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Correlates and consequences of venous thromboembolism: the Iowa Women's Health Study.

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Title: Correlates and consequences of venous thromboembolism: the Iowa Women's Health Study.
Authors: Lutsey PL (AUTHOR), Virnig BA (AUTHOR), Durham SB (AUTHOR), Steffen LM (AUTHOR), Hirsch AT (AUTHOR), Jacobs DR Jr. (AUTHOR), Folsom AR (AUTHOR)
Source: American Journal of Public Health. Aug2010, Vol. 100 Issue 8, p1506-1513. 8p.
Subjects: Thromboembolism, Diseases in older women, Women's conduct of life, Mortality, Demographic research, Disease research, Health surveys, Disease risk factors
Geographic Terms: Iowa
Abstract: Objectives. We sought to document incidence, case-fatality, and recurrence rates of venous thromboembolism (VTE) in women and to explore the relationship of demographic, lifestyle, and anthropometric factors to VTE incidence. Methods. Data from participants aged 55 to 69 years in the Iowa Women's Health Study were linked to Medicare data for 1986 through 2004 (n=40377) to identify hospitalized VTE patients. Results. A total of 2137 women developed VTE, yielding an incidence rate of 4.04 per 1000 person-years. The 28-day case-fatality rate was 7.7%, and the 1- year recurrence rate was 3.4%. Educational attainment, physical activity, and age at menopause were inversely associated with VTE. Risk of secondary (particularly cancer-related) VTE was higher among smokers than among those who had never smoked. Body mass index, waist circumference, waist-to-hip ratio, height, and diabetes were positively associated with VTE risk. Hormone replacement therapy use was associated with increased risk of idiopathic VTE. Conclusions. VTE is a significant source of morbidity and mortality in older women. Risk was elevated among women who were smokers, physically inactive, overweight, and diabetic, indicating that lifestyle contributes to VTE risk. [ABSTRACT FROM AUTHOR]
Copyright of American Journal of Public Health is the property of American Public Health Association and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Correlates and consequences of venous thromboembolism: the Iowa Women's Health Study.
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  Data: <searchLink fieldCode="AR" term="%22Lutsey+PL%22">Lutsey PL</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Virnig+BA%22">Virnig BA</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Durham+SB%22">Durham SB</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Steffen+LM%22">Steffen LM</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hirsch+AT%22">Hirsch AT</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Jacobs+DR+Jr%2E%22">Jacobs DR Jr.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Folsom+AR%22">Folsom AR</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22American+Journal+of+Public+Health%22">American Journal of Public Health</searchLink>. Aug2010, Vol. 100 Issue 8, p1506-1513. 8p.
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  Data: <searchLink fieldCode="DE" term="%22Thromboembolism%22">Thromboembolism</searchLink><br /><searchLink fieldCode="DE" term="%22Diseases+in+older+women%22">Diseases in older women</searchLink><br /><searchLink fieldCode="DE" term="%22Women's+conduct+of+life%22">Women's conduct of life</searchLink><br /><searchLink fieldCode="DE" term="%22Mortality%22">Mortality</searchLink><br /><searchLink fieldCode="DE" term="%22Demographic+research%22">Demographic research</searchLink><br /><searchLink fieldCode="DE" term="%22Disease+research%22">Disease research</searchLink><br /><searchLink fieldCode="DE" term="%22Health+surveys%22">Health surveys</searchLink><br /><searchLink fieldCode="DE" term="%22Disease+risk+factors%22">Disease risk factors</searchLink>
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  Data: <searchLink fieldCode="DE" term="%22Iowa%22">Iowa</searchLink>
– Name: Abstract
  Label: Abstract
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  Data: Objectives. We sought to document incidence, case-fatality, and recurrence rates of venous thromboembolism (VTE) in women and to explore the relationship of demographic, lifestyle, and anthropometric factors to VTE incidence. Methods. Data from participants aged 55 to 69 years in the Iowa Women's Health Study were linked to Medicare data for 1986 through 2004 (n=40377) to identify hospitalized VTE patients. Results. A total of 2137 women developed VTE, yielding an incidence rate of 4.04 per 1000 person-years. The 28-day case-fatality rate was 7.7%, and the 1- year recurrence rate was 3.4%. Educational attainment, physical activity, and age at menopause were inversely associated with VTE. Risk of secondary (particularly cancer-related) VTE was higher among smokers than among those who had never smoked. Body mass index, waist circumference, waist-to-hip ratio, height, and diabetes were positively associated with VTE risk. Hormone replacement therapy use was associated with increased risk of idiopathic VTE. Conclusions. VTE is a significant source of morbidity and mortality in older women. Risk was elevated among women who were smokers, physically inactive, overweight, and diabetic, indicating that lifestyle contributes to VTE risk. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
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  Data: <i>Copyright of American Journal of Public Health is the property of American Public Health Association and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.2105/AJPH.2008.157776
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        Text: English
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      – SubjectFull: Women's conduct of life
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