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Comparison of Early Intrapleural Fibrinolytic Therapy, Versus Administration After Failure of Intercostal Drainage in Children with Empyema Thoracis: A Systematic Review.

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Title: Comparison of Early Intrapleural Fibrinolytic Therapy, Versus Administration After Failure of Intercostal Drainage in Children with Empyema Thoracis: A Systematic Review.
Authors: Jain L; Advanced Centre for Evidence Based Child Health, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.; Pediatric Empyema Guideline Project, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India., Kaur S; Vardhman Mahavir Medical College & Safdarjung Hospital, New Delhi, India., Sivabalan S; Rainbow Children's Hospital (RCH), Anna Nagar, Chennai, Tamil Nadu, India., Bafna S; Department of Pediatrics, Bharati Vidyapeeth University Medical College, Hospital, Pune, Maharashtra, India., Agarwal D; Department of Pediatrics, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, India., Pradhan P; Advanced Centre for Evidence Based Child Health, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.; Pediatric Empyema Guideline Project, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India., Mathew JL; Advanced Centre for Evidence Based Child Health, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. dr.joseph.l.mathew@gmail.com.; Pediatric Empyema Guideline Project, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. dr.joseph.l.mathew@gmail.com.; Department of Pediatrics, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India. dr.joseph.l.mathew@gmail.com.; DHR Technical Resource Hub for Evidence Based Guidelines, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. dr.joseph.l.mathew@gmail.com.
Source: Indian pediatrics [Indian Pediatr] 2026 Jun 29. Date of Electronic Publication: 2026 Jun 29.
Publication Type: Journal Article; Review
Journal Info: Publisher: Indian Pediatrics Country of Publication: India NLM ID: 2985062R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0974-7559 (Electronic) Linking ISSN: 00196061 NLM ISO Abbreviation: Indian Pediatr Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Comparison of Early Intrapleural Fibrinolytic Therapy, Versus Administration After Failure of Intercostal Drainage in Children with Empyema Thoracis: A Systematic Review.
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  Data: <searchLink fieldCode="AU" term="%22Jain+L%22">Jain L</searchLink>; Advanced Centre for Evidence Based Child Health, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.; Pediatric Empyema Guideline Project, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.<br /><searchLink fieldCode="AU" term="%22Kaur+S%22">Kaur S</searchLink>; Vardhman Mahavir Medical College & Safdarjung Hospital, New Delhi, India.<br /><searchLink fieldCode="AU" term="%22Sivabalan+S%22">Sivabalan S</searchLink>; Rainbow Children's Hospital (RCH), Anna Nagar, Chennai, Tamil Nadu, India.<br /><searchLink fieldCode="AU" term="%22Bafna+S%22">Bafna S</searchLink>; Department of Pediatrics, Bharati Vidyapeeth University Medical College, Hospital, Pune, Maharashtra, India.<br /><searchLink fieldCode="AU" term="%22Agarwal+D%22">Agarwal D</searchLink>; Department of Pediatrics, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, India.<br /><searchLink fieldCode="AU" term="%22Pradhan+P%22">Pradhan P</searchLink>; Advanced Centre for Evidence Based Child Health, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.; Pediatric Empyema Guideline Project, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.<br /><searchLink fieldCode="AU" term="%22Mathew+JL%22">Mathew JL</searchLink>; Advanced Centre for Evidence Based Child Health, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. dr.joseph.l.mathew@gmail.com.; Pediatric Empyema Guideline Project, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. dr.joseph.l.mathew@gmail.com.; Department of Pediatrics, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India. dr.joseph.l.mathew@gmail.com.; DHR Technical Resource Hub for Evidence Based Guidelines, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. dr.joseph.l.mathew@gmail.com.
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  Data: <searchLink fieldCode="JN" term="%222985062R%22">Indian pediatrics</searchLink> [Indian Pediatr] 2026 Jun 29. <i>Date of Electronic Publication: </i>2026 Jun 29.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Indian+Pediatrics%22">Indian Pediatrics </searchLink><i>Country of Publication: </i>India <i>NLM ID: </i>2985062R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>0974-7559 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200196061%22">00196061 </searchLink><i>NLM ISO Abbreviation: </i>Indian Pediatr <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s13312-026-00380-x
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      – TitleFull: Comparison of Early Intrapleural Fibrinolytic Therapy, Versus Administration After Failure of Intercostal Drainage in Children with Empyema Thoracis: A Systematic Review.
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              Text: 2026 Jun 29
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