Symptoms of depression and impaired endothelial function in healthy adolescent women.
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| Title: | Symptoms of depression and impaired endothelial function in healthy adolescent women. |
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| Authors: | Tomfohr LM (AUTHOR), Martin TM (AUTHOR), Miller GE (AUTHOR) |
| Source: | Journal of Behavioral Medicine. Apr2008, Vol. 31 Issue 2, p137-143. 7p. |
| Subjects: | Diagnosis of mental depression, Depressed persons, Diseases in women, Coronary disease, Beck Depression Inventory |
| Abstract: | Depression is related to increased morbidity and mortality from coronary heart disease (CHD), but the underlying mechanisms are unclear. One possibility is that depressive symptoms influence CHD pathogenesis by fostering endothelial dysfunction. To evaluate this possibility, we studied one hundred and two adolescent women with no known or suspected major health problems. Depressive symptoms were assessed using the Beck Depression Inventory (BDI) and endothelial function with a non-invasive beat-to-beat plethysmographic recording of the finger arterial pulse-wave amplitude (PWA) before and after occlusion of the brachial artery. Regression analysis revealed a significant inverse relationship between depressive symptoms and endothelial function. This persisted after controlling for age, ethnicity, health practices and waist circumference. Depression explained 4-6% of the variance in endothelial function above and beyond the effects of covariates. Most patients in our sample had subclinical depressive symptoms, suggesting that even mild affective difficulties are capable of negatively influencing endothelial function in otherwise healthy youngsters. [ABSTRACT FROM AUTHOR] |
| Copyright of Journal of Behavioral Medicine is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 105749047 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Symptoms of depression and impaired endothelial function in healthy adolescent women. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Tomfohr+LM%22">Tomfohr LM</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Martin+TM%22">Martin TM</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Miller+GE%22">Miller GE</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Journal+of+Behavioral+Medicine%22">Journal of Behavioral Medicine</searchLink>. Apr2008, Vol. 31 Issue 2, p137-143. 7p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Diagnosis+of+mental+depression%22">Diagnosis of mental depression</searchLink><br /><searchLink fieldCode="DE" term="%22Depressed+persons%22">Depressed persons</searchLink><br /><searchLink fieldCode="DE" term="%22Diseases+in+women%22">Diseases in women</searchLink><br /><searchLink fieldCode="DE" term="%22Coronary+disease%22">Coronary disease</searchLink><br /><searchLink fieldCode="DE" term="%22Beck+Depression+Inventory%22">Beck Depression Inventory</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Depression is related to increased morbidity and mortality from coronary heart disease (CHD), but the underlying mechanisms are unclear. One possibility is that depressive symptoms influence CHD pathogenesis by fostering endothelial dysfunction. To evaluate this possibility, we studied one hundred and two adolescent women with no known or suspected major health problems. Depressive symptoms were assessed using the Beck Depression Inventory (BDI) and endothelial function with a non-invasive beat-to-beat plethysmographic recording of the finger arterial pulse-wave amplitude (PWA) before and after occlusion of the brachial artery. Regression analysis revealed a significant inverse relationship between depressive symptoms and endothelial function. This persisted after controlling for age, ethnicity, health practices and waist circumference. Depression explained 4-6% of the variance in endothelial function above and beyond the effects of covariates. Most patients in our sample had subclinical depressive symptoms, suggesting that even mild affective difficulties are capable of negatively influencing endothelial function in otherwise healthy youngsters. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Journal of Behavioral Medicine is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=105749047 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s10865-007-9141-4 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 7 StartPage: 137 Subjects: – SubjectFull: Diagnosis of mental depression Type: general – SubjectFull: Depressed persons Type: general – SubjectFull: Diseases in women Type: general – SubjectFull: Coronary disease Type: general – SubjectFull: Beck Depression Inventory Type: general Titles: – TitleFull: Symptoms of depression and impaired endothelial function in healthy adolescent women. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Tomfohr LM – PersonEntity: Name: NameFull: Martin TM – PersonEntity: Name: NameFull: Miller GE IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 04 Text: Apr2008 Type: published Y: 2008 Identifiers: – Type: issn-print Value: 01607715 Numbering: – Type: volume Value: 31 – Type: issue Value: 2 Titles: – TitleFull: Journal of Behavioral Medicine Type: main |
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