View in EDS PDF Full Text

Evaluation of pedometry as a patient-centered outcome in patients undergoing hematopoietic cell transplant (HCT): a comparison of pedometry and patient reports of symptoms, health, and quality of life.

Saved in:
Bibliographic Details
Title: Evaluation of pedometry as a patient-centered outcome in patients undergoing hematopoietic cell transplant (HCT): a comparison of pedometry and patient reports of symptoms, health, and quality of life.
Authors: Bennett, Antonia, Reeve, Bryce, Basch, Ethan, Mitchell, Sandra, Meeneghan, Mathew, Battaglini, Claudio, Smith-Ryan, Abbie, Phillips, Brett, Shea, Thomas, Wood, William, Bennett, Antonia V (AUTHOR), Reeve, Bryce B (AUTHOR), Basch, Ethan M (AUTHOR), Mitchell, Sandra A (AUTHOR), Battaglini, Claudio L (AUTHOR), Smith-Ryan, Abbie E (AUTHOR), Shea, Thomas C (AUTHOR), Wood, William A (AUTHOR)
Source: Quality of Life Research. Mar2016, Vol. 25 Issue 3, p535-546. 12p. 6 Charts, 4 Graphs.
Subjects: Hematopoietic stem cell transplantation, Patient-centered care, Symptoms, Quality of life, Self-evaluation, Comparative studies, Health outcome assessment, Health status indicators, Longitudinal method, Research methodology, Medical cooperation, Motor ability, Research, Activities of daily living, Evaluation research, Accelerometry, Cross-sectional method, Psychology
Abstract: Aims: We evaluated pedometry as a novel patient-centered outcome because it enables passive continuous assessment of activity and may provide information about the consequences of symptomatic toxicity complementary to self-report.Methods: Adult patients undergoing hematopoietic cell transplant (HCT) wore pedometers and completed PRO assessments during transplant hospitalization (4 weeks) and 4 weeks post-discharge. Patient reports of symptomatic treatment toxicities (single items from PRO-CTCAE, http://healthcaredelivery.cancer.gov/pro-ctcae ) and symptoms, physical health, mental health, and quality of life (PROMIS(®) Global-10, http://nih.promis.org ), assessed weekly with 7-day recall on Likert scales, were compared individually with pedometry data, summarized as average daily steps per week, using linear mixed models.Results: Thirty-two patients [mean age 55 (SD = 14), 63 % male, 84 % white, 56 % autologous, 43 % allogeneic] completed a mean 4.6 (SD = 1.5, range 1-8) evaluable assessments. Regression model coefficients (β) indicated within-person decrements in average daily steps were associated with increases in pain (β = -852; 852 fewer steps per unit increase in pain score, p < 0.001), fatigue (β = -886, p < 0.001), vomiting (β = -518, p < 0.01), shaking/chills (β = -587, p < 0.01), diarrhea (β = -719, p < 0.001), shortness of breath (β = -1018, p < 0.05), reduction in carrying out social activities (β = 705, p < 0.01) or physical activities (β = 618, p < 0.01), and global physical health (β = 101, p < 0.001), but not global mental health or quality of life.Conclusions: In this small sample of HCT recipients, more severe symptoms, impaired physical health, and restrictions in the performance of usual daily activities were associated with statistically significant decrements in objectively measured daily steps. Pedometry may be a valuable outcome measure and validation anchor in clinical research. [ABSTRACT FROM AUTHOR]
Copyright of Quality of Life Research is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
FullText Links:
  – Type: pdflink
Text:
  Availability: 0
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 113139870
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Evaluation of pedometry as a patient-centered outcome in patients undergoing hematopoietic cell transplant (HCT): a comparison of pedometry and patient reports of symptoms, health, and quality of life.
