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KIF7 promotes the proliferation of clear cell renal cell carcinoma by activating the WNT/β-catenin signaling pathway.

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Title: KIF7 promotes the proliferation of clear cell renal cell carcinoma by activating the WNT/β-catenin signaling pathway.
Authors: Wang Y; Department of Basic Innovation Research, Beijing Hospital, National Center for Gerontology, The Key Laboratory of Geriatrics of NHC, Beijing Key Laboratory of Aging Mechanism and Intervention Research on Aging-Related Diseases, Institute of Geriatric Medicine, National Clinical Research Center for Gerontology, Chinese Academy of Medical Sciences, Beijing, The People's Republic of China.; Medical School, University of Chinese Academy of Sciences, Beijing, People's Republic of China., Wang XM; Department of Basic Innovation Research, Beijing Hospital, National Center for Gerontology, The Key Laboratory of Geriatrics of NHC, Beijing Key Laboratory of Aging Mechanism and Intervention Research on Aging-Related Diseases, Institute of Geriatric Medicine, National Clinical Research Center for Gerontology, Chinese Academy of Medical Sciences, Beijing, The People's Republic of China., Huo D; Department of Basic Innovation Research, Beijing Hospital, National Center for Gerontology, The Key Laboratory of Geriatrics of NHC, Beijing Key Laboratory of Aging Mechanism and Intervention Research on Aging-Related Diseases, Institute of Geriatric Medicine, National Clinical Research Center for Gerontology, Chinese Academy of Medical Sciences, Beijing, The People's Republic of China.; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, USA., Wang SB; Department of Basic Innovation Research, Beijing Hospital, National Center for Gerontology, The Key Laboratory of Geriatrics of NHC, Beijing Key Laboratory of Aging Mechanism and Intervention Research on Aging-Related Diseases, Institute of Geriatric Medicine, National Clinical Research Center for Gerontology, Chinese Academy of Medical Sciences, Beijing, The People's Republic of China., Liu QY; Department of Basic Innovation Research, Beijing Hospital, National Center for Gerontology, The Key Laboratory of Geriatrics of NHC, Beijing Key Laboratory of Aging Mechanism and Intervention Research on Aging-Related Diseases, Institute of Geriatric Medicine, National Clinical Research Center for Gerontology, Chinese Academy of Medical Sciences, Beijing, The People's Republic of China., Pang J; Department of Basic Innovation Research, Beijing Hospital, National Center for Gerontology, The Key Laboratory of Geriatrics of NHC, Beijing Key Laboratory of Aging Mechanism and Intervention Research on Aging-Related Diseases, Institute of Geriatric Medicine, National Clinical Research Center for Gerontology, Chinese Academy of Medical Sciences, Beijing, The People's Republic of China., Shen T; Department of Basic Innovation Research, Beijing Hospital, National Center for Gerontology, The Key Laboratory of Geriatrics of NHC, Beijing Key Laboratory of Aging Mechanism and Intervention Research on Aging-Related Diseases, Institute of Geriatric Medicine, National Clinical Research Center for Gerontology, Chinese Academy of Medical Sciences, Beijing, The People's Republic of China., Cui D; Department of Pathology, Beijing Hospital, The Key Laboratory of Geriatrics of NHC, Institute of Geriatric Medicine, National Center of Gerontology, National Clinical Research Center for Gerontology, Chinese Academy of Medical Sciences, Beijing, People's Republic of China., Zhao WJ; Shenzhen Key Laboratory of Genome Manipulation and Biosynthesis, State Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, People's Republic of China.; School of Pharmacy, Faculty of Medicine, Macau University of Science and Technology, Macau, 999078, People's Republic of China., Luo QF; Medical School, University of Chinese Academy of Sciences, Beijing, People's Republic of China.; Department of Gastroenterology, Beijing Hospital, The Key Laboratory of Geriatrics of NHC, Institute of Geriatric Medicine, National Center of Gerontology, National Clinical Research Center for Gerontology, Chinese Academy of Medical Sciences, Beijing, People's Republic of China., Li N; Shenzhen Key Laboratory of Genome Manipulation and Biosynthesis, State Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, People's Republic of China., Chen AQ; Department of Nephrology, Beijing Hospital, The Key Laboratory of Geriatrics of NHC, Institute of Geriatric Medicine, National Center of Gerontology, National Clinical Research Center for Gerontology, Chinese Academy of Medical Sciences, Beijing, People's Republic of China. chenaiqun3735@bjhmoh.cn., Cui J; Department of Basic Innovation Research, Beijing Hospital, National Center for Gerontology, The Key Laboratory of Geriatrics of NHC, Beijing Key Laboratory of Aging Mechanism and Intervention Research on Aging-Related Diseases, Institute of Geriatric Medicine, National Clinical Research Center for Gerontology, Chinese Academy of Medical Sciences, Beijing, The People's Republic of China. cuiju4366@bjhmoh.cn.; Medical School, University of Chinese Academy of Sciences, Beijing, People's Republic of China. cuiju4366@bjhmoh.cn.
Source: Clinical and experimental medicine [Clin Exp Med] 2026 Jun 28. Date of Electronic Publication: 2026 Jun 28.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Italia Country of Publication: Italy NLM ID: 100973405 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1591-9528 (Electronic) Linking ISSN: 15918890 NLM ISO Abbreviation: Clin Exp Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: KIF7 promotes the proliferation of clear cell renal cell carcinoma by activating the WNT/β-catenin signaling pathway.
