Center, Kanazawa University Hospital, Kanazawa, Japan.<br /><searchLink fieldCode="AU" term="%22Kano+Y%22">Kano Y</searchLink>; Department of Clinical Laboratory Science, Division of Health Sciences, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan.<br /><searchLink fieldCode="AU" term="%22Kobayashi+M%22">Kobayashi M</searchLink>; Department of Clinical Laboratory Science, Division of Health Sciences, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan.<br /><searchLink fieldCode="AU" term="%22Kazama+S%22">Kazama S</searchLink>; Department of Hematology, Japanese Red Cross Nagano Hospital, Nagano, Japan.<br /><searchLink fieldCode="AU" term="%22Morikawa+T%22">Morikawa T</searchLink>; Department of Hematology, Japanese Red Cross Nagano Hospital, Nagano, Japan.<br /><searchLink fieldCode="AU" term="%22Kazumoto+H%22">Kazumoto H</searchLink>; Department of Hematology, Japanese Red Cross Nagano Hospital, Nagano, Japan.<br /><searchLink fieldCode="AU" term="%22Ishii+W%22">Ishii W</searchLink>; Department of Rheumatology, Japanese Red Cross Nagano Hospital, Nagano, Japan.<br /><searchLink fieldCode="AU" term="%22Ueki+T%22">Ueki T</searchLink>; Department of Hematology, Japanese Red Cross Nagano Hospital, Nagano, Japan.<br /><searchLink fieldCode="AU" term="%22Sumi+M%22">Sumi M</searchLink>; Department of Hematology, Japanese Red Cross Nagano Hospital, Nagano, Japan.<br /><searchLink fieldCode="AU" term="%22Kobayashi+H%22">Kobayashi H</searchLink>; Department of Hematology, Japanese Red Cross Nagano Hospital, Nagano, Japan.<br /><searchLink fieldCode="AU" term="%22Nannya+Y%22">Nannya Y</searchLink>; Division of Hematopoietic Disease Control, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Ogawa+S%22">Ogawa S</searchLink>; Department of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan.; Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto, Japan.; Department of Innovative Medicine, Faculty of Medicine, Kindai University, Osakasayama, Japan.<br /><searchLink fieldCode="AU" term="%22Ichikawa+N%22">Ichikawa N</searchLink>; Department of Medical Oncology, Japanese Red Cross Nagano Hospital, Nagano, Japan.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2026 Jun 10; Vol. 17, pp. 1841156. <i>Date of Electronic Publication: </i>2026 Jun 10 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
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