Small interfering RNA-mediated silencing of mutant NPM1 suppresses acute myeloid leukemia via reversing KAT7 and p300-mediated histone acetylation.
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| Title: | Small interfering RNA-mediated silencing of mutant NPM1 suppresses acute myeloid leukemia via reversing KAT7 and p300-mediated histone acetylation. |
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| Authors: | Hou Y; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiang'an Hospital, Xiang An Biomedicine Laboratory, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China., Xing Y; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiang'an Hospital, Xiang An Biomedicine Laboratory, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China., Chen C; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiang'an Hospital, Xiang An Biomedicine Laboratory, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China., Su D; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiang'an Hospital, Xiang An Biomedicine Laboratory, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China., Zhou Z; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiang'an Hospital, Xiang An Biomedicine Laboratory, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China., Ye Y; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiang'an Hospital, Xiang An Biomedicine Laboratory, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China., Lai Z; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiang'an Hospital, Xiang An Biomedicine Laboratory, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China., Peng Z; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiang'an Hospital, Xiang An Biomedicine Laboratory, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China., Cai H; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiang'an Hospital, Xiang An Biomedicine Laboratory, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China., Sun M; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiang'an Hospital, Xiang An Biomedicine Laboratory, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China., Liu Y; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiang'an Hospital, Xiang An Biomedicine Laboratory, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China., Yang B; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiang'an Hospital, Xiang An Biomedicine Laboratory, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China., Huang H; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiang'an Hospital, Xiang An Biomedicine Laboratory, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China., Li Z; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiang'an Hospital, Xiang An Biomedicine Laboratory, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China., Li J; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiang'an Hospital, Xiang An Biomedicine Laboratory, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China., Li J; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiang'an Hospital, Xiang An Biomedicine Laboratory, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China., Gao H; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiang'an Hospital, Xiang An Biomedicine Laboratory, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China., Li J; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiang'an Hospital, Xiang An Biomedicine Laboratory, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China., Zhao H; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiang'an Hospital, Xiang An Biomedicine Laboratory, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China., Shi Y; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiang'an Hospital, Xiang An Biomedicine Laboratory, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China., Chen Q; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiang'an Hospital, Xiang An Biomedicine Laboratory, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China., Long J; Department of Hematology, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China., Hu J; Shanghai Institute of Hematology Blood & Marrow Transplantation Center, Department of Hematology, Collaborative Innovation Center of Hematology, Rui Jin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China., Zhou D; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiang'an Hospital, Xiang An Biomedicine Laboratory, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China. dwzhou@xmu.edu.cn., Chen L; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiang'an Hospital, Xiang An Biomedicine Laboratory, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China. chenlanfen@xmu.edu.cn. |
| Source: | Leukemia [Leukemia] 2026 Jun 26. Date of Electronic Publication: 2026 Jun 26. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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