Detecting atheromatous plaques in the aortic arch or supra-aortic arteries for more accurate stroke subtype classification.

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Title: Detecting atheromatous plaques in the aortic arch or supra-aortic arteries for more accurate stroke subtype classification.
Authors: Cui, Xiaoyang (AUTHOR), Wu, Simiao (AUTHOR), Zeng, Quantao (AUTHOR), Xiao, Jiahe (AUTHOR), Liu, Ming (AUTHOR)
Source: International Journal of Neuroscience. Feb2015, Vol. 125 Issue 2, p123-129. 7p.
Subjects: Atherosclerotic plaque, Thoracic aorta, Stroke diagnosis, Intracranial arterial diseases, Etiology of diseases
Abstract: Introduction. To investigate the correlations of atheromatous plaques in the aortic arch or supra-aortic arteries with intracranial arterial stenosis and carotid plaques in stroke patients, and to determine whether taking these plaques into account will reduce the proportion of patients in the undetermined etiology group. Methods. We prospectively enrolled 308 ischemic stroke patients, whose clinical characteristics and A-S-C-O classifications were compared with analyses of intracranial arteries, carotid arteries, aortic arch, and supra-aortic arteries. Results. 125(40.6%) patients had plaques in the aortic arch or supra-aortic arteries, of which 106 (84.8%) had complex plaques. No correlations were observed between these plaques and carotid plaques ( p = 0.283) or intracranial arterial stenosis ( p = 0.097). After detecting the mobile thrombi in the aortic arch and supra-aortic arteries, the proportion of patients in the atherothrombosis group was increased from 33.8% to 55.5% ( p = 0.00), whereas the proportion of patients in stroke of undetermined etiology group was decreased from 19.2% to 11.0% ( p = 0.00). Discussion. Examining only the carotid and intracranial arteries may not provide adequate information about large arteries in stroke patients. Therefore, it would be better to include a search for relevant plaques in the aortic arch or supra-aortic arteries in modern stroke workup, for it may lead to more accurate stroke subtype classification and guide secondary prevention. [ABSTRACT FROM AUTHOR]
Copyright of International Journal of Neuroscience is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Label: Title
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  Data: Detecting atheromatous plaques in the aortic arch or supra-aortic arteries for more accurate stroke subtype classification.
– Name: Author
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  Data: <searchLink fieldCode="AR" term="%22Cui%2C+Xiaoyang%22">Cui, Xiaoyang</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wu%2C+Simiao%22">Wu, Simiao</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zeng%2C+Quantao%22">Zeng, Quantao</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Xiao%2C+Jiahe%22">Xiao, Jiahe</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Liu%2C+Ming%22">Liu, Ming</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22International+Journal+of+Neuroscience%22">International Journal of Neuroscience</searchLink>. Feb2015, Vol. 125 Issue 2, p123-129. 7p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Atherosclerotic+plaque%22">Atherosclerotic plaque</searchLink><br /><searchLink fieldCode="DE" term="%22Thoracic+aorta%22">Thoracic aorta</searchLink><br /><searchLink fieldCode="DE" term="%22Stroke+diagnosis%22">Stroke diagnosis</searchLink><br /><searchLink fieldCode="DE" term="%22Intracranial+arterial+diseases%22">Intracranial arterial diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Etiology+of+diseases%22">Etiology of diseases</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Introduction. To investigate the correlations of atheromatous plaques in the aortic arch or supra-aortic arteries with intracranial arterial stenosis and carotid plaques in stroke patients, and to determine whether taking these plaques into account will reduce the proportion of patients in the undetermined etiology group. Methods. We prospectively enrolled 308 ischemic stroke patients, whose clinical characteristics and A-S-C-O classifications were compared with analyses of intracranial arteries, carotid arteries, aortic arch, and supra-aortic arteries. Results. 125(40.6%) patients had plaques in the aortic arch or supra-aortic arteries, of which 106 (84.8%) had complex plaques. No correlations were observed between these plaques and carotid plaques ( p = 0.283) or intracranial arterial stenosis ( p = 0.097). After detecting the mobile thrombi in the aortic arch and supra-aortic arteries, the proportion of patients in the atherothrombosis group was increased from 33.8% to 55.5% ( p = 0.00), whereas the proportion of patients in stroke of undetermined etiology group was decreased from 19.2% to 11.0% ( p = 0.00). Discussion. Examining only the carotid and intracranial arteries may not provide adequate information about large arteries in stroke patients. Therefore, it would be better to include a search for relevant plaques in the aortic arch or supra-aortic arteries in modern stroke workup, for it may lead to more accurate stroke subtype classification and guide secondary prevention. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of International Journal of Neuroscience is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.3109/00207454.2014.915825
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        Text: English
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        Type: general
      – SubjectFull: Thoracic aorta
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      – SubjectFull: Stroke diagnosis
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      – SubjectFull: Intracranial arterial diseases
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      – SubjectFull: Etiology of diseases
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              Text: Feb2015
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              Y: 2015
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