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Observational study of effect of intrauterine transfusions on outcome of fetal hydrops after parvovirus B19 infection.

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Title: Observational study of effect of intrauterine transfusions on outcome of fetal hydrops after parvovirus B19 infection.
Authors: Fairley CK (AUTHOR), Smoleniec JS (AUTHOR), Caul OE (AUTHOR), Miller E (AUTHOR), Fairley, C K (AUTHOR), Smoleniec, J S (AUTHOR), Caul, O E (AUTHOR), Miller, E (AUTHOR)
Source: Lancet. 11/18/1995, Vol. 346 Issue 8986, p1335-1337. 3p.
Abstract: The role of intrauterine transfusion for fetal hydrops arising from maternal paravirus B19 infection is unclear. 66 cases of fetal hydrops arising from B19 infection were reported in England and Wales between June, 1992, and September, 1994. In 29 cases the fetus was dead at the time of the first abnormal ultrasound or a therapeutic abortion as performed; 12 of the 38 alive at the first abnormal scan received intrauterine transfusions and 3 of the 12 died. 26 did not receive intrauterine transfusions and 13 died. After adjustment for the severity of the hydrops as assessed by the ultrasound and for gestational age, the odds of death among those who received an intrauterine transfusion was significantly less than among those who did not (odds ratio 0.14, 95% CI 0.02-0.96). These findings suggest that intrauterine transfusion will benefit some fetuses with hydrops arising from parvovirus B19 infection. [ABSTRACT FROM AUTHOR]
Copyright of Lancet is the property of Lancet and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Observational study of effect of intrauterine transfusions on outcome of fetal hydrops after parvovirus B19 infection.
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  Data: <searchLink fieldCode="AR" term="%22Fairley+CK%22">Fairley CK</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Smoleniec+JS%22">Smoleniec JS</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Caul+OE%22">Caul OE</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Miller+E%22">Miller E</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Fairley%2C+C+K%22">Fairley, C K</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Smoleniec%2C+J+S%22">Smoleniec, J S</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Caul%2C+O+E%22">Caul, O E</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Miller%2C+E%22">Miller, E</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Lancet%22">Lancet</searchLink>. 11/18/1995, Vol. 346 Issue 8986, p1335-1337. 3p.
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  Data: The role of intrauterine transfusion for fetal hydrops arising from maternal paravirus B19 infection is unclear. 66 cases of fetal hydrops arising from B19 infection were reported in England and Wales between June, 1992, and September, 1994. In 29 cases the fetus was dead at the time of the first abnormal ultrasound or a therapeutic abortion as performed; 12 of the 38 alive at the first abnormal scan received intrauterine transfusions and 3 of the 12 died. 26 did not receive intrauterine transfusions and 13 died. After adjustment for the severity of the hydrops as assessed by the ultrasound and for gestational age, the odds of death among those who received an intrauterine transfusion was significantly less than among those who did not (odds ratio 0.14, 95% CI 0.02-0.96). These findings suggest that intrauterine transfusion will benefit some fetuses with hydrops arising from parvovirus B19 infection. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Lancet is the property of Lancet and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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              Text: 11/18/1995
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