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Engineered Heart Tissues Facilitate Noncoding Variant Studies in Cardiomyopathy.

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Title: Engineered Heart Tissues Facilitate Noncoding Variant Studies in Cardiomyopathy.
Authors: Weber ZT; Department of Human Genetics (Z.T.W., R.M.M., L.Z., A.G.T., I.M.S., X.L., M.A.N.), University of Chicago, IL., Monroe TO; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL (T.O.M., C.H., I.A.C., F.K., D.E.F., M.J.P., E.M.M.N.).; Now with Cardiovascular Research Institute, Icahn School of Medicine at Mt. Sinai (T.O.M.)., Holgren C; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL (T.O.M., C.H., I.A.C., F.K., D.E.F., M.J.P., E.M.M.N.)., Mitchell RM; Department of Human Genetics (Z.T.W., R.M.M., L.Z., A.G.T., I.M.S., X.L., M.A.N.), University of Chicago, IL., Zhang L; Department of Human Genetics (Z.T.W., R.M.M., L.Z., A.G.T., I.M.S., X.L., M.A.N.), University of Chicago, IL., Thornburg AG; Department of Human Genetics (Z.T.W., R.M.M., L.Z., A.G.T., I.M.S., X.L., M.A.N.), University of Chicago, IL., Salamone IM; Department of Human Genetics (Z.T.W., R.M.M., L.Z., A.G.T., I.M.S., X.L., M.A.N.), University of Chicago, IL., Chychula IA; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL (T.O.M., C.H., I.A.C., F.K., D.E.F., M.J.P., E.M.M.N.)., Karthik F; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL (T.O.M., C.H., I.A.C., F.K., D.E.F., M.J.P., E.M.M.N.)., Fullenkamp DE; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL (T.O.M., C.H., I.A.C., F.K., D.E.F., M.J.P., E.M.M.N.)., Puckelwartz MJ; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL (T.O.M., C.H., I.A.C., F.K., D.E.F., M.J.P., E.M.M.N.)., Liu X; Department of Human Genetics (Z.T.W., R.M.M., L.Z., A.G.T., I.M.S., X.L., M.A.N.), University of Chicago, IL.; Section of Genetic Medicine, Department of Medicine (X.L.), University of Chicago, IL., McNally EM; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL (T.O.M., C.H., I.A.C., F.K., D.E.F., M.J.P., E.M.M.N.)., Nóbrega MA; Department of Human Genetics (Z.T.W., R.M.M., L.Z., A.G.T., I.M.S., X.L., M.A.N.), University of Chicago, IL.
Source: Circulation research [Circ Res] 2026 Jun 29. Date of Electronic Publication: 2026 Jun 29.
Publication Type: Journal Article
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0047103 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4571 (Electronic) Linking ISSN: 00097330 NLM ISO Abbreviation: Circ Res Subsets: MEDLINE
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  Data: Engineered Heart Tissues Facilitate Noncoding Variant Studies in Cardiomyopathy.
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  Data: <searchLink fieldCode="AU" term="%22Weber+ZT%22">Weber ZT</searchLink>; Department of Human Genetics (Z.T.W., R.M.M., L.Z., A.G.T., I.M.S., X.L., M.A.N.), University of Chicago, IL.<br /><searchLink fieldCode="AU" term="%22Monroe+TO%22">Monroe TO</searchLink>; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL (T.O.M., C.H., I.A.C., F.K., D.E.F., M.J.P., E.M.M.N.).; Now with Cardiovascular Research Institute, Icahn School of Medicine at Mt. Sinai (T.O.M.).<br /><searchLink fieldCode="AU" term="%22Holgren+C%22">Holgren C</searchLink>; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL (T.O.M., C.H., I.A.C., F.K., D.E.F., M.J.P., E.M.M.N.).<br /><searchLink fieldCode="AU" term="%22Mitchell+RM%22">Mitchell RM</searchLink>; Department of Human Genetics (Z.T.W., R.M.M., L.Z., A.G.T., I.M.S., X.L., M.A.N.), University of Chicago, IL.<br /><searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; Department of Human Genetics (Z.T.W., R.M.M., L.Z., A.G.T., I.M.S., X.L., M.A.N.), University of Chicago, IL.<br /><searchLink fieldCode="AU" term="%22Thornburg+AG%22">Thornburg AG</searchLink>; Department of Human Genetics (Z.T.W., R.M.M., L.Z., A.G.T., I.M.S., X.L., M.A.N.), University of Chicago, IL.<br /><searchLink fieldCode="AU" term="%22Salamone+IM%22">Salamone IM</searchLink>; Department of Human Genetics (Z.T.W., R.M.M., L.Z., A.G.T., I.M.S., X.L., M.A.N.), University of Chicago, IL.<br /><searchLink fieldCode="AU" term="%22Chychula+IA%22">Chychula IA</searchLink>; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL (T.O.M., C.H., I.A.C., F.K., D.E.F., M.J.P., E.M.M.N.).<br /><searchLink fieldCode="AU" term="%22Karthik+F%22">Karthik F</searchLink>; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL (T.O.M., C.H., I.A.C., F.K., D.E.F., M.J.P., E.M.M.N.).<br /><searchLink fieldCode="AU" term="%22Fullenkamp+DE%22">Fullenkamp DE</searchLink>; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL (T.O.M., C.H., I.A.C., F.K., D.E.F., M.J.P., E.M.M.N.).<br /><searchLink fieldCode="AU" term="%22Puckelwartz+MJ%22">Puckelwartz MJ</searchLink>; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL (T.O.M., C.H., I.A.C., F.K., D.E.F., M.J.P., E.M.M.N.).<br /><searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; Department of Human Genetics (Z.T.W., R.M.M., L.Z., A.G.T., I.M.S., X.L., M.A.N.), University of Chicago, IL.; Section of Genetic Medicine, Department of Medicine (X.L.), University of Chicago, IL.<br /><searchLink fieldCode="AU" term="%22McNally+EM%22">McNally EM</searchLink>; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL (T.O.M., C.H., I.A.C., F.K., D.E.F., M.J.P., E.M.M.N.).<br /><searchLink fieldCode="AU" term="%22Nóbrega+MA%22">Nóbrega MA</searchLink>; Department of Human Genetics (Z.T.W., R.M.M., L.Z., A.G.T., I.M.S., X.L., M.A.N.), University of Chicago, IL.
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      – Type: doi
        Value: 10.1161/CIRCRESAHA.125.327506
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        Text: English
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      – TitleFull: Engineered Heart Tissues Facilitate Noncoding Variant Studies in Cardiomyopathy.
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              Text: 2026 Jun 29
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