Targeting Bruton tyrosine kinase with acalabrutinib attenuates murine sclerodermatous chronic graft versus host disease.

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Title: Targeting Bruton tyrosine kinase with acalabrutinib attenuates murine sclerodermatous chronic graft versus host disease.
Authors: Raguraman V; Division of Hematology and Medical Oncology, Department of Medicine, Ellis Fischel Cancer Center, University of Missouri, Columbia, MO, United States., Mysinger M; Division of Hematology & Blood and Marrow Transplantation, Department of Internal Medicine, Markey Cancer Center, University of Kentucky, Lexington, KY, United States., Verma M; Department of Biomedical Sciences, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV, United States., Mohiyuddin S; Division of Hematology and Medical Oncology, Department of Medicine, Ellis Fischel Cancer Center, University of Missouri, Columbia, MO, United States., Jabbour N; Department of Pathology and Laboratory Medicine, University of Kentucky, Lexington, KY, United States., Kesler M; Department of Pathology and Laboratory Medicine, University of Kentucky, Lexington, KY, United States., Joshi T; Department of Biomedical Sciences, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV, United States.; Department of Biomedical Informatics, Biostatistics and Medical Epidemiology, University of Missouri, Columbia, MO, United States., Palaniyandi S; Division of Hematology and Medical Oncology, Department of Medicine, Ellis Fischel Cancer Center, University of Missouri, Columbia, MO, United States.; Division of Hematology & Blood and Marrow Transplantation, Department of Internal Medicine, Markey Cancer Center, University of Kentucky, Lexington, KY, United States., Hildebrandt GC; Division of Hematology and Medical Oncology, Department of Medicine, Ellis Fischel Cancer Center, University of Missouri, Columbia, MO, United States.; Division of Hematology & Blood and Marrow Transplantation, Department of Internal Medicine, Markey Cancer Center, University of Kentucky, Lexington, KY, United States.
Source: Frontiers in immunology [Front Immunol] 2026 Jun 11; Vol. 17, pp. 1843217. Date of Electronic Publication: 2026 Jun 11 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
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  Data: Targeting Bruton tyrosine kinase with acalabrutinib attenuates murine sclerodermatous chronic graft versus host disease.
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  Data: <searchLink fieldCode="AU" term="%22Raguraman+V%22">Raguraman V</searchLink>; Division of Hematology and Medical Oncology, Department of Medicine, Ellis Fischel Cancer Center, University of Missouri, Columbia, MO, United States.<br /><searchLink fieldCode="AU" term="%22Mysinger+M%22">Mysinger M</searchLink>; Division of Hematology & Blood and Marrow Transplantation, Department of Internal Medicine, Markey Cancer Center, University of Kentucky, Lexington, KY, United States.<br /><searchLink fieldCode="AU" term="%22Verma+M%22">Verma M</searchLink>; Department of Biomedical Sciences, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV, United States.<br /><searchLink fieldCode="AU" term="%22Mohiyuddin+S%22">Mohiyuddin S</searchLink>; Division of Hematology and Medical Oncology, Department of Medicine, Ellis Fischel Cancer Center, University of Missouri, Columbia, MO, United States.<br /><searchLink fieldCode="AU" term="%22Jabbour+N%22">Jabbour N</searchLink>; Department of Pathology and Laboratory Medicine, University of Kentucky, Lexington, KY, United States.<br /><searchLink fieldCode="AU" term="%22Kesler+M%22">Kesler M</searchLink>; Department of Pathology and Laboratory Medicine, University of Kentucky, Lexington, KY, United States.<br /><searchLink fieldCode="AU" term="%22Joshi+T%22">Joshi T</searchLink>; Department of Biomedical Sciences, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV, United States.; Department of Biomedical Informatics, Biostatistics and Medical Epidemiology, University of Missouri, Columbia, MO, United States.<br /><searchLink fieldCode="AU" term="%22Palaniyandi+S%22">Palaniyandi S</searchLink>; Division of Hematology and Medical Oncology, Department of Medicine, Ellis Fischel Cancer Center, University of Missouri, Columbia, MO, United States.; Division of Hematology & Blood and Marrow Transplantation, Department of Internal Medicine, Markey Cancer Center, University of Kentucky, Lexington, KY, United States.<br /><searchLink fieldCode="AU" term="%22Hildebrandt+GC%22">Hildebrandt GC</searchLink>; Division of Hematology and Medical Oncology, Department of Medicine, Ellis Fischel Cancer Center, University of Missouri, Columbia, MO, United States.; Division of Hematology & Blood and Marrow Transplantation, Department of Internal Medicine, Markey Cancer Center, University of Kentucky, Lexington, KY, United States.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2026 Jun 11; Vol. 17, pp. 1843217. <i>Date of Electronic Publication: </i>2026 Jun 11 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
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        Value: 10.3389/fimmu.2026.1843217
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              Text: 2026 Jun 11
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