Safety and efficacy assessment of Chungpyesagan-tang for acute ischemic stroke.
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| Title: | Safety and efficacy assessment of Chungpyesagan-tang for acute ischemic stroke. |
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| Authors: | Jung WS (AUTHOR), Choi DJ (AUTHOR), Cho KH (AUTHOR), Lee KS (AUTHOR), Moon SK (AUTHOR), Kim YS (AUTHOR), Bae HS (AUTHOR), Choi BO (AUTHOR) |
| Source: | American Journal of Chinese Medicine. 2003, Vol. 31 Issue 2, p181-190. 10p. |
| Abstract: | Chungpyesagan-tang is one of the most well-known traditional herbal formulations frequently used for treatment of acute stroke in Korea. Therefore, this study aims to assess the clinical safety and efficacy of chungpyesagan-tang on acute ischemic stroke. We recruited acute cerebral infarction subjects within 1 week after onset time. Then, we prescribed chungpyesagan-tang to an Oriental medical treatment group (OM-group) for 2 weeks and enrolled a Western medical treatment group (WM-group) which received only Western biomedical care as a control. In this study, the OM-group was composed of 75 subjects. However, 14 of them dropped out, as two had progressive stroke while 12 complained of diarrhea. Thus, 61 cases were included in the analysis and compared to the 76 cases of the WM-group. The improvement of OM-group was better than that of the WM-group according to the National Institute of Health Stroke Scale (NIHSS), but not by the Modified Barthel Index (MBI). There were no definite abnormalities on labortory safety asessment. Therefore, we suggest that chungpyesagan-tang may have therapeutic effects, acting to reduce the severity of stroke and improving functional recovery without definite hepatic or renal toxicity when given for the first 2 weeks after a stroke. [ABSTRACT FROM AUTHOR] |
| Copyright of American Journal of Chinese Medicine is the property of World Scientific Publishing Company and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 106856724 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Safety and efficacy assessment of Chungpyesagan-tang for acute ischemic stroke. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Jung+WS%22">Jung WS</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Choi+DJ%22">Choi DJ</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Cho+KH%22">Cho KH</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lee+KS%22">Lee KS</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Moon+SK%22">Moon SK</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kim+YS%22">Kim YS</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Bae+HS%22">Bae HS</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Choi+BO%22">Choi BO</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22American+Journal+of+Chinese+Medicine%22">American Journal of Chinese Medicine</searchLink>. 2003, Vol. 31 Issue 2, p181-190. 10p. – Name: Abstract Label: Abstract Group: Ab Data: Chungpyesagan-tang is one of the most well-known traditional herbal formulations frequently used for treatment of acute stroke in Korea. Therefore, this study aims to assess the clinical safety and efficacy of chungpyesagan-tang on acute ischemic stroke. We recruited acute cerebral infarction subjects within 1 week after onset time. Then, we prescribed chungpyesagan-tang to an Oriental medical treatment group (OM-group) for 2 weeks and enrolled a Western medical treatment group (WM-group) which received only Western biomedical care as a control. In this study, the OM-group was composed of 75 subjects. However, 14 of them dropped out, as two had progressive stroke while 12 complained of diarrhea. Thus, 61 cases were included in the analysis and compared to the 76 cases of the WM-group. The improvement of OM-group was better than that of the WM-group according to the National Institute of Health Stroke Scale (NIHSS), but not by the Modified Barthel Index (MBI). There were no definite abnormalities on labortory safety asessment. Therefore, we suggest that chungpyesagan-tang may have therapeutic effects, acting to reduce the severity of stroke and improving functional recovery without definite hepatic or renal toxicity when given for the first 2 weeks after a stroke. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of American Journal of Chinese Medicine is the property of World Scientific Publishing Company and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1142/s0192415x03000898 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 10 StartPage: 181 Titles: – TitleFull: Safety and efficacy assessment of Chungpyesagan-tang for acute ischemic stroke. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Jung WS – PersonEntity: Name: NameFull: Choi DJ – PersonEntity: Name: NameFull: Cho KH – PersonEntity: Name: NameFull: Lee KS – PersonEntity: Name: NameFull: Moon SK – PersonEntity: Name: NameFull: Kim YS – PersonEntity: Name: NameFull: Bae HS – PersonEntity: Name: NameFull: Choi BO IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 05 Text: 2003 Type: published Y: 2003 Identifiers: – Type: issn-print Value: 0192415X Numbering: – Type: volume Value: 31 – Type: issue Value: 2 Titles: – TitleFull: American Journal of Chinese Medicine Type: main |
| ResultId | 1 |