– Name: Author
  Label: Authors
  Group: Au
  Data: &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Bennett%2C+Antonia%22&quot;&gt;Bennett, Antonia&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Reeve%2C+Bryce%22&quot;&gt;Reeve, Bryce&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Basch%2C+Ethan%22&quot;&gt;Basch, Ethan&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Mitchell%2C+Sandra%22&quot;&gt;Mitchell, Sandra&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Meeneghan%2C+Mathew%22&quot;&gt;Meeneghan, Mathew&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Battaglini%2C+Claudio%22&quot;&gt;Battaglini, Claudio&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Smith-Ryan%2C+Abbie%22&quot;&gt;Smith-Ryan, Abbie&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Phillips%2C+Brett%22&quot;&gt;Phillips, Brett&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Shea%2C+Thomas%22&quot;&gt;Shea, Thomas&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Wood%2C+William%22&quot;&gt;Wood, William&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Bennett%2C+Antonia+V%22&quot;&gt;Bennett, Antonia V&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Reeve%2C+Bryce+B%22&quot;&gt;Reeve, Bryce B&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Basch%2C+Ethan+M%22&quot;&gt;Basch, Ethan M&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Mitchell%2C+Sandra+A%22&quot;&gt;Mitchell, Sandra A&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Battaglini%2C+Claudio+L%22&quot;&gt;Battaglini, Claudio L&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Smith-Ryan%2C+Abbie+E%22&quot;&gt;Smith-Ryan, Abbie E&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Shea%2C+Thomas+C%22&quot;&gt;Shea, Thomas C&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Wood%2C+William+A%22&quot;&gt;Wood, William A&lt;/searchLink&gt; (AUTHOR)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22Quality+of+Life+Research%22&quot;&gt;Quality of Life Research&lt;/searchLink&gt;. Mar2016, Vol. 25 Issue 3, p535-546. 12p. 6 Charts, 4 Graphs.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Hematopoietic+stem+cell+transplantation%22&quot;&gt;Hematopoietic stem cell transplantation&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Patient-centered+care%22&quot;&gt;Patient-centered care&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Symptoms%22&quot;&gt;Symptoms&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Quality+of+life%22&quot;&gt;Quality of life&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Self-evaluation%22&quot;&gt;Self-evaluation&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Comparative+studies%22&quot;&gt;Comparative studies&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Health+outcome+assessment%22&quot;&gt;Health outcome assessment&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Health+status+indicators%22&quot;&gt;Health status indicators&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Longitudinal+method%22&quot;&gt;Longitudinal method&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Research+methodology%22&quot;&gt;Research methodology&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Medical+cooperation%22&quot;&gt;Medical cooperation&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Motor+ability%22&quot;&gt;Motor ability&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Research%22&quot;&gt;Research&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Activities+of+daily+living%22&quot;&gt;Activities of daily living&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Evaluation+research%22&quot;&gt;Evaluation research&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Accelerometry%22&quot;&gt;Accelerometry&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Cross-sectional+method%22&quot;&gt;Cross-sectional method&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Psychology%22&quot;&gt;Psychology&lt;/searchLink&gt;
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: &lt;bold&gt;Aims: &lt;/bold&gt;We evaluated pedometry as a novel patient-centered outcome because it enables passive continuous assessment of activity and may provide information about the consequences of symptomatic toxicity complementary to self-report.&lt;bold&gt;Methods: &lt;/bold&gt;Adult patients undergoing hematopoietic cell transplant (HCT) wore pedometers and completed PRO assessments during transplant hospitalization (4 weeks) and 4 weeks post-discharge. Patient reports of symptomatic treatment toxicities (single items from PRO-CTCAE, http://healthcaredelivery.cancer.gov/pro-ctcae ) and symptoms, physical health, mental health, and quality of life (PROMIS(&#174;) Global-10, http://nih.promis.org ), assessed weekly with 7-day recall on Likert scales, were compared individually with pedometry data, summarized as average daily steps per week, using linear mixed models.