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  Data: <searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Department of Basic Innovation Research, Beijing Hospital, National Center for Gerontology, The Key Laboratory of Geriatrics of NHC, Beijing Key Laboratory of Aging Mechanism and Intervention Research on Aging-Related Diseases, Institute of Geriatric Medicine, National Clinical Research Center for Gerontology, Chinese Academy of Medical Sciences, Beijing, The People's Republic of China.; Medical School, University of Chinese Academy of Sciences, Beijing, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wang+XM%22">Wang XM</searchLink>; Department of Basic Innovation Research, Beijing Hospital, National Center for Gerontology, The Key Laboratory of Geriatrics of NHC, Beijing Key Laboratory of Aging Mechanism and Intervention Research on Aging-Related Diseases, Institute of Geriatric Medicine, National Clinical Research Center for Gerontology, Chinese Academy of Medical Sciences, Beijing, The People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Huo+D%22">Huo D</searchLink>; Department of Basic Innovation Research, Beijing Hospital, National Center for Gerontology, The Key Laboratory of Geriatrics of NHC, Beijing Key Laboratory of Aging Mechanism and Intervention Research on Aging-Related Diseases, Institute of Geriatric Medicine, National Clinical Research Center for Gerontology, Chinese Academy of Medical Sciences, Beijing, The People's Republic of China.; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, USA.<br /><searchLink fieldCode="AU" term="%22Wang+SB%22">Wang SB</searchLink>; Department of Basic Innovation Research, Beijing Hospital, National Center for Gerontology, The Key Laboratory of Geriatrics of NHC, Beijing Key Laboratory of Aging Mechanism and Intervention Research on Aging-Related Diseases, Institute of Geriatric Medicine, National Clinical Research Center for Gerontology, Chinese Academy of Medical Sciences, Beijing, The People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Liu+QY%22">Liu QY</searchLink>; Department of Basic Innovation Research, Beijing Hospital, National Center for Gerontology, The Key Laboratory of Geriatrics of NHC, Beijing Key Laboratory of Aging Mechanism and Intervention Research on Aging-Related Diseases, Institute of Geriatric Medicine, National Clinical Research Center for Gerontology, Chinese Academy of Medical Sciences, Beijing, The People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Pang+J%22">Pang J</searchLink>; Department of Basic Innovation Research, Beijing Hospital, National Center for Gerontology, The Key Laboratory of Geriatrics of NHC, Beijing Key Laboratory of Aging Mechanism and Intervention Research on Aging-Related Diseases, Institute of Geriatric Medicine, National Clinical Research Center for Gerontology, Chinese Academy of Medical Sciences, Beijing, The People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Shen+T%22">Shen T</searchLink>; Department of Basic Innovation Research, Beijing Hospital, National Center for Gerontology, The Key Laboratory of Geriatrics of NHC, Beijing Key Laboratory of Aging Mechanism and Intervention Research on Aging-Related Diseases, Institute of Geriatric Medicine, National Clinical Research Center for Gerontology, Chinese Academy of Medical Sciences, Beijing, The People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Cui+D%22">Cui D</searchLink>; Department of Pathology, Beijing Hospital, The Key Laboratory of Geriatrics of NHC, Institute of Geriatric Medicine, National Center of Gerontology, National Clinical Research Center for Gerontology, Chinese Academy of Medical Sciences, Beijing, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zhao+WJ%22">Zhao WJ</searchLink>; Shenzhen Key Laboratory of Genome Manipulation and Biosynthesis, State Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, People's Republic of China.; School of Pharmacy, Faculty of Medicine, Macau University of Science and Technology, Macau, 999078, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Luo+QF%22">Luo QF</searchLink>; Medical School, University of Chinese Academy of Sciences, Beijing, People's Republic of China.; Department of Gastroenterology, Beijing Hospital, The Key Laboratory of Geriatrics of NHC, Institute of Geriatric Medicine, National Center of Gerontology, National Clinical Research Center for Gerontology, Chinese Academy of Medical Sciences, Beijing, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Li+N%22">Li N</searchLink>; Shenzhen Key Laboratory of Genome Manipulation and Biosynthesis, State Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Chen+AQ%22">Chen AQ</searchLink>; Department of Nephrology, Beijing Hospital, The Key Laboratory of Geriatrics of NHC, Institute of Geriatric Medicine, National Center of Gerontology, National Clinical Research Center for Gerontology, Chinese Academy of Medical Sciences, Beijing, People's Republic of China. chenaiqun3735@bjhmoh.cn.<br /><searchLink fieldCode="AU" term="%22Cui+J%22">Cui J</searchLink>; Department of Basic Innovation Research, Beijing Hospital, National Center for Gerontology, The Key Laboratory of Geriatrics of NHC, Beijing Key Laboratory of Aging Mechanism and Intervention Research on Aging-Related Diseases, Institute of Geriatric Medicine, National Clinical Research Center for Gerontology, Chinese Academy of Medical Sciences, Beijing, The People's Republic of China. cuiju4366@bjhmoh.cn.; Medical School, University of Chinese Academy of Sciences, Beijing, People's Republic of China. cuiju4366@bjhmoh.cn.
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        Value: 10.1007/s10238-026-02203-6
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        Text: English
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              Text: 2026 Jun 28
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