View in EDS HTML Full Text PDF Full Text

Active and placebo transcranial magnetic stimulation effects on external and internal auditory hallucinations of schizophrenia.

Saved in:
Bibliographic Details
Title: Active and placebo transcranial magnetic stimulation effects on external and internal auditory hallucinations of schizophrenia.
Authors: Paillère‐Martinot, M.‐L., Galinowski, A., Plaze, M., Andoh, J., Bartrés‐Faz, D., Bellivier, F., Lefaucheur, J.‐P., Rivière, D., Gallarda, T., Martinot, J.‐L., Artiges, E.
Source: Acta Psychiatrica Scandinavica. Mar2017, Vol. 135 Issue 3, p228-238. 11p.
Subjects: Auditory hallucinations, Functional magnetic resonance imaging, Randomized controlled trials, Transcranial magnetic stimulation, Schizophrenia
Abstract: Objective Repetitive transcranial magnetic stimulation ( rTMS) over the left temporo-parietal region has been proposed as a treatment for resistant auditory verbal hallucinations ( AVH), but which patients are more likely to benefit from rTMS is still unclear. This study sought to assess the effects of rTMS on AVH, with a focus on hallucination phenomenology. Method Twenty-seven patients with schizophrenia and medication-resistant AVH participated to a randomized, double-blind, placebo-controlled, add-on rTMS study. The stimulation targeted a language-perception area individually determined using functional magnetic resonance imaging and a language recognition task. AVH were assessed using the hallucination subscale of the Scale for the Assessment of Positive Symptoms ( SAPS). The spatial location of AVH was assessed using the Psychotic Symptom Rating Scales. Results A significant improvement in SAPS hallucination subscale score was observed in both actively treated and placebo-treated groups with no difference between both modalities. Patients with external AVH were significantly more improved than patients with internal AVH, with both modalities. Conclusions A marked placebo effect of rTMS was observed in patients with resistant AVH. Patients with prominent external AVH may be more likely to benefit from both active and placebo interventions. Cortical effects related to non-magnetic stimulation of the auditory cortex are suggested. [ABSTRACT FROM AUTHOR]
Copyright of Acta Psychiatrica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 121198961
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Active and placebo transcranial magnetic stimulation effects on external and internal auditory hallucinations of schizophrenia.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Paillère‐Martinot%2C+M%2E‐L%2E%22">Paillère‐Martinot, M.‐L.</searchLink><br /><searchLink fieldCode="AR" term="%22Galinowski%2C+A%2E%22">Galinowski, A.</searchLink><br /><searchLink fieldCode="AR" term="%22Plaze%2C+M%2E%22">Plaze, M.</searchLink><br /><searchLink fieldCode="AR" term="%22Andoh%2C+J%2E%22">Andoh, J.</searchLink><br /><searchLink fieldCode="AR" term="%22Bartrés‐Faz%2C+D%2E%22">Bartrés‐Faz, D.</searchLink><br /><searchLink fieldCode="AR" term="%22Bellivier%2C+F%2E%22">Bellivier, F.</searchLink><br /><searchLink fieldCode="AR" term="%22Lefaucheur%2C+J%2E‐P%2E%22">Lefaucheur, J.‐P.</searchLink><br /><searchLink fieldCode="AR" term="%22Rivière%2C+D%2E%22">Rivière, D.</searchLink><br /><searchLink fieldCode="AR" term="%22Gallarda%2C+T%2E%22">Gallarda, T.</searchLink><br /><searchLink fieldCode="AR" term="%22Martinot%2C+J%2E‐L%2E%22">Martinot, J.‐L.</searchLink><br /><searchLink fieldCode="AR" term="%22Artiges%2C+E%2E%22">Artiges, E.</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Acta+Psychiatrica+Scandinavica%22">Acta Psychiatrica Scandinavica</searchLink>. Mar2017, Vol. 135 Issue 3, p228-238. 11p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Auditory+hallucinations%22">Auditory hallucinations</searchLink><br /><searchLink fieldCode="DE" term="%22Functional+magnetic+resonance+imaging%22">Functional magnetic resonance imaging</searchLink><br /><searchLink fieldCode="DE" term="%22Randomized+controlled+trials%22">Randomized controlled trials</searchLink><br /><searchLink fieldCode="DE" term="%22Transcranial+magnetic+stimulation%22">Transcranial magnetic stimulation</searchLink><br /><searchLink fieldCode="DE" term="%22Schizophrenia%22">Schizophrenia</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Objective Repetitive transcranial magnetic stimulation ( rTMS) over the left temporo-parietal region has been proposed as a treatment for resistant auditory verbal hallucinations ( AVH), but which patients are more likely to benefit from rTMS is still unclear. This study sought to assess the effects of rTMS on AVH, with a focus on hallucination phenomenology. Method Twenty-seven patients with schizophrenia and medication-resistant AVH participated to a randomized, double-blind, placebo-controlled, add-on rTMS study. The stimulation targeted a language-perception area individually determined using functional magnetic resonance imaging and a language recognition task. AVH were assessed using the hallucination subscale of the Scale for the Assessment of Positive Symptoms ( SAPS). The spatial location of AVH was assessed using the Psychotic Symptom Rating Scales. Results A significant improvement in SAPS hallucination subscale score was observed in both actively treated and placebo-treated groups with no difference between both modalities. Patients with external AVH were significantly more improved than patients with internal AVH, with both modalities. Conclusions A marked placebo effect of rTMS was observed in patients with resistant AVH. Patients with prominent external AVH may be more likely to benefit from both active and placebo interventions. Cortical effects related to non-magnetic stimulation of the auditory cortex are suggested. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Acta Psychiatrica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=121198961
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1111/acps.12680
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 11
        StartPage: 228
    Subjects:
      – SubjectFull: Auditory hallucinations
        Type: general
      – SubjectFull: Functional magnetic resonance imaging
        Type: general
      – SubjectFull: Randomized controlled trials
        Type: general
      – SubjectFull: Transcranial magnetic stimulation
        Type: general
      – SubjectFull: Schizophrenia
        Type: general
    Titles:
      – TitleFull: Active and placebo transcranial magnetic stimulation effects on external and internal auditory hallucinations of schizophrenia.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Paillère‐Martinot, M.‐L.
      – PersonEntity:
          Name:
            NameFull: Galinowski, A.
      – PersonEntity:
          Name:
            NameFull: Plaze, M.
      – PersonEntity:
          Name:
            NameFull: Andoh, J.
      – PersonEntity:
          Name:
            NameFull: Bartrés‐Faz, D.
      – PersonEntity:
          Name:
            NameFull: Bellivier, F.
      – PersonEntity:
          Name:
            NameFull: Lefaucheur, J.‐P.
      – PersonEntity:
          Name:
            NameFull: Rivière, D.
      – PersonEntity:
          Name:
            NameFull: Gallarda, T.
      – PersonEntity:
          Name:
            NameFull: Martinot, J.‐L.
      – PersonEntity:
          Name:
            NameFull: Artiges, E.
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 03
              Text: Mar2017
              Type: published
              Y: 2017
          Identifiers:
            – Type: issn-print
              Value: 0001690X
          Numbering:
            – Type: volume
              Value: 135
            – Type: issue
              Value: 3
          Titles:
            – TitleFull: Acta Psychiatrica Scandinavica
              Type: main
ResultId 1