&lt;bold&gt;Results: &lt;/bold&gt;Thirty-two patients [mean age 55 (SD = 14), 63 % male, 84 % white, 56 % autologous, 43 % allogeneic] completed a mean 4.6 (SD = 1.5, range 1-8) evaluable assessments. Regression model coefficients (β) indicated within-person decrements in average daily steps were associated with increases in pain (β = -852; 852 fewer steps per unit increase in pain score, p &lt; 0.001), fatigue (β = -886, p &lt; 0.001), vomiting (β = -518, p &lt; 0.01), shaking/chills (β = -587, p &lt; 0.01), diarrhea (β = -719, p &lt; 0.001), shortness of breath (β = -1018, p &lt; 0.05), reduction in carrying out social activities (β = 705, p &lt; 0.01) or physical activities (β = 618, p &lt; 0.01), and global physical health (β = 101, p &lt; 0.001), but not global mental health or quality of life.&lt;bold&gt;Conclusions: &lt;/bold&gt;In this small sample of HCT recipients, more severe symptoms, impaired physical health, and restrictions in the performance of usual daily activities were associated with statistically significant decrements in objectively measured daily steps. Pedometry may be a valuable outcome measure and validation anchor in clinical research. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: &lt;i&gt;Copyright of Quality of Life Research is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=113139870
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1007/s11136-015-1179-0
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 12
        StartPage: 535
    Subjects:
      – SubjectFull: Hematopoietic stem cell transplantation
        Type: general
      – SubjectFull: Patient-centered care
        Type: general
      – SubjectFull: Symptoms
        Type: general
      – SubjectFull: Quality of life
        Type: general
      – SubjectFull: Self-evaluation
        Type: general
      – SubjectFull: Comparative studies
        Type: general
      – SubjectFull: Health outcome assessment
        Type: general
      – SubjectFull: Health status indicators
        Type: general
      – SubjectFull: Longitudinal method
        Type: general
      – SubjectFull: Research methodology
        Type: general
      – SubjectFull: Medical cooperation
        Type: general
      – SubjectFull: Motor ability
        Type: general
      – SubjectFull: Research
        Type: general
      – SubjectFull: Activities of daily living
        Type: general
      – SubjectFull: Evaluation research
        Type: general
      – SubjectFull: Accelerometry
        Type: general
      – SubjectFull: Cross-sectional method
        Type: general
      – SubjectFull: Psychology
        Type: general
    Titles:
      – TitleFull: Evaluation of pedometry as a patient-centered outcome in patients undergoing hematopoietic cell transplant (HCT): a comparison of pedometry and patient reports of symptoms, health, and quality of life.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Bennett, Antonia
      – PersonEntity:
          Name:
            NameFull: Reeve, Bryce
      – PersonEntity:
          Name:
            NameFull: Basch, Ethan
      – PersonEntity:
          Name:
            NameFull: Mitchell, Sandra
      – PersonEntity:
          Name:
            NameFull: Meeneghan, Mathew
      – PersonEntity:
          Name:
            NameFull: Battaglini, Claudio
      – PersonEntity:
          Name:
            NameFull: Smith-Ryan, Abbie
      – PersonEntity:
          Name:
            NameFull: Phillips, Brett
      – PersonEntity:
          Name:
            NameFull: Shea, Thomas
      – PersonEntity:
          Name:
            NameFull: Wood, William
      – PersonEntity:
          Name:
            NameFull: Bennett, Antonia V
      – PersonEntity:
          Name:
            NameFull: Reeve, Bryce B
      – PersonEntity:
          Name:
            NameFull: Basch, Ethan M
      – PersonEntity:
          Name:
            NameFull: Mitchell, Sandra A
      – PersonEntity:
          Name:
            NameFull: Battaglini, Claudio L
      – PersonEntity:
          Name:
            NameFull: Smith-Ryan, Abbie E
      – PersonEntity:
          Name:
            NameFull: Shea, Thomas C
      – PersonEntity:
          Name:
            NameFull: Wood, William A
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 03
              Text: Mar2016
              Type: published
              Y: 2016
          Identifiers:
            – Type: issn-print
              Value: 09629343
          Numbering:
            – Type: volume
              Value: 25
            – Type: issue
              Value: 3
          Titles:
            – TitleFull: Quality of Life Research
              Type: main
ResultId 1