The S-cone electroretinogram: a comparison of techniques, normative data and age-related variation.

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Title: The S-cone electroretinogram: a comparison of techniques, normative data and age-related variation.
Authors: Chiti, Zohreh, North, Rachel V., Mortlock, Katharine E., Drasdo, Neville
Source: Ophthalmic & Physiological Optics. Jul2003, Vol. 23 Issue 4, p370-376. 7p.
Subjects: Retinoscopy, Eye examination, Ocular manifestations of general diseases, Eye diseases
Abstract: Abstract The blue sensitive mechanism in human colour vision is highly susceptible to damage in ocular disease. There is a need for objective methods to assess this and several methods of recording the blue cone (S-cone) electroretinogram (ERG) have been described. We therefore compared a silent substitution technique (SST) and a selective adaptation technique (SAT) using a novel combination of optical filters, on 24 normal subjects. The age-related variation in the S-cone ERG was also investigated in a further 73 normal subjects. S-cone ERGs elicited by SAT were of higher amplitude, (p < 0.001) with smaller coefficients of variation than those elicited with SST. The SST method has already been shown to be highly sensitive in primary open angle glaucoma and, unlike SAT, has no significant age related variation. However, the results of this study suggest that the new, SAT method may prove to be more convenient and effective in clinical practice, provided that age norms are applied. [ABSTRACT FROM AUTHOR]
Copyright of Ophthalmic & Physiological Optics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Retinoscopy%22&quot;&gt;Retinoscopy&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Eye+examination%22&quot;&gt;Eye examination&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Ocular+manifestations+of+general+diseases%22&quot;&gt;Ocular manifestations of general diseases&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Eye+diseases%22&quot;&gt;Eye diseases&lt;/searchLink&gt;
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  Data: Abstract The blue sensitive mechanism in human colour vision is highly susceptible to damage in ocular disease. There is a need for objective methods to assess this and several methods of recording the blue cone (S-cone) electroretinogram (ERG) have been described. We therefore compared a silent substitution technique (SST) and a selective adaptation technique (SAT) using a novel combination of optical filters, on 24 normal subjects. The age-related variation in the S-cone ERG was also investigated in a further 73 normal subjects. S-cone ERGs elicited by SAT were of higher amplitude, (p &lt; 0.001) with smaller coefficients of variation than those elicited with SST. The SST method has already been shown to be highly sensitive in primary open angle glaucoma and, unlike SAT, has no significant age related variation. However, the results of this study suggest that the new, SAT method may prove to be more convenient and effective in clinical practice, provided that age norms are applied. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of Ophthalmic &amp; Physiological Optics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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      – Type: doi
        Value: 10.1046/j.1475-1313.2003.00129.x
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      – Code: eng
        Text: English
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      – SubjectFull: Retinoscopy
        Type: general
      – SubjectFull: Eye examination
        Type: general
      – SubjectFull: Ocular manifestations of general diseases
        Type: general
      – SubjectFull: Eye diseases
        Type: general
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      – TitleFull: The S-cone electroretinogram: a comparison of techniques, normative data and age-related variation.
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            NameFull: Chiti, Zohreh
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            NameFull: North, Rachel V.
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            NameFull: Mortlock, Katharine E.
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            NameFull: Drasdo, Neville
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            – D: 01
              M: 07
              Text: Jul2003
              Type: published
              Y: 2003
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            – TitleFull: Ophthalmic & Physiological Optics